Search Results - "Hodemaekers, Hennie M"
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1
Evaluation of Adverse Effects of Resorbable Hyaluronic Acid Fillers: Determination of Macrophage Responses
Published in International journal of molecular sciences (30-06-2022)“…Resorbable tissue fillers for aesthetic purposes can induce severe complications including product migration, late swelling, and inflammatory reactions. The…”
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2
Genetic Susceptibility to Respiratory Syncytial Virus Bronchiolitis Is Predominantly Associated with Innate Immune Genes
Published in The Journal of infectious diseases (15-09-2007)“…Background. Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infection in infants. Only a proportion of children infected…”
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3
Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis
Published in PloS one (19-02-2016)“…Pertussis, caused by infection with the gram negative B. pertussis bacterium, is a serious respiratory illness that can last for months. While B. pertussis…”
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4
Analysis of Lipid Metabolism, Immune Function, and Neurobehavior in Adult C57BL/6JxFVB Mice After Developmental Exposure to di (2-ethylhexyl) Phthalate
Published in Frontiers in endocrinology (Lausanne) (21-11-2018)“…Developmental exposure to di (2-ethylhexyl) phthalate (DEHP) has been implicated in the onset of metabolic syndrome later in life. Alterations in neurobehavior…”
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5
Genetic predisposition of RSV infection-related respiratory morbidity in preterm infants
Published in European journal of pediatrics (01-07-2014)“…The aim of this study was to assess whether prematurely born infants have a genetic predisposition to respiratory syncytial virus (RSV) infection-related…”
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Programmed Effects in Neurobehavior and Antioxidative Physiology in Zebrafish Embryonically Exposed to Cadmium: Observations and Hypothesized Adverse Outcome Pathway Framework
Published in International journal of molecular sciences (01-11-2016)“…Non-communicable diseases (NCDs) are a major cause of premature mortality. Recent studies show that predispositions for NCDs may arise from early-life exposure…”
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7
Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze
Published in Respiratory research (12-09-2011)“…Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in infants. Following RSV bronchiolitis, 50% of children develop post-bronchiolitis…”
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8
Development and comparison of two assay formats for parallel detection of four biothreat pathogens by using suspension microarrays
Published in PloS one (15-02-2012)“…Microarrays provide a powerful analytical tool for the simultaneous detection of multiple pathogens. We developed diagnostic suspension microarrays for…”
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9
Association of Severe Respiratory Syncytial Virus Bronchiolitis with Interleukin-4 and Interleukin-4 Receptor α Polymorphisms
Published in The Journal of infectious diseases (01-01-2003)“…The association of variants of genes encoding interleukin (IL)–4 and the IL-4 receptor α chain (IL-4Rα) with respiratory syncytial virus (RSV) bronchiolitis…”
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10
Systemic signature of the lung response to respiratory syncytial virus infection
Published in PloS one (24-06-2011)“…Respiratory Syncytial Virus is a frequent cause of severe bronchiolitis in children. To improve our understanding of systemic host responses to RSV, we…”
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11
Gene Expression Differences in Lungs of Mice during Secondary Immune Responses to Respiratory Syncytial Virus Infection
Published in Journal of Virology (15-09-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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12
Influence of Promoter Variants of Interleukin-10, Interleukin-9, and Tumor Necrosis Factor–α Genes on Respiratory Syncytial Virus Bronchiolitis
Published in The Journal of infectious diseases (15-01-2004)“…Previously, we reported genetic associations between severe respiratory syncytial virus (RSV) bronchiolitis in infants and polymorphisms in the interleukin…”
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13
Dose Addition in the Induction of Craniofacial Malformations in Zebrafish Embryos Exposed to a Complex Mixture of Food-Relevant Chemicals with Dissimilar Modes of Action
Published in Environmental health perspectives (01-04-2022)“…Humans are exposed to combinations of chemicals. In cumulative risk assessment (CRA), regulatory bodies such as the European Food Safety Authority consider…”
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Neuronal differentiation pathways and compound-induced developmental neurotoxicity in the human neural progenitor cell test (hNPT) revealed by RNA-seq
Published in Chemosphere (Oxford) (01-10-2022)“…There is an increased awareness that the use of animals for compound-induced developmental neurotoxicity (DNT) testing has limitations. Animal-free…”
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The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish
Published in Toxicology and applied pharmacology (15-11-2020)“…The zebrafish embryo toxicity test (ZFET) is a simple medium-throughput test to inform about (sub)acute lethal effects in embryos. Enhanced analysis through…”
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Transcriptomics in lung tissue upon respiratory syncytial virus infection reveals aging as important modulator of immune activation and matrix maintenance
Published in Scientific reports (09-11-2018)“…Aging poses an increased risk of severe infection by respiratory syncytial virus (RSV). The many different biological pathways comprising the response to…”
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17
Zebrafish embryos as a screen for DNA methylation modifications after compound exposure
Published in Toxicology and applied pharmacology (15-01-2016)“…Modified epigenetic programming early in life is proposed to underlie the development of an adverse adult phenotype, known as the Developmental Origins of…”
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Distinguishing mode of action of compounds inducing craniofacial malformations in zebrafish embryos to support dose-response modeling in combined exposures
Published in Reproductive toxicology (Elmsford, N.Y.) (01-09-2020)“…[Display omitted] •Discernable gene expression profiles for MOAs of reference compounds.•GE profiles of unknown compounds can be matched with reference…”
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19
A high crosslinking grade of hyaluronic acid found in a dermal filler causing adverse effects
Published in Journal of pharmaceutical and biomedical analysis (10-09-2018)“…[Display omitted] •A method is developed for the routine analysis of dermal filler products.•The method is used to identify modified hyaluronic acid and to…”
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Differential effects of fluoxetine and venlafaxine in the neural embryonic stem cell test (ESTn) revealed by a cell lineage map
Published in Neurotoxicology (Park Forest South) (01-01-2020)“…•The in vitro neural embryonic stem cell test (ESTn) mimics neural differentiation.•A cell lineage map of neural differentiation tracks gene expression of cell…”
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