Search Results - "Hobson, Joshua"
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Cardiometabolic risk factors are associated with immune cell mitochondrial respiration in humans
Published in American journal of physiology. Heart and circulatory physiology (01-08-2020)“…Modifiable cardiometabolic risk factors induce the release of proinflammatory cytokines and reactive oxygen species from circulating peripheral blood…”
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Blood lipid markers are associated with hippocampal viscoelastic properties and memory in humans
Published in Journal of cerebral blood flow and metabolism (01-06-2021)“…Age-related memory loss shares similar risk factors as cardiometabolic diseases including elevated serum triglycerides (TGs) and low-density lipoprotein…”
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Altered endothelial ET B receptor expression in postmenopausal women
Published in American journal of physiology. Heart and circulatory physiology (01-07-2020)“…The endothelin system plays an important role in mediating vascular function. The endothelin-B receptor (ET R) on endothelial cells mediates vasodilation via…”
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ET B receptor-mediated vasodilation is regulated by estradiol in young women
Published in American journal of physiology. Heart and circulatory physiology (01-09-2021)“…The endothelin-B (ET ) receptor is a key regulator of vascular endothelial function in women. We have previously shown that the ET receptor mediates…”
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Delivery of neostigmine and glycopyrrolate by iontophoresis: a nonrandomized study in individuals with spinal cord injury
Published in Spinal cord (01-03-2018)“…Study design Phase I Clinical Trial. Objectives In this proof-of-principle study, the effectiveness and safety of transdermal administration of…”
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Establishing a threshold to predict risk of cardiovascular disease from the serum triglyceride and high-density lipoprotein concentrations in persons with spinal cord injury
Published in Spinal cord (01-11-2018)“…Study design Retrospective cohort. Objective This report identified the serum triglyceride (TG) concentrations in persons with spinal cord injury (SCI) and…”
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Predicting Cardiometabolic Risk From Visceral Abdominal Adiposity in Persons With Chronic Spinal Cord Injury
Published in Journal of clinical densitometry (01-07-2021)“…Persons with spinal cord injury (SCI) have increased adiposity that may predispose to cardiovascular disease compared to those who are able-bodied (AB). The…”
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Progressive Sublesional Bone Loss Extends into the Second Decade After Spinal Cord Injury
Published in Journal of clinical densitometry (01-04-2019)“…Objective: The rate of areal bone mineral density (aBMD) loss at the knee (distal femur (DF) and proximal tibia ) and hip (femoral neck (FN) and total hip…”
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Fenofibrate therapy to lower serum triglyceride concentrations in persons with spinal cord injury: A preliminary analysis of its safety profile
Published in The journal of spinal cord medicine (02-09-2020)“…Context: Fenofibrate is used to treat elevated serum triglyceride (TG) concentrations (e.g. ≥150 mg/dl). The lipoprotein profile of most individuals with…”
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A Four Month Randomized Controlled Trial on the Efficacy of Once-daily Fenofibrate Monotherapy in Persons with Spinal Cord Injury
Published in Scientific reports (20-11-2019)“…An open-label, randomized clinical trial of once-daily fenofibrate monotherapy administered for 2- (Mo2) and 4- (Mo4) months using modified intervention…”
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Administration of Denosumab Preserves Bone Mineral Density at the Knee in Persons With Subacute Spinal Cord Injury: Findings From a Randomized Clinical Trial
Published in JBMR plus (01-08-2020)“…ABSTRACT Persons with neurologically motor‐complete spinal cord injury (SCI) have a marked loss of bone mineral density (BMD) of the long bones of the lower…”
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Bronchodilator effects of ipratropium bromide and albuterol sulfate among subjects with tetraplegia
Published in The journal of spinal cord medicine (02-01-2018)“…Objective: In addition to lung volume restriction, persons with chronic tetraplegia demonstrate obstructive airway physiology evinced by…”
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13
Cutaneous microvascular perfusion responses to insulin iontophoresis are differentially affected by insulin resistance after spinal cord injury
Published in Experimental physiology (01-09-2017)“…New Findings What is the central question of this study? What impact does insulin resistance have on cutaneous perfusion responses to insulin iontophoresis in…”
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The Impact of ET B Receptors on the Axon Reflex During Local Heating in Healthy Young Women
Published in The FASEB journal (01-05-2021)“…Abstract only…”
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The Impact of ETB Receptors on the Axon Reflex During Local Heating in Healthy Young Women
Published in The FASEB journal (01-05-2021)“…Endothelin‐1 (ET‐1) is a vasoconstrictor that acts on the vasculature through ETA and ETB receptors. Both ETA and ETB receptors are located in the skin and are…”
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Relation between cerebrovascular function and hippocampal viscoelastic properties in humans
Published in The FASEB journal (01-05-2021)“…Age‐related memory loss shares many of the same modifiable risk factors as cardiometabolic diseases including cerebrovascular dysfunction and dyslipidemia…”
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The Relation between Immune Cell Mitochondrial Respiration and Brachial Artery Pulse Pressure in Humans
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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Sex differences in ET‐1 levels in primary human endothelial cells
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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ET‐1 Receptor Function in Women of Different Reproductive Age but Similar Chronological Age
Published in The FASEB journal (01-05-2021)“…Endothelial dysfunction is a primary driver of hypertension and cardiovascular disease. Our lab has previously shown that endothelin‐1 (ET‐1), which…”
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Impact of Habitual Aerobic Exercise on Arterial Stiffness in Perimenopausal Women
Published in The FASEB journal (01-05-2021)“…Arterial stiffness progressively increases with age, and is associated with increased risk of cardiovascular disease. Although postmenopausal women have higher…”
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