Search Results - "Hockman, Steven C"

Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury by Chung, Youn Wook, Lagranh, Claudia, Chen, Yong, Sun, Junhui, Tong, Guang, Hockman, Steven C., Ahmad, Faiyaz, Esfahani, Shervin G., Bae, Dahae H., Polidovitch, Nazari, Wu, Jian, Rhee, Dong Keun, Lee, Beom Seob, Gucek, Marjan, Daniels, Mathew P., Brantner, Christine A., Backx, Peter H., Murphy, Elizabeth, Manganiello, Vincent C.

“…Although inhibition of cyclic nucleotide phosphodiesterase type 3 (PDE3) has been reported to protect rodent heart against ischemia/reperfusion (I/R) injury,…”
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SFPQ, a multifunctional nuclear protein, regulates the transcription of PDE3A by Rhee, Dong Keun, Hockman, Steven C, Choi, Sun-Kyung, Kim, Yong-Eun, Park, Chungoo, Manganiello, Vincent C, Kim, Kee Kwang

“…Phosphodiesterase 3A (PDE3A), a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (PDE) family, plays important roles in oocyte maturation and…”
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Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST) by Vandenberghe, Pierre, Hagué, Perrine, Hockman, Steven C, Manganiello, Vincent C, Demetter, Pieter, Erneux, Christophe, Vanderwinden, Jean-Marie

“…We previously identified phosphodiesterase 3A (PDE3A) as a marker for interstitial cells of Cajal (ICC) in adult mouse gut. However, PDE3A expression and…”
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Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue by Ahmad, Faiyaz, Chung, Youn Wook, Tang, Yan, Hockman, Steven C., Liu, Shiwei, Khan, Yusuf, Huo, Kevin, Billings, Eric, Amar, Marcelo J., Remaley, Alan T., Manganiello, Vincent C.

“…Activation of inflammation in white adipose tissue (WAT), includes infiltration/expansion of WAT macrophages, contributes pathogenesis of obesity, insulin…”
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White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function by Chung, Youn Wook, Ahmad, Faiyaz, Tang, Yan, Hockman, Steven C., Kee, Hyun Jung, Berger, Karin, Guirguis, Emilia, Choi, Young Hun, Schimel, Dan M., Aponte, Angel M., Park, Sunhee, Degerman, Eva, Manganiello, Vincent C.

“…Understanding mechanisms by which a population of beige adipocytes is increased in white adipose tissue (WAT) reflects a potential strategy in the fight…”
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Effects of heterologous expression of human cyclic nucleotide phosphodiesterase 3A (hPDE3A) on redox regulation in yeast by Rhee, Dong Keun, Lim, Jung Chae, Hockman, Steven C, Ahmad, Faiyaz, Woo, Dong Ho, Chung, Youn Wook, Liu, Shiwei, Hockman, Allison L, Manganiello, Vincent C

“…Oxidative stress plays a pivotal role in pathogenesis of cardiovascular diseases and diabetes; however, the roles of protein kinase A (PKA) and human…”
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Phosphodiesterase 3B (PDE3B) Regulates NLRP3 Inflammasome and Metabolic Cross Talk in Adipose Tissue by Khan, Faiyaz Ahmad, Chung, Youn Wook, Tang, Yan, Hockman, Steven C, Liu, Steve, Khan, Yusuf, Huo, Kevin, Amar, Marcelo J, Remaley, Alan T, Manganiello, Vincent C

“…Abstract only Activation of inflammation in white adipose tissue (WAT) which includes infiltration/expansion of WAT macrophages contributes to pathogenesis of…”
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Heterologous expression of human phosphodiesterase 3A enhances oxidative stress resistance in yeast by Rhee, Dong Keun, Lim, Jung Chae, Hockman, Steven C., Ahmad, Faiyaz, Manganiello, Vincent C.

“…Abstract only All organisms have evolved to overcome environmental stress via protective antioxidant activity, which slows ageing or senescence and extends…”
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Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase by Taira, M., Hockman, S.C., Calvo, J.C., Belfrage, P., Manganiello, V.C.

“…Two distinct but related cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI PDE) cDNAs were cloned from rat adipose tissue cDNA libraries. The open…”
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