Search Results - "Hoberman, AM"
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Effects of Thalidomide on Developmental, Peri- and Postnatal Function in Female New Zealand White Rabbits and Offspring
Published in Toxicological sciences (01-10-2004)“…The present study determined effects of thalidomide on three successive generations of New Zealand White rabbits after oral dosing to F0 maternal rabbits…”
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Effects of thalidomide on reproductive function and early embryonic development in male and female New Zealand white rabbits
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01-02-2004)“…BACKGROUND: The present work was performed to determine the effect of thalidomide exposure on reproductive function and early embryonic development. METHODS:…”
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OECD 414 Supplementary Prenatal Developmental Toxicity Study of Sodium Molybdate Dihydrate in the Rat and Benchmark Dose Evaluation
Published in Reproductive toxicology (Elmsford, N.Y.) (01-09-2023)“…In a continuing investigation of the potential for reproductive and developmental toxicity of molybdenum (Mo), consequent to the previous published OECD…”
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Considerations for occupational risk management during pregnancy: A summary of a continuing education course
Published in Toxicology and industrial health (01-11-2024)“…Women comprise approximately 40% of the global workforce, and many women continue to work during pregnancy. Although occupational exposure limit values (OELVs)…”
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Biodisposition of dibromoacetic acid (DBA) and bromodichloromethane (BDCM) administered to rats and rabbits in drinking water during range-finding reproduction and developmental toxicity studies
Published in International journal of toxicology (01-07-2001)“…Dibromoacetic acid (DBA) and bromodichloromethane (BDCM), by-products of chlorine disinfection of water, were provided in drinking water in range-finding…”
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Juvenile animal toxicity study designs to support pediatric drug development
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01-12-2009)“…The objective of juvenile animal toxicity studies of pharmaceuticals is to obtain safety data, including information on the potential for adverse effects on…”
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Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos
Published in Toxicological sciences (01-10-2000)“…Pregnant Sprague-Dawley rats were given chlorpyrifos (O:, O-diethyl-O:-[3,5,6-trichloro-2-pyridinyl] phosphorothioate; CPF) in corn oil by gavage from…”
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SEXUAL MATURATION DATA FOR CRL SPRAGUE-DAWLEY RATS: CRITERIA AND CONFOUNDING FACTORS
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-01-2002)“…ABSTRACT Background: Considerable concern exists in the scientific community regarding potential effects of endocrine disruptive or modulating environmental…”
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The Toxicity Profile of Hydrolyzed Aqueous Olive Pulp Extract
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-01-2004)“…The toxicity profile of HIDROX™ (Hydrolyzed Aqueous Olive Pulp Extract; OPE) was characterized in a series of toxicology studies. A limit dosage of 2000 mg kg…”
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The perinatal and postnatal toxicity of d-methylphenidate and d, l-methylphenidate in rats
Published in Reproductive toxicology (Elmsford, N.Y.) (01-07-2002)“…d-Methylphenidate is an enantiomer of d, l-methylphenidate and was developed as an improved treatment for attention deficit hyperactivity disorder (ADHD) in…”
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D-methylphenidate and D,L-methylphenidate are not developmental toxicants in rats and rabbits
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01-04-2003)“…BACKGROUND: D,L‐threo‐Methylphenidate (D,L‐MPH) is marketed currently for attention deficit hyperactivity disorder in children. D‐threo‐methylphenidate…”
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Developmental toxicity studies of four fragrances in rats
Published in Toxicology letters (20-12-1999)“…Four fragrances, 6-acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN), 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-γ-2-benzopyran (HHCB), musk ketone and…”
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Oral (Drinking Water) Two-Generation Reproductive Toxicity Study of Dibromoacetic Acid (DBA) in Rats
Published in International journal of toxicology (01-07-2002)“…In a two-generation study of dibromoacetic acid (DBA), Crl SD rats (30 rats/sex/group/generation) were provided DBA in drinking water at 0 (reverse…”
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Evaluation of the Developmental Toxicity of α-Methyl-3,4-Methylene-Dioxyhydrocinnamic Aldehyde in Rats
Published in International journal of toxicology (01-03-2006)“…The developmental toxicity of α-methyl-3,4-methylene-dioxyhydrocinnamic aldehyde (MMDHCA), a widely used fragrance ingredient, was evaluated for developmental…”
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Photocarcinogenesis: measuring the reproducibility of a biologic response to ultraviolet radiation exposure in mice
Published in Frontiers in bioscience (01-01-2003)“…New drugs undergo safety evaluations of many types. For some drugs, a photocarcinogenesis study forms one of the elements in the overall toxicology package…”
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A Study of the Developmental Toxicity Potential of Pentachlorophenol in the Rat
Published in International journal of toxicology (01-11-2001)“…Pentachlorophenol (penta, CAS #87–86–5) is primarily used as a wood preservative. As part of the USEPA pesticide reregistration process, the developmental…”
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Oral (Drinking Water) Two-Generation Reproductive Toxicity Study of Bromodichloromethane (BDCM) in Rats
Published in International journal of toxicology (01-03-2002)“…Bromodichloromethane (BDCM) was tested for reproductive toxicity in a two-generation study in CRL SD rats. Thirty rats/sex/group/generation were continuously…”
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Oral (Gavage) Two-Generation (One Litter Per Generation) Reproduction Study of Pentachlorophenol (Penta) in Rats
Published in International journal of toxicology (01-07-2002)“…The potential for pentachlorophenol (penta) to induce general and reproductive/developmental toxicity was evaluated in Crl Sprague-Dawley rats, employing a…”
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Oral (drinking water) developmental toxicity studies of bromodichloromethane (BDCM) in rats and rabbits
Published in International journal of toxicology (01-07-2001)“…Crl:CD(SD)IGS BR VAF/Plus (Crl SD) rats and Hra(NZW) SPF rabbits were tested for potential developmental toxicity from bromodichloromethane (BDCM) provided…”
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Erratum to “Developmental toxicity studies of four fragrances in rats”: [Toxicol. Lett. 111 (1-2) (1999) 169-174]
Published in Toxicology letters (20-12-2000)Get full text
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