Search Results - "Hobdey, Sarah E."
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Distinct roles of N- and O-glycans in cellulase activity and stability
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2017)“…In nature, many microbes secrete mixtures of glycoside hydrolases, oxidoreductases, and accessory enzymes to deconstruct polysaccharides and lignin in plants…”
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2
Engineering enhanced cellobiohydrolase activity
Published in Nature communications (22-03-2018)“…Glycoside Hydrolase Family 7 cellobiohydrolases (GH7 CBHs) catalyze cellulose depolymerization in cellulolytic eukaryotes, making them key discovery and…”
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3
Predicting Enzyme Adsorption to Lignin Films by Calculating Enzyme Surface Hydrophobicity
Published in The Journal of biological chemistry (25-07-2014)“…The inhibitory action of lignin on cellulase cocktails is a major challenge to the biological saccharification of plant cell wall polysaccharides. Although the…”
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4
Liposomes Prevent In Vitro Hemolysis Induced by Streptolysin O and Lysenin
Published in Membranes (Basel) (18-05-2021)“…The need for alternatives to antibiotics in the fight against infectious diseases has inspired scientists to focus on antivirulence factors instead of the…”
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5
Conversion of levoglucosan and cellobiosan by Pseudomonas putida KT2440
Published in Metabolic engineering communications (01-12-2016)“…Pyrolysis offers a straightforward approach for the deconstruction of plant cell wall polymers into bio-oil. Recently, there has been substantial interest in…”
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6
Streptococcus pyogenes NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O
Published in Microorganisms (Basel) (21-07-2022)“…Necrotizing soft tissue infections caused by Streptococcus pyogenes (group A streptococcus [GAS]) are characterized by rapid and extensive necrosis of fascia…”
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7
Poliovirus Polymerase Residue 5 Plays a Critical Role in Elongation Complex Stability
Published in Journal of Virology (01-08-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enrichment of Antigen-Specific Class-Switched B Cells from Individuals Naturally Immunized by Infection with Group A Streptococcus
Published in mSphere (06-11-2019)“…The low frequency of circulating antigen-specific memory B cells is a considerable obstacle in the discovery and development of human monoclonal antibodies for…”
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The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure
Published in RNA (Cambridge) (01-12-2009)“…The 5'-end of the flavivirus genome harbors a methylated (m7)GpppA(2'OMe) cap structure, which is generated by the virus-encoded RNA triphosphatase, RNA…”
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10
Characterization of Paeniclostridium sordellii Metalloproteinase-1 in vitro and in an experimental model of infection
Published in Anaerobe (01-10-2022)“…Paeniclostridium sordellii is a pathogen that causes rapidly fatal infections characterized by severe edema, extreme leukemoid reaction and lack of an innate…”
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Subinhibitory Dalbavancin Attenuates Exotoxin Production from Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus In Vitro
Published in Antimicrobial agents and chemotherapy (01-11-2017)“…This study investigated the effects of subinhibitory doses of the lipoglycopeptide antibiotic dalbavancin on toxin production toxin production levels were…”
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12
Biochemical and Structural Characterizations of Two Dictyostelium Cellobiohydrolases from the Amoebozoa Kingdom Reveal a High Level of Conservation between Distant Phylogenetic Trees of Life
Published in Applied and environmental microbiology (01-06-2016)“…Glycoside hydrolase family 7 (GH7) cellobiohydrolases (CBHs) are enzymes commonly employed in plant cell wall degradation across eukaryotic kingdoms of life,…”
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13
Determinants of Histone H4 N-terminal Domain Function during Nucleosomal Array Oligomerization: ROLES OF AMINO ACID SEQUENCE, DOMAIN LENGTH, AND CHARGE DENSITY
Published in The Journal of biological chemistry (19-06-2009)“…Mg²⁺-dependent oligomerization of nucleosomal arrays is correlated with higher order folding transitions that stabilize chromosome structure beyond the 30-nm…”
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14
New perspective on glycoside hydrolase binding to lignin from pretreated corn stover
Published in Biotechnology for biofuels (18-12-2015)“…Non-specific binding of cellulases to lignin has been implicated as a major factor in the loss of cellulase activity during biomass conversion to sugars. It is…”
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15
Determinants of Histone H4 N-terminal Domain Function during Nucleosomal Array Oligomerization
Published in The Journal of biological chemistry (19-06-2009)“…Mg2+-dependent oligomerization of nucleosomal arrays is correlated with higher order folding transitions that stabilize chromosome structure beyond the 30-nm…”
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16
constitutive expression system for glycosyl hydrolase family 7 cellobiohydrolases in Hypocrea jecorina
Published in Biotechnology for biofuels (18-03-2015)“…BACKGROUND: One of the primary industrial-scale cellulase producers is the ascomycete fungus, Hypocrea jecorina, which produces and secretes large quantities…”
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17
High temperature pre-digestion of corn stover biomass for improved product yields
Published in Biotechnology for biofuels (2014)“…INTRODUCTION: The efficient conversion of lignocellulosic feedstocks remains a key step in the commercialization of biofuels. One of the barriers to…”
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18
Subinhibitory Dalbavancin Attenuates Exotoxin Production from Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureusIn Vitro
Published in Antimicrobial agents and chemotherapy (24-10-2017)“…This study investigated the effects of subinhibitory doses of the lipoglycopeptide antibiotic dalbavancin on Staphylococcus aureus toxin production in vitro…”
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Journal Article -
19
IStreptococcus pyogenes/I NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O
Published in Microorganisms (Basel) (21-07-2022)“…Necrotizing soft tissue infections caused by Streptococcus pyogenes (group A streptococcus [GAS]) are characterized by rapid and extensive necrosis of fascia…”
Get full text
Journal Article -
20
Distinct roles of N- and O-glycans in cellulase activity and stability
Published in Proceedings of the National Academy of Sciences - PNAS (11-12-2017)“…In nature, many microbes secrete mixtures of glycoside hydrolases, oxidoreductases, and accessory enzymes to deconstruct polysaccharides and lignin in plants…”
Get full text
Journal Article