Search Results - "Hochwald, S N"

Altered LKB1 CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion by Gu, Y, Lin, S, Li, J-L, Nakagawa, H, Chen, Z, Jin, B, Tian, L, Ucar, D A, Shen, H, Lu, J, Hochwald, S N, Kaye, F J, Wu, L

“…LKB1 is a tumor susceptibility gene for the Peutz–Jeghers cancer syndrome and is a target for mutational inactivation in sporadic human malignancies. LKB1…”
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Review of Minimally Invasive Esophagectomy and Current Controversies by Kim, T., Hochwald, Steven N., Sarosi, G. A., Caban, A. M., Rossidis, G., Ben-David, K.

“…Esophagectomy is a complex operation with significant morbidity and mortality. Minimally invasive esophagectomy (MIE) was described in the 1990s in an effort…”
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Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis by Zhang, J, Gao, Q, Zhou, Y, Dier, U, Hempel, N, Hochwald, S N

“…Cancer cells often gains a growth advantage by taking up glucose at a high rate and undergoing aerobic glycolysis through intrinsic cellular factors that…”
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Primary duodenal adenocarcinoma : A ten-year experience with 79 patients by ROSE, D. M, HOCHWALD, S. N, KLIMSTRA, D. S, BRENNAN, M. F

“…Duodenal adenocarcinoma is a rare malignancy with a poorly defined natural history and outcome. The factors that affect management and survival of patients…”
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Early postoperative enteral feeding improves whole body protein kinetics in upper gastrointestinal cancer patients by Hochwald, Steven N., Harrison, Lawrence E., Heslin, Martin J., Burt, Michael E., Brennan, Murray F.

“…Patients with upper gastrointestinal (Gl) tract malignancies are at increased risk for malnutrition, as well as postoperative morbidity and mortality. As data…”
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Blumgart anastomosis for pancreaticojejunostomy minimizes severe complications after pancreatic head resection (Br J Surg 2009; 96: 741-750) by Grobmyer, S. R., Kooby, D. A., Hochwald, S. N., Blumgart, L. H.

“…The Editors welcome topical correspondence from readers relating to articles published in the Journal. Responses should be sent electronically via the BJS…”
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Nuclear factor-κB is upregulated in colorectal cancer by Lind, D.Scott, Hochwald, Steven N., Malaty, John, Rekkas, Stelio, Hebig, Paul, Mishra, Girish, Moldawer, Lyle L., Copeland, Edward M., MacKay, Sally

“…Background. Chemoresistance may involve the anti-apoptotic transcriptional regulator, nuclear factor-κB (NF-κB). The purpose of this study was to determine…”
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Gastric remnant carcinoma: Just another proximal gastric cancer or a unique entity? by Newman, Elliot, Brennan, Murray F., Hochwald, Steven N., Harrison, Lawrence E., Karpeh, Martin S.

“…Gastric cancer that occurs 5 or more years after distal gastric resection for benign disease is defined as gastric remnant carcinoma (GRC). The purpose of this…”
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Hilar Cholangiocarcinoma: patterns of spread, the importance of hepatic resection for curative operation, and a presurgical clinical staging system by Burke, E C, Jarnagin, W R, Hochwald, S N, Pisters, P W, Fong, Y, Blumgart, L H

“…To determine the resectability rate for hilar cholangiocarcinoma, to analyze reasons for unresectability, and to devise a presurgical clinical T-staging…”
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Giant Hepatic Hemangioma with Kasabach-Merritt Syndrome: Is the Appropriate Treatment Enucleation or Liver Transplantation? by Hochwald, S N, Blumgart, L H

“…We present a case of giant cavernous hemangioma of the liver with disseminated intravascular coagulopathy (Kasabach-Merritt syndrome) which was cured by…”
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Association of preoperative biliary stenting with increased postoperative infectious complications in proximal cholangiocarcinoma by Hochwald, S N, Burke, E C, Jarnagin, W R, Fong, Y, Blumgart, L H

“…The indications for preoperative biliary stenting in patients with obstructive jaundice are controversial. We evaluated the effect of preoperative biliary…”
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Early Postoperative Enteral Nutrition Improves Peripheral Protein Kinetics in Upper Gastrointestinal Cancer Patients Undergoing Complete Resection: A Randomized Trial by Harrison, Lawrence E., Hochwald, Steven N., Heslin, Martin J., Berman, Russell, Burt, Michael, Brennan, Murray F.

“…Background: Patients with upper gastrointestinal (GI) tract malignancies are at risk for malnutrition and postoperative morbidity and mortality. We examined…”
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A prospective, randomized trial of early enteral feeding after resection of upper gastrointestinal malignancy by Heslin, M J, Latkany, L, Leung, D, Brooks, A D, Hochwald, S N, Pisters, P W, Shike, M, Brennan, M F

“…The purpose of the study was to determine whether early postoperative enteral feeding with an immune-enhancing formula (IEF) decreases morbidity, mortality,…”
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Use of an automated circuit for isolated limb infusion for malignancy by Grobmyer, S.R, Filichia, L, Robinson, A.R, Clark, T.D, Vaughn, K, Copeland, E.M, Hochwald, S.N

“…Abstract Background Isolated limb infusion (ILI) for recurrent or in-transit melanoma is an accepted technique that allows high-dose chemotherapy to be…”
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Intestinal Permeability After Early Postoperative Enteral Nutrition in Patients With Upper Gastrointestinal Malignancy by Brooks, Ari D., Hochwald, Steven N., Heslin, Martin J., Harrison, Lawrence E., Burt, Michael, Brennan, Murray F.

“…Background: Increased intestinal permeability may lead to sepsis in resected upper gastrointestinal (GI) cancer patients. This study sought to determine…”
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Isolated lung perfusion with doxorubicin reduces cardiac and host toxicities associated with systemic administration by Bruce, Ng, Hochwald, Steven N., Burt, Michael E.

“…For patients with malignant neoplasms metastalic to lung, systemic chemotherapy in doses high enough to achieve significant survival improvement is often…”
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A preoperative biliary stent is associated with increased complications after pancreatoduodenectomy by Heslin, M J, Brooks, A D, Hochwald, S N, Harrison, L E, Blumgart, L H, Brennan, M F

“…A preoperative biliary stent is commonly used after the initial evaluation of the patient with a periampullary mass. To evaluate the effect of a preoperative…”
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Revised technique of isolated lung perfusion in the rat by Wang, Hong-Yue, Port, Jeffrey L., Hochwald, Steven N., Burt, Michael E.

“…Isolated lung perfusion in the rat is useful research tool. Pulmonary arteriotomy and venotomy repair is required for animal survival. Rat pulmonary vessels…”
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Depletion of high energy phosphate compounds in the tumor-bearing state and reversal after tumor resection by Hochwald, Steven N., Harrison, Lawrence E., Port, Jeffrey L., Blumberg, David, Brennan, Murray F., Burt, Michael

“…Background. Cancer cachexia is a syndrome manifested by a variety of metabolic abnormalities that include depletion of host energy stores. We studied liver and…”
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γ-Glutamyl Transpeptidase Mediation of Tumor Glutathione Utilization In Vivo by Hochwald, Steven N., Harrison, Lawrence E., Rose, D. Michael, Anderson, Mary, Burt, Michael E.

“…Background Glutathione is a tripeptide used by cells to protect against oxidative and free radical damage. It may also be involved in biochemical mechanisms…”
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