Search Results - "Hobson, James"

Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies by Hobson, James J., Al-khouja, Amer, Curley, Paul, Meyers, David, Flexner, Charles, Siccardi, Marco, Owen, Andrew, Meyers, Caren Freel, Rannard, Steve P.

“…The increasing global prevalence of human immunodeficiency virus (HIV) is estimated at 36.7 million people currently infected. Lifelong antiretroviral (ARV)…”
Get full text

Branched copolymer-stabilised nanoemulsions as new candidate oral drug delivery systems by Hobson, James J, Edwards, Stephanie, Slater, Rebecca A, Martin, Philip, Owen, Andrew, Rannard, Steve P

“…The delivery of drugs to the bloodstream oral administration may suffer from a number of complications including poor dissolution, first pass metabolism and…”
Get full text

Systemic delivery of bictegravir and tenofovir alafenamide using dissolving microneedles for HIV preexposure prophylaxis by Zhang, Chunyang, Wu, Yu, Hutton, Aaron R.J., Hidayat Bin Sabri, Akmal, Hobson, James J., Savage, Alison C., McCarthy, Helen O, Paredes, Alejandro J., Owen, Andrew, Rannard, Steven P., Donnelly, Ryan F.

“…[Display omitted] Human immunodeficiency virus (HIV) continues to pose a serious threat to global health. Oral preexposure prophylaxis (PrEP), considered…”
Get full text

Evaluating the feasibility and acceptability of a co-designed physical activity intervention for rural middle schoolers: a pilot study by Watkins, Janette M, Brunnemer, Julia E, Heeter, Kathleen N, Medellin, Andrew M, Churchill, William C, Goss, Janelle M, Hobson, James M, Werner, Nicole E, Weaver, R Glenn, Kercher, Vanessa M Martinez, Kercher, Kyle A

“…Lack of physical activity is a concern for children across diverse backgrounds, particularly affecting those in rural areas who face distinct challenges…”
Get full text

Mucus-responsive functionalized emulsions: design, synthesis and study of novel branched polymers as functional emulsifiers by Edwards, Stephanie E, Flynn, Sean, Hobson, James J, Chambon, Pierre, Cauldbeck, Helen, Rannard, Steve P

“…Mucus lines the moist cavities throughout the body, acting as barrier by protecting the underlying cells against the external environment, but it also hinders…”
Get full text

Human-centered participatory co-design with children and adults for a prototype lifestyle intervention and implementation strategy in a rural middle school by Watkins, Janette M, Greeven, Sarah J, Heeter, Kathleen N, Brunnemer, Julia E, Otile, Jacob, Solá, Paola A Fernández, Dutta, Sandeep, Hobson, James M, Evanovich, Justin M, Coble, Cassandra J, Werner, Nicole E, Martinez Kercher, Vanessa M, Kercher, Kyle A

“…The significance of regular physical activity (PA) in reducing cardiovascular disease (CVD) risk is widely acknowledged. However, children in rural areas…”
Get full text

Safety assessment of a new nanoemulsion-based drug-delivery system reveals unexpected drug-free anticoagulant activity by Hobson, James J, Rannard, Steve P, Owen, Andrew, Liptrott, Neill J

“…A preclinical safety assessment of a novel nanoemulsion drug-delivery system, initially developed to improve the posology of efavirenz (EFV), was conducted…”
Get full text

The potential value of nanomedicine and novel oral dosage forms in the treatment of HIV by Hobson, James J, Owen, Andrew, Rannard, Steve P

“…The most recent estimates place the number of infected patients worldwide in excess of 36million (upper limit>40million) (1), but the success of antiretroviral…”
Get full text

An investigation of first year university students' confidence in using academic literacies by Nallaya, Shashi, Hobson, James E, Ulpen, Tamra

“…Commencing students in universities today are very diverse with regards to their academic preparation, language, and cultural background. Some of these…”
Get full text

Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection by Hobson, James J, Savage, Alison C, Dwyer, Andrew B, Unsworth, Catherine, Massam, Jonathan, Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith K R, Neary, Megan, Sharp, Joanne, Valentijn, Anthony, David, Christopher, Curley, Paul, Liptrott, Neill J, McDonald, Tom O, Owen, Andrew, Rannard, Steve P

“…The control of COVID-19 across the world requires the formation of a range of interventions including vaccines to elicit an immune response and…”
Get more information

Refined Feasibility Testing of an 8-Week Sport and Physical Activity Intervention in a Rural Middle School by Watkins, Janette M, Goss, Janelle M, Major, McKenna G, Kwaiser, Megan M, Medellin, Andrew M, Hobson, James M, Martinez Kercher, Vanessa M, Kercher, Kyle A

“…This study examines how the 8-week Hoosier Sport program impacts cardiovascular disease (CVD) risks by promoting physical activity (PA) among rural, low-income…”
Get full text

Online Course Quality Evaluation Instruments: A Scoping Review by McInnes, Richard, Hobson, James E, Johnson, Kerry Lorette, Cramp, Joshua, Aitchison, Claire, Baldock, Katherine L

“…How do we make judgements about the quality of online courses? Checklists and rubrics are commonplace in Higher Education for establishing and measuring design…”
Get full text

Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations by Curley, Paul, Hobson, James J, Liptrott, Neill J, Makarov, Edward, Al-Khouja, Amer, Tatham, Lee, David, Christopher A W, Box, Helen, Neary, Megan, Sharp, Joanne, Pertinez, Henry, Meyers, David, Flexner, Charles, Freel Meyers, Caren L, Poluektova, Larisa, Rannard, Steve, Owen, Andrew

“…Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of…”
Get full text

Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters by Neary, Megan, Sharp, Joanne, Gallardo-Toledo, Eduardo, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Cox, Helen, Tatham, Lee, Box, Helen, Curley, Paul, Arshad, Usman, Rajoli, Rajith K. R., Pertinez, Henry, Valentijn, Anthony, Dhaliwal, Kevin, Mc Caughan, Frank, Hobson, James, Rannard, Steve, Kipar, Anja, Stewart, James P., Owen, Andrew

“…The successful development of a chemoprophylaxis against SARS-CoV-2 could provide a tool for infection prevention that is implementable alongside vaccination…”
Get full text

Multilevel needs assessment of physical activity, sport, psychological needs, and nutrition in rural children and adults by Greeven, Sarah J, Medellin, Andrew M, Watkins, Janette M, Coble, Cassandra J, Brunnemer, Julia E, Fernández Solá, Paola A, Dutta, Sandeep, Hobson, James M, Evanovich, Justin M, Martinez Kercher, Vanessa M, Kercher, Kyle A

“…Physical activity yields significant benefits, yet fewer than 1 in 4 youth meet federal guidelines. Children in rural areas from low socioeconomic (SES)…”
Get full text

Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations by Hobson, James J, Curley, Paul, Savage, Alison C, Al-khouja, Amer, Siccardi, Marco, Flexner, Charles, Meyers, Caren Freel, Owen, Andrew, Rannard, Steve P

“…The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel…”
Get full text

Exploring the Role of Academic Development in Supporting Tertiary Educators’ Well-Being: The Case of Online Consultations at UniSA by Strambi, Antonella, Hobson, James E, Baldock, Katherine, Janssen, Amanda

“…In this practice report, we posit that academic development encompasses more than improving and developing courses; it offers a space for tertiary educators to…”
Get full text

Exploring the role of academic development in Supporting Tertiary Educators' well-being: The case of online consultations at UniSA. 'A practice report' by Antonella Strambi, James E Hobson, Katherine Baldock, Amanda Janssen

“…In this practice report, we posit that academic development encompasses more than improving and developing courses; it offers a space for tertiary educators to…”
Get full text

Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents by Hernandes, Marcelo Zaldini, Rabello, Marcelo Montenegro, Leite, Ana Cristina Lima, Cardoso, Marcos Veríssimo Oliveira, Moreira, Diogo Rodrigo Magalhaes, Brondani, Dalci José, Simone, Carlos Alberto, Reis, Luiza Campos, Souza, Marina Assis, Pereira, Valéria Rego Alves, Ferreira, Rafaela Salgado, McKerrow, James Hobson

“…Optimization of antichagasic structures: thiazolylhydrazones represent a class of compounds that exhibit powerful trypanocidal properties, as confirmed by in…”
Get full text

Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate by Moss, Darren M, Domanico, Paul, Watkins, Melynda, Park, Seonghee, Randolph, Ryan, Wring, Steve, Rajoli, Rajith Kumar Reddy, Hobson, James, Rannard, Steve, Siccardi, Marco, Owen, Andrew

“…Tenofovir disoproxil fumarate (TDF), a prodrug of tenofovir, has oral bioavailability (25%) limited by intestinal transport (P-glycoprotein), and intestinal…”
Get full text