Search Results - "Hodawadekar, S C"
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Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design
Published in Oncogene (13-08-2007)“…The post-translational modification of histones plays an important role in chromatin regulation, a process that insures the fidelity of gene expression and…”
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Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers
Published in Current biology (01-08-2000)“…Background: The nucleotide-binding protein Fhit, among the earliest and most frequently inactivated proteins in lung cancer, suppresses tumor formation by…”
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Adenosine Monophosphoramidase Activity of Hint and Hnt1 Supports Function of Kin28, Ccl1, and Tfb3
Published in The Journal of biological chemistry (29-03-2002)“…The histidine triad superfamily of nucleotide hydrolases and nucleotide transferases consists of a branch of proteins related to Hint and Aprataxin, a branch…”
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Fhit-nucleotide Specificity Probed with Novel Fluorescent and Fluorogenic Substrates
Published in The Journal of biological chemistry (18-02-2000)“…Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins, binds and cleaves diadenosine polyphosphates and functions as a tumor…”
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