Search Results - "Hockenbery, D"

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry by Morrish, F, Isern, N, Sadilek, M, Jeffrey, M, Hockenbery, D M

“…Cell proliferation requires the coordinated activity of cytosolic and mitochondrial metabolic pathways to provide ATP and building blocks for DNA, RNA and…”
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Defining apoptosis by HOCKENBERY, D

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Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration by Sweet, I. R., Gilbert, M., Maloney, E., Hockenbery, D. M., Schwartz, M. W., Kim, F.

“…Aims/hypothesis Exposure of endothelial cells to high glucose levels suppresses responses to insulin, including induction of endothelial nitric oxide synthase…”
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Bcl-2 functions in an antioxidant pathway to prevent apoptosis by Hockenbery, D M, Oltvai, Z N, Yin, X M, Milliman, C L, Korsmeyer, S J

“…Bcl-2 inhibits most types of apoptotic cell death, implying a common mechanism of lethality. Bcl-2 is localized to intracellular sites of oxygen free radical…”
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BCL2 Protein is Topographically Restricted in Tissues Characterized by Apoptotic Cell Death by Hockenbery, David M., Zutter, Mary, Hickey, William, Nahm, Moon, Korsmeyer, Stanley J.

“…The BCL2 protooncogene encodes an inner mitochondrial membrane protein that blocks programmed cell death. BCL2 was isolated from the chromosomal breakpoint of…”
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Bcl-2-related survival proteins by Schwartz, P S, Hockenbery, D M

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The Adenovirus E1A Proteins Induce Apoptosis, which is Inhibited by the E1B 19-kDa and Bcl-2 Proteins by Rao, Lakshmi, Debbas, Michael, Sabbatini, Peter, Hockenbery, David, Korsmeyer, Stanley, White, Eileen

“…Cooperation between the adenovirus E1A and E1B oncogenes is required for transformation of primary quiescent rodent cells. Although expression of E1A alone…”
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Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3 by Hockenbery, David M, Tzung, Shie-Pon, Kim, Kristine M, Basañez, Gorka, Giedt, Chris D, Simon, Julian, Zimmerberg, Joshua, Zhang, Kam Y. J

“…The Bcl-2-related survival proteins confer cellular resistance to a wide range of agents. Bcl-xL-expressing hepatocyte cell lines are resistant to tumour…”
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bcl-2 in cancer, development and apoptosis by Hockenbery, David M.

“…The bcl-2 gene provides a window on the basic cellular machinery of apoptosis or programmed cell death, a process involved in virtually all biologic events in…”
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Expression of Bcl-2 family during liver regeneration and identification of Bcl-x as a delayed early response gene by Tzung, SP, Fausto, N, Hockenbery, DM

“…Induction of Bcl-2 and Bcl-x has been demonstrated in mitogen-stimulated lymphocytes in vitro, suggesting that these two apoptosis modulators may also play a…”
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Biophysical Characterization of Recombinant Human Bcl-2 and Its Interactions with an Inhibitory Ligand, Antimycin A by Kim, Kristine M, Giedt, Chris D, Basañez, Gorka, O'Neill, Jason W, Hill, John J, Han, Yi-Hong, Tzung, Shie-Pon, Zimmerberg, Joshua, Hockenbery, David M, Zhang, Kam Y. J

“…Apoptosis is an essential physiological process, regulated by the family of Bcl-2-related proteins. However, the molecular mechanism by which Bcl-2 regulates…”
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Efficacy of neodymium:YAG laser therapy for gastric antral vascular ectasia (GAVE) following hematopoietic cell transplant by SELINGER, R. R. E, MCDONALD, G. B, HOCKENBERY, D. M, STEINBACH, G, KIMMEY, M. B

“…We determined the incidence of severe bleeding from gastric antral vascular ectasia (GAVE) after myeloablative hematopoietic cell transplant and the outcomes…”
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Oral beclomethasone dipropionate for treatment of intestinal graft-versus-host disease: A randomized, controlled trial by McDonald, George B., Bouvier, Michelle, Hockenbery, David M., Stern, Jean M., Gooley, Ted, Farrand, Allen, Murakami, Carol, Levine, Douglas S.

“…Background & Aims: Beclomethasone dipropionate (BDP), a topically active steroid, seemed to be an effective treatment for intestinal graft-versus-host disease…”
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Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines by Nunez, G, London, L, Hockenbery, D, Alexander, M, McKearn, JP, Korsmeyer, SJ

“…The t(14;18) of human follicular B cell lymphoma translocates the Bcl-2 gene into the Ig H chain locus and markedly deregulates Bcl-2 expression. We sought to…”
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Primitive Human Hematopoietic Precursors Express Bcl-x But Not Bcl-2 by Park, Julie R., Bernstein, Irwin D., Hockenbery, David M.

“…Bcl-2 and its homologue, bcl-xL, encode membrane-associated proteins that suppress programmed cell death of hematopoietic cell lines after growth factor…”
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Mitochondrial Proliferation and Paradoxical Membrane Depolarization during Terminal Differentiation and Apoptosis in a Human Colon Carcinoma Cell Line by Mancini, Mariangela, Anderson, Benjamin O., Caldwell, Elizabeth, Sedghinasab, Monireh, Paty, Philip B., Hockenbery, David M.

“…Herbimycin A, a tyrosine kinase inhibitor, induces cellular differentiation and delayed apoptosis in Colo-205 cells, a poorly differentiated human colon…”
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MYC and mitochondrial biogenesis by Morrish, Fionnuala, Hockenbery, David

“…Mitochondria, the powerhouses of the cell, face two imperatives concerning biogenesis. The first is the requirement for dividing cells to replicate their…”
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Persistent nausea and anorexia after marrow transplantation : A prospective study of 78 patients by WU, D, HOCKENBERY, D. M, BRENTNALL, T. A, BAEHR, P. H, PONEC, R. J, KUVER, R, TZUNG, S.-P, TODARO, J. L, MCDONALD, G. B

“…Persistent nausea, vomiting, anorexia, and poor oral intake are common after hematopoietic cell transplantation. In the past, herpesvirus infections and acute…”
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bcl-2, a novel regulator of cell death by Hockenbery, D M

“…The bcl-2 gene product, a 25 kDa membrane protein residing at mitochondrial, microsomal and nuclear membrane sites within many cell types, is a broad and…”
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Successful medical treatment of intestinal ulceration caused by Rhizopus microsporus by Pinto-Marques, P, Hockenbery, D M, Hackman, R C, Tapper, D, McDonald, G B

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