Search Results - "Hobl, Eva‐Luise"

Morphine Decreases Clopidogrel Concentrations and Effects: A Randomized, Double-Blind, Placebo-Controlled Trial by HOBL, Eva-Luise, STIMPFL, Thomas, EBNER, Josef, SCHOERGENHOFER, Christian, DERHASCHNIG, Ulla, SUNDER-PLASSMANN, Raute, JILMA-STOHLAWETZ, Petra, MANNHALTER, Christine, POSCH, Martin, JILMA, Bernd

“…This study sought to examine the possible drug-drug interactions between clopidogrel and morphine. Because morphine-the recommended treatment for pain of…”
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Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers by Hobl, Eva-Luise, Reiter, Birgit, Schoergenhofer, Christian, Schwameis, Michael, Derhaschnig, Ulla, Kubica, Jacek, Stimpfl, Thomas, Jilma, Bernd

“…Background Our recent drug interaction trial with clopidogrel shows that morphine decreases the concentrations and pharmacodynamic effects of clopidogrel,…”
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Clopidogrel in Critically Ill Patients by Schoergenhofer, Christian, Hobl, Eva‐Luise, Schellongowski, Peter, Heinz, Gottfried, Speidl, Walter S., Siller‐Matula, Jolanta M., Schmid, Monika, Sunder‐Plaßmann, Raute, Stimpfl, Thomas, Hackl, Matthias, Jilma, Bernd

“…Only limited data are available regarding the treatment of critically ill patients with clopidogrel. This trial investigated the effects and the drug…”
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Pharmacokinetic Modeling of Morphine’s Effect on Plasma Concentrations of Ticagrelor and Its Metabolite in Healthy Volunteers by Buszko, Katarzyna, Kubica, Krystian, Hobl, Eva-Luise, Adamski, Piotr, Wnuk, Kacper, Jilma, Bernd, Kubica, Jacek

“…This study aimed to build a mathematical model describing the pharmacokinetics of ticagrelor and its active metabolite (AR-C124910XX) in a stable setting with…”
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Abciximab as a bridging strategy to overcome morphine–prasugrel interaction in STEMI patients by Siller‐Matula, Jolanta M., Specht, Simon, Kubica, Jacek, Alexopoulos, Dimitrios, De Caterina, Raffaele, Hobl, Eva‐Luise, Jilma, Bernd, Christ, Günter, Lang, Irene M.

“…Objective The present study investigated whether the glycoprotein (GP)IIb/IIIa receptor blocker abciximab might be a successful bridging strategy to achieve…”
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Reversal strategy in antagonizing the P2Y12-inhibitor ticagrelor by Hobl, Eva-Luise, Derhaschnig, Ulla, Firbas, Christa, Schoergenhofer, Christian, Schwameis, Michael, Jilma, Bernd

“…Background Patients on antiplatelet therapy have a higher incidence of bleeding complications. Reversal of antiplatelet drug effects is an important issue at…”
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Acute Limb Ischemia after Intake of the Phenylethylamine Derivate NBOMe by Wadowski, Patricia P, Giurgea, Georgiana-Aura, Schlager, Oliver, Luf, Anton, Gremmel, Thomas, Hobl, Eva-Luise, Unterhumer, Sylvia, Löffler-Stastka, Henriette, Koppensteiner, Renate

“…: N-(2-methoxy) benzyl-phenethylamine (NBOMe) derivatives have a high affinity to the serotonin receptor 2A and emerged as new psychedelic agents. We report…”
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Acetylsalicylic acid in critically ill patients: a cross‐sectional and a randomized trial by Schoergenhofer, Christian, Hobl, Eva‐Luise, Schwameis, Michael, Gelbenegger, Georg, Staudinger, Thomas, Heinz, Gottfried, Speidl, Walter S., Zauner, Christian, Reiter, Birgit, Lang, Irene, Jilma, Bernd

“…Background Despite decades of clinical use, the pharmacokinetics and the effects of acetylsalicylic acid (ASA) in critically ill patients remain ill‐defined…”
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Absorption kinetics of low-dose chewable aspirin - implications for acute coronary syndromes by Hobl, Eva-Luise, Schmid, Rainer W., Stimpfl, Thomas, Ebner, Josef, Jilma, Bernd

“…Background This study describes the implications of the pharmacokinetics of low‐dose chewable aspirin for acute coronary syndromes. Current guidelines…”
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Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by isocratic high-pressure liquid chromatography with post-column hydrolysis and fluorescence detection by Hobl, Eva-Luise, Jilma, Bernd, Ebner, Josef, Schmid, Rainer W.

“…ABSTRACT A selective, sensitive and rapid high‐performance liquid chromatography method with post‐column hydrolysis and fluorescence detection was developed…”
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Comparison of a new ELISA‐based with the flow cytometric assay for vasodilator‐associated stimulated phosphoprotein phosphorylation to assess P2Y12‐inhibition after ticagrelor intake by Hobl, Eva‐Luise, Jilma, Bernd, Derhaschnig, Ulla, Schoergenhofer, Christian, Schwameis, Michael, Jilma‐Stohlawetz, Petra

“…Background Ticagrelor is a P2Y12 receptor antagonist, with superior effects but also ensuing enhanced bleeding risk as compared to clopidogrel. Determination…”
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A Randomized, Double-Blind, Parallel, Single-Site Pilot Trial to Compare Two Different Starting Doses of Methotrexate in Methotrexate-Naïve Adult Patients with Rheumatoid Arthritis by Hobl, Eva-Luise, PhD, Mader, Robert M., PhD, Jilma, Bernd, MD, Duhm, Bernhard, MD, Mustak, Monika, MD, Bröll, Hans, MD, Högger, Petra, PhD, Erlacher, Ludwig, MD

“…Abstract Background Methotrexate (MTX) is a cornerstone in the treatment of rheumatoid arthritis. Despite its widespread use, expert opinions differ about the…”
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Morphine Decreases Clopidogrel Concentrations and Effects by Hobl, Eva-Luise, PhD, Stimpfl, Thomas, PhD, Ebner, Josef, Schoergenhofer, Christian, MD, Derhaschnig, Ulla, MD, Sunder-Plassmann, Raute, MD, Jilma-Stohlawetz, Petra, MD, Mannhalter, Christine, PhD, Posch, Martin, PhD, Jilma, Bernd, MD

“…Objectives This study sought to examine the possible drug–drug interactions between clopidogrel and morphine. Background Because morphine—the recommended…”
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Tecarfarin: A Novel Vitamin K Antagonist by Hobl, Eva-Luise, Jilma, Bernd

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Towards the development of specific antidotes: Idarucizumab for reversal of dabigatran effects by Hobl, Eva-Luise, Jilma, Bernd

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Morphine interaction with prasugrel: a double-blind, cross-over trial in healthy volunteers by Hobl, Eva-Luise, Reiter, Birgit, Schoergenhofer, Christian, Schwameis, Michael, Derhaschnig, Ulla, Lang, Irene Marthe, Stimpfl, Thomas, Jilma, Bernd

“…Background Morphine decreases the concentrations and effects of clopidogrel, which could lead to treatment failure in myocardial infarction. Objectives To…”
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Impact of morphine on antiplatelet effects of oral P2Y12 receptor inhibitors by Kubica, Jacek, Kubica, Aldona, Jilma, Bernd, Adamski, Piotr, Hobl, Eva-Luise, Navarese, Eliano Pio, Siller-Matula, Jolanta Maria, Dąbrowska, Anita, Fabiszak, Tomasz, Koziński, Marek, Gurbel, Paul Alfred

“…Abstract Morphine and P2Y12 receptor inhibitors are both recommended in patients with acute myocardial infarction. Morphine may impede gastrointestinal…”
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Prasugrel in critically ill patients by Schoergenhofer, Christian, Hobl, Eva-Luise, Staudinger, Thomas, Speidl, Walter S, Heinz, Gottfried, Siller-Matula, Jolanta, Zauner, Christian, Reiter, Birgit, Kubica, Jacek, Jilma, Bernd

“…While prasugrel is indicated for the treatment of myocardial infarction, its effects in the most severely affected patients requiring intensive care is…”
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Potent irreversible P2Y12 inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial by Schoergenhofer, Christian, Schwameis, Michael, Hobl, Eva-Luise, Ay, Cihan, Key, Nigel S, Derhaschnig, Ulla, Jilma, Bernd, Spiel, Alexander O

“…Platelets play an important role in the activation of coagulation. P2Y12 receptor inhibition may be beneficial in inflammatory states. Prasugrel, a potent…”
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A short-chain methotrexate polyglutamate as outcome parameter in rheumatoid arthritis patients receiving methotrexate by HOBL, E.-L, JILMA, B, ERLACHER, L, DUHM, B, MUSTAK, M, BRÖLL, H, HÖGGER, P, RIZOVSKI, B, MADER, R. M

“…Methotrexate (MTX) is a cornerstone in the treatment of rheumatoid arthritis (RA). Although in general MTX is very effective, the major drawback is the large…”
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