Search Results - "Hobbs, M"

Molecular regulation of spermatogonial stem cell renewal and differentiation by Mäkelä, Juho-Antti, Hobbs, Robin M

“…The intricate molecular and cellular interactions between spermatogonial stem cells (SSCs) and their cognate niche form the basis for life-long sperm…”
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Psychotic-like experiences in a community sample of 8000 children aged 9 to 11 years: an item response theory analysis by Laurens, K R, Hobbs, M J, Sunderland, M, Green, M J, Mould, G L

“…Psychotic-like experiences (PLEs) in the general population are common, particularly in childhood, and may constitute part of a spectrum of normative…”
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Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State by Garcia-Cao, Isabel, Song, Min Sup, Hobbs, Robin M., Laurent, Gaelle, Giorgi, Carlotta, de Boer, Vincent C.J., Anastasiou, Dimitrios, Ito, Keisuke, Sasaki, Atsuo T., Rameh, Lucia, Carracedo, Arkaitz, Vander Heiden, Matthew G., Cantley, Lewis C., Pinton, Paolo, Haigis, Marcia C., Pandolfi, Pier Paolo

“…Decremental loss of PTEN results in cancer susceptibility and tumor progression. PTEN elevation might therefore be an attractive option for cancer prevention…”
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PeriPy - A high performance OpenCL peridynamics package by Boys, B., Dodwell, T.J., Hobbs, M., Girolami, M.

“…This paper presents a lightweight, open-source and high-performance python package for solving peridynamics problems in solid mechanics. The development of…”
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Emotional disorders: cluster 4 of the proposed meta-structure for DSM-V and ICD-11 by Goldberg, D P, Krueger, R F, Andrews, G, Hobbs, M J

“…The extant major psychiatric classifications DSM-IV, and ICD-10, are atheoretical and largely descriptive. Although this achieves good reliability, the…”
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Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1 by Hobbs, Robin M., Seandel, Marco, Falciatori, Ilaria, Rafii, Shahin, Pandolfi, Pier Paolo

“…Hyperactivity of mTORC1, a key mediator of cell growth, leads to stem cell depletion, although the underlying mechanisms are poorly defined. Using…”
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The Apache Point Observatory Catalog of Optical Diffuse Interstellar Bands by Fan, Haoyu, Hobbs, L. M., Dahlstrom, Julie A., Welty, Daniel E., York, Donald G., Rachford, Brian, Snow, Theodore P., Sonnentrucker, Paule, Baskes, Noah, Zhao, Gang

“…Aiming for a new and more comprehensive DIB catalog between 4000 and 9000 , we revisited the Atlas Catalog based on the observations of HD 183143 and HD…”
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Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function by Papa, Antonella, Wan, Lixin, Bonora, Massimo, Salmena, Leonardo, Song, Min Sup, Hobbs, Robin M., Lunardi, Andrea, Webster, Kaitlyn, Ng, Christopher, Newton, Ryan H., Knoblauch, Nicholas, Guarnerio, Jlenia, Ito, Keisuke, Turka, Laurence A., Beck, Andy H., Pinton, Paolo, Bronson, Roderick T., Wei, Wenyi, Pandolfi, Pier Paolo

“…PTEN dysfunction plays a crucial role in the pathogenesis of hereditary and sporadic cancers. Here, we show that PTEN homodimerizes and, in this active…”
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DSM-IV post-traumatic stress disorder among World Trade Center responders 11-13 years after the disaster of 11 September 2001 (9/11) by Bromet, E J, Hobbs, M J, Clouston, S A P, Gonzalez, A, Kotov, R, Luft, B J

“…Post-traumatic symptomatology is one of the signature effects of the pernicious exposures endured by responders to the World Trade Center (WTC) disaster of 11…”
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Functional Antagonism between Sall4 and Plzf Defines Germline Progenitors by Hobbs, Robin M., Fagoonee, Sharmila, Papa, Antonella, Webster, Kaitlyn, Altruda, Fiorella, Nishinakamura, Ryuichi, Chai, Li, Pandolfi, Pier Paolo

“…Transcription factors required for formation of embryonic tissues often maintain their expression in adult stem cell populations, but whether their function…”
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Unhealthy environments are associated with adverse mental health and psychological distress: Cross-sectional evidence from nationally representative data in New Zealand by Hobbs, M., Kingham, S., Wiki, J., Marek, L., Campbell, M.

“…This study combines data on the location of health-constraining ‘bads’ (i: fast-food outlets, ii: takeaway outlets, iii: dairy outlets and convenience stores,…”
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Investigating the spatial and temporal variation of vape retailer provision in New Zealand: A cross-sectional and nationwide study by Waterman, I., Marek, L., Ahuriri-Driscoll, A., Mohammed, J., Epton, M., Hobbs, M.

“…Smoking rates have decreased in Aotearoa New Zealand in recent years however, vaping has shown a dramatic upward trend especially among young people; up to 10%…”
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DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia by Legrand, Julien M. D., Chan, Ai-Leen, La, Hue M., Rossello, Fernando J., Änkö, Minna-Liisa, Fuller-Pace, Frances V., Hobbs, Robin M.

“…Mammalian spermatogenesis is sustained by mitotic germ cells with self-renewal potential known as undifferentiated spermatogonia. Maintenance of…”
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Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming by Moreau, Thomas, Evans, Amanda L., Vasquez, Louella, Tijssen, Marloes R., Yan, Ying, Trotter, Matthew W., Howard, Daniel, Colzani, Maria, Arumugam, Meera, Wu, Wing Han, Dalby, Amanda, Lampela, Riina, Bouet, Guenaelle, Hobbs, Catherine M., Pask, Dean C., Payne, Holly, Ponomaryov, Tatyana, Brill, Alexander, Soranzo, Nicole, Ouwehand, Willem H., Pedersen, Roger A., Ghevaert, Cedric

“…The production of megakaryocytes (MKs)—the precursors of blood platelets—from human pluripotent stem cells (hPSCs) offers exciting clinical opportunities for…”
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The environment an adult resides within is associated with their health behaviours, and their mental and physical health outcomes: a nationwide geospatial study by Hobbs, M., Milfont, T.L., Marek, L., Yogeeswaran, K., Sibley, C.G.

“…The determinants of health behaviours and health outcomes are multifaceted and the surrounding environment is increasingly considered as an important…”
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Examining spatial variation for immunisation coverage in pregnant women: A nationwide and geospatial retrospective cohort study in Aotearoa New Zealand by Hobbs, M., Marek, L., Young, A., Willing, E., Dawson, P., McIntyre, P.

“…Maternal influenza and pertussis immunisation is crucial for protecting mothers during pregnancy and their babies in the first weeks of life against severe…”
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Examining longitudinal associations between the recreational physical activity environment, change in body mass index, and obesity by age in 8864 Yorkshire Health Study participants by Hobbs, M., Griffiths, C., Green, M.A., Christensen, A., McKenna, J.

“…The environment may lead to lower body mass index (BMI) and obesity risk by providing opportunities to be physically active. However, while intuitively…”
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Distributional justice and climate risk assessment: An analysis of disparities within direct and indirect risk by Anderson, M J, Conrow, L, Hobbs, M, Paulik, R, Blackett, P, Logan, T

“…Climate change and natural hazard risk assessments often overlook indirect impacts, leading to a limited understanding of the full extent of risk and the…”
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RNA processing in the male germline: Mechanisms and implications for fertility by Legrand, Julien M.D., Hobbs, Robin M.

“…Mammalian spermatogenesis is a tightly coordinated process that gives rise to mature spermatozoa capable of fertilising an ovum during sexual reproduction. A…”
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Biomarker Validation of Reports of Recent Sexual Activity: Results of a Randomized Controlled Study in Zimbabwe by Minnis, Alexandra M., Steiner, Markus J., Gallo, Maria F., Warner, Lee, Hobbs, Marcia M., van der Straten, Ariane, Chipato, Tsungai, Macaluso, Maurizio, Padian, Nancy S.

“…Challenges in the accurate measurement of sexual behavior in human immunodeficiency virus (HIV) prevention research are well documented and have prompted…”
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