Search Results - "Hobbs, Kristen"
-
1
Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30
Published in PLoS pathogens (01-02-2018)“…HIV-1-infected cells persist indefinitely despite the use of combination antiretroviral therapy (ART), and novel therapeutic strategies to target and purge…”
Get full text
Journal Article -
2
A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads
Published in Virology (New York, N.Y.) (01-07-2017)“…Abstract Assays that can verify full viral eradication are essential in the context of achieving a cure for HIV/AIDS. In vitro quantitative viral out growth…”
Get full text
Journal Article -
3
Human Herpes Virus 8 in HIV-1 infected individuals receiving cancer chemotherapy and stem cell transplantation
Published in PloS one (10-05-2018)“…Human Herpes Virus 8 (HHV8) can cause Kaposi's Sarcoma (KS) in immunosuppressed individuals. However, little is known about the association between…”
Get full text
Journal Article -
4
A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size
Published in PLoS pathogens (01-11-2023)“…The major barrier to an HIV cure is the HIV reservoir: latently-infected cells that persist despite effective antiretroviral therapy (ART). There have been few…”
Get full text
Journal Article -
5
Multitarget, quantitative nanoplasmonic electrical field-enhanced resonating device (NE²RD) for diagnostics
Published in Proceedings of the National Academy of Sciences - PNAS (11-08-2015)“…Recent advances in biosensing technologies present great potential for medical diagnostics, thus improving clinical decisions. However, creating a label-free…”
Get full text
Journal Article -
6
Human Immunodeficiency Virus Type 1 Persistence Following Systemic Chemotherapy for Malignancy
Published in The Journal of infectious diseases (15-07-2017)“…Background. Systemic chemotherapies for various malignancies have been shown to significantly, yet transiently, decrease numbers of CD4+ T lymphocytes, a major…”
Get full text
Journal Article -
7
Advancing More Equitable Care Through the Development of a Health Equity Report Card
Published in Journal of the National Comprehensive Cancer Network (01-02-2023)“…The root causes of racial disparities in access to optimal cancer care and related cancer outcomes are complex, multifactorial, and not rooted in biology…”
Get more information
Journal Article -
8
High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay
Published in EBioMedicine (01-06-2017)“…Reactivation of latent viral reservoirs is on the forefront of HIV-1 eradication research. However, it is unknown if latency reversing agents (LRAs) increase…”
Get full text
Journal Article -
9
HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study
Published in PLoS medicine (07-11-2017)“…It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we studied 2…”
Get full text
Journal Article -
10
Rapid development of HIV elite control in a patient with acute infection
Published in BMC infectious diseases (18-09-2019)“…Elite controllers (EC), a small subset of the HIV-positive population (< 1%), suppress HIV viremia below the limit of quantification of clinical viral load…”
Get full text
Journal Article -
11
-
12
Correction to: Rapid development of HIV elite control in a patient with acute infection
Published in BMC infectious diseases (22-10-2019)“…After publication of the original article [1], we were notified in Table 1 a column should be removed…”
Get full text
Journal Article -
13
THE COMMUNICATION CONUNDRUM: WEIGHING THE NEED TO PROVE INTENT IN ERISA MISREPRESENTATION CLAIMS
Published in Emory law journal (01-01-2024)“…In 1974, Congress enacted the Employee Retirement Income Security Act (ERISA) to provide oversight to voluntary employee benefit plans in the private sector…”
Get full text
Journal Article -
14
NK-cell activation is associated with increased HIV transcriptional activity following allogeneic hematopoietic cell transplantation
Published in Blood advances (26-06-2018)“…•Graft-versus-host effects may lead to HIV-1 reactivation and cell death of infected pre-HCT CD4+ T cells.•Natural killer cell activation correlates with in…”
Get full text
Journal Article -
15
OA2-3 Small-molecule chemotherapeutic drugs reactivate HIV-1 via non-canonical pathways and modulate CD8 T cell response
Published in Journal of Virus Eradication (01-07-2017)Get full text
Journal Article -
16
Advancing equity in prostate cancer outcomes using community-facing navigation in the cancer continuum of care
Published in Journal of clinical oncology (01-10-2022)“…120 Background: According to the American Cancer Society, prostate cancer is the second most common cause of cancer death in Black men. Between 2014–2018, the…”
Get full text
Journal Article -
17
Abstract 12554: A Quality Improvement Program to Promote Assessment of Social Determinants of Health among Patients in an Urban Community Clinic
Published in Circulation (New York, N.Y.) (16-11-2021)“…IntroductionSocial determinants of health (SDoH) have been linked to poorer health outcomes and health disparities among patients (pts) with heart failure…”
Get full text
Journal Article -
18
Birds groom more in regions with higher parasite pressure: a comparison of temperate and subtropical American kestrels
Published in Animal behaviour (01-07-2023)“…Grooming behaviour, which maintains and cleans the integument, is a widespread behaviour of birds, mammals and arthropods. The extent to which grooming is…”
Get full text
Journal Article -
19
Promotion of prostate cancer screening equity: A quality improvement education initiative
Published in Journal of clinical oncology (01-10-2021)“…Abstract only 140 Background: Black men are disparately affected by prostate cancer (PC). They are more likely to develop PC and at an earlier age when the…”
Get full text
Journal Article -
20
Abstract P134: Selected Social Determinants Of Health And Hypertension For Patients Of An Urban Community Primary Care Clinic
Published in Hypertension (Dallas, Tex. 1979) (01-09-2021)“…BackgroundHypertension (HTN) is the most potent cardiovascular disease worldwide and a major public health concern in the U.S. Although Social Determinants of…”
Get full text
Journal Article