Search Results - "Hobbing, Katharine R."
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RASSF1A Deficiency Enhances RAS-Driven Lung Tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-05-2018)“…Mutant K-RAS has been shown to have both tumor-promoting and -suppressing functions, and growing evidence suggests that the RASSF family of tumor suppressors…”
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Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells
Published in BMC cancer (13-04-2018)“…Dysregulation of microRNA (miRNA) expression is associated with hallmarks of aggressive tumor phenotypes, e.g., enhanced cell growth, proliferation, invasion,…”
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The RASSF1A Tumor Suppressor Regulates XPA-Mediated DNA Repair
Published in Molecular and cellular biology (01-01-2015)“…RASSF1A may be the most frequently inactivated tumor suppressor identified in human cancer so far. It is a proapoptotic Ras effector and plays an important…”
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Abstract 1906: Inhibition of miR-186 and repression of aggressive prostate cancer phenotype using a metastatic cell model
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…MicroRNA (miR) dysregulation alters the expression of cancer related genes and contributes to disease states in many cancers. For example, ectopic miR-186…”
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miR‐186 suppresses cell proliferation and anchorage‐independence in a metastatic prostate cancer cell line
Published in The FASEB journal (01-04-2016)“…Abstract only MicroRNA (miR) dysregulation alters the expression of cancer related genes and contributes to disease states in many cancers. For example,…”
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Suppression of miR‐186 Attenuates Cellular Invasion, pAKT and β‐catenin in Metastatic Prostate Cancer Cell Models
Published in The FASEB journal (01-04-2018)“…Background MicroRNA (miR) dysregulation alters the expression of cancer related genes and contributes to disease states in many cancers. For example, ectopic…”
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Abstract 3085: MicroRNA-186 inhibition alters cell proliferation and colony formation in prostate cancer
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…MicroRNAs (miRs), key regulators of cancer-related genes, are dysregulated in many solid tumors, including prostate cancer. However, the role of miR-186 in…”
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