Search Results - "Hodges, S.L."

Abstract # 2073 Cytokine expression and sickness behavior following lipopolysaccharide stimulation in the Fmr1 knockout mouse by Hodges, S.L., Nolan, S., Tomac, L., Muhammad, I., Lugo, J.

“…Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by a single genetic mutation in the Fragile X mental retardation 1 (FMR1) gene. In addition to…”
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Abstract #4397 Early-life immune insult results in sex-specific quantitative and qualitative differences in ultrasonic vocalizations by Pranske, Z.J., Nolan, S.O., Hodges, S.L., Muhammad, I., Binder, M., Lugo, J.N.

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Abstract # 2076 The acute and long-term impact of prenatal dietary supplementation with omega-3 fatty acids on the behavioral phenotype of the Fmr1 knockout mouse by Nolan, S.O., Hodges, S.L., Okoh, J., Binder, M., Condon, S., Lugo, J.N.

“…Previous work has supported the role of omega-3 fatty acids in the attenuation of the behavioral phenotype of the male Fmr1 knockout mouse model. Given the…”
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The effects of dietary supplementation with n-3 fatty acids on the behavioral and neuroinflammatory phenotype of the Fmr1 knockout mouse by Nolan, S.O., Hodges, S.L., Smith, G.D., Escobar, B., Jefferson, T., Holley, A., Lugo, J.N.

“…Fragile X Syndrome (FXS) is a neurodevelopmental disorder caused by a genetic trinucleotide (CGG) overexpansion mutation in the FMR1 gene coding for fragile X…”
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Characterization of the behavioral phenotype and neuroinflammatory profile of the Fmr1 knockout mouse by Hodges, S.L., Nolan, S., Reynolds, C., Smith, G., Holley, A., Jefferson, T., Huebschman, J., Volquardsen, M., Pandian, A., Taube, J., Lugo, J.

“…Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by a variety of behavioral, intellectual, and physiological abnormalities. It is caused…”
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The α5-GABAAR inverse agonist MRK-016 upregulates hippocampal BDNF expression and prevents cognitive deficits in LPS-treated mice, despite elevations in hippocampal Aβ by Eimerbrink, M.J., Pendry, R.J., Hodges, S.L., Wiles, J.D., Peterman, J.L., White, J.D., Hayes, H.B., Chumley, M.J., Boehm, G.W.

“…•Repeated peripheral LPS administration increases expression of central Aβ.•Administration of MRK-016 post-training rescues memory consolidation following LPS…”
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Administration of the inverse benzodiazepine agonist MRK-016 rescues acquisition and memory consolidation following peripheral administration of bacterial endotoxin by Eimerbrink, M.J., White, J.D., Pendry, R.J., Hodges, S.L., Sadler, L.N., Wiles, J.D., Weintraub, M.K., Chumley, M.J., Boehm, G.W.

“…•MRK-016 rescued memory acquisition following peripheral LPS administration.•MRK-016 rescued memory consolidation following peripheral LPS…”
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Pre-treatment of C57BL6/J mice with the TLR4 agonist monophosphoryl lipid A prevents LPS-induced sickness behaviors and elevations in dorsal hippocampus interleukin-1β, independent of interleukin-4 expression by Eimerbrink, M.J., Kranjac, D., St. Laurent, C., White, J.D., Weintraub, M.K., Pendry, R.J., Madigan, R., Hodges, S.L., Sadler, L.N., Chumley, M.J., Boehm, G.W.

“…•MPLA administration can trigger expression of sickness behaviors in C57BL/6J mice.•Treatment with MPLA for two consecutive days prior to LPS administration is…”
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Infertility in transgenic female mice with human growth hormone expression: evidence for luteal failure by Bartke, A, Steger, R W, Hodges, S L, Parkening, T A, Collins, T J, Yun, J S, Wagner, T E

“…Introduction of the human growth hormone (hGH) gene fused with mouse metallothionein I promoter into domestic mice leads to ectopic synthesis of hGH, marked…”
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