Search Results - "Hoang, Lynn N."

Molecular characterization of invasive and in situ squamous neoplasia of the vulva and implications for morphologic diagnosis and outcome by Tessier-Cloutier, Basile, Pors, Jennifer, Thompson, Emily, Ho, Julie, Prentice, Leah, McConechy, Melissa, Aguirre-Hernandez, Rosalia, Miller, Ruth, Leung, Samuel, Proctor, Lily, McAlpine, Jessica N., Huntsman, David G., Gilks, C. Blake, Hoang, Lynn N.

“…Human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC) is an aggressive clinical entity. Current diagnostic guidelines for premalignant…”
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Major p53 immunohistochemical patterns in in situ and invasive squamous cell carcinomas of the vulva and correlation with TP53 mutation status by Tessier-Cloutier, Basile, Kortekaas, Kim E., Thompson, Emily, Pors, Jennifer, Chen, Julia, Ho, Julie, Prentice, Leah M., McConechy, Melissa K., Chow, Christine, Proctor, Lily, McAlpine, Jessica N., Huntsman, David G., Gilks, C. Blake, Bosse, Tjalling, Hoang, Lynn N.

“…The recent literature has shown that vulvar squamous cell carcinoma (VSCC) can be stratified into two prognostically relevant groups based on human…”
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Utilization of p53 and p16 Immunohistochemistry in the Classification of Human Papillomavirus-Associated, p53 Wild-Type, and p53 Abnormal Oral Epithelial Dysplasia by Novack, Rachel, Chapman, Erin, Gao, Jiangyuan, Horst, Basil, Hoang, Lynn N, Ng, Tony L, Ko, Yen Chen Kevin

“…p53 immunohistochemistry (IHC) has recently been shown to be a clinically useful marker for predicting risk of progression to invasive squamous cell carcinoma…”
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c-KIT Analysis and Targeted Molecular Sequencing of Mesonephric Carcinomas of the Female Genital Tract by Pors, Jennifer, Ho, Julie, Prentice, Leah, Thompson, Emily, Cochrane, Dawn, Gibbard, Evan, Huntsman, David, Gilks, Blake, Hoang, Lynn N.

“…Mesonephric carcinoma is a rare malignancy, thought to derive from Wolffian remnants. To date, no targeted molecular therapeutic options have been identified…”
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Abnormal p53 Immunohistochemical Patterns Shed Light on the Aggressiveness of Oral Epithelial Dysplasia by Novack, Rachel, Zhang, Lewei, Hoang, Lynn N., Kadhim, Mohamad, Ng, Tony L., Poh, Catherine F., Kevin Ko, Yen Chen

“…The diagnosis of oral epithelial dysplasia is based on the degree of architectural and cytologic atypia in the squamous epithelium. The conventional grading…”
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Classification of Vulvar Squamous Cell Carcinoma and Precursor Lesions by p16 and p53 Immunohistochemistry: Considerations, Caveats, and an Algorithmic Approach by Yang, Hang, Almadani, Noorah, Thompson, Emily F., Tessier-Cloutier, Basile, Chen, Julia, Ho, Julie, Senz, Janine, McConechy, Melissa K., Chow, Christine, Ta, Monica, Cheng, Angela, Karnezis, Anthony, Huvila, Jutta, McAlpine, Jessica N., Gilks, Blake, Jamieson, Amy, Hoang, Lynn N.

“…There is emerging evidence that vulvar squamous cell carcinoma (VSCC) can be prognostically subclassified into 3 groups based on human papillomavirus (HPV) and…”
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Abnormal p53 Immunohistochemical Patterns Are Associated with Regional Lymph Node Metastasis in Oral Cavity Squamous Cell Carcinoma at Time of Surgery by Lin, Tami Yu-Yu, Liu, Kelly Yi Ping, Novack, Rachel, Mattu, Pushwant S., Ng, Tony L., Hoang, Lynn N., Prisman, Eitan, Poh, Catherine F., Ko, Yen Chen Kevin

“…Most (60%-80%) of the oral cavity invasive squamous cell carcinoma (OSCC) demonstrate molecular alterations in TP53. The presence of TP53 mutations in multiple…”
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p53-Abnormal “Fields of Dysplasia” in Human Papillomavirus–Independent Vulvar Squamous Cell Carcinoma Impacts Margins and Recurrence Risk by Thompson, Emily F., Wong, Richard W.C., Trevisan, Giorgia, Tessier-Cloutier, Basile, Almadani, Noorah, Chen, Julia, Cheng, Angela, Karnezis, Anthony, McConechy, Melissa K., Lum, Amy, Senz, Janine, McAlpine, Jessica N., Huntsman, David G., Gilks, Blake, Jamieson, Amy, Hoang, Lynn N.

“…Abnormal p53 (p53abn) immunohistochemical (IHC) staining patterns can be found in vulvar squamous cell carcinoma (VSCC) and differentiated vulvar…”
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The proteome of clear cell ovarian carcinoma by Ji, Jennifer X, Cochrane, Dawn R, Negri, Gian Luca, Colborne, Shane, Spencer Miko, Sandra E, Hoang, Lynn N, Farnell, David, Tessier‐Cloutier, Basile, Huvila, Jutta, Thompson, Emily, Leung, Samuel, Chiu, Derek, Chow, Christine, Ta, Monica, Köbel, Martin, Feil, Lucas, Anglesio, Michael, Goode, Ellen L, Bolton, Kelly, Morin, Gregg B, Huntsman, David G

“…Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial ovarian carcinoma. Late‐stage CCOC is not responsive to gold‐standard…”
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Squamous and Glandular Lesions of the Vulva and Vagina: What's New and What Remains Unanswered? by Wei, Kelly X, Hoang, Lynn N

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Should you repeat mismatch repair testing in cases of tumour recurrence? An evaluation of repeat mismatch repair testing by the use of immunohistochemistry in recurrent tumours of the gastrointestinal and gynaecological tracts by Aird, John J, Steel, Michael J, Chow, Christine, Ho, Julie, Wolber, Robert, Gilks, C Blake, Hoang, Lynn N, Schaeffer, David F

“…Aims The role of mismatch repair (MMR) testing has evolved from identifying Lynch syndrome patients to predicting response to immune checkpoint inhibitors…”
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Use of Immunohistochemical Markers (HNF-1β, Napsin A, ER, CTH, and ASS1) to Distinguish Endometrial Clear Cell Carcinoma From Its Morphologic Mimics Including Arias-Stella Reaction by Ji, Jennifer X, Cochrane, Dawn R, Tessier-Cloutier, Basile, Leung, Samuel, Cheng, Angela S, Chow, Christine, Gilks, Blake, Huntsman, David G, Hoang, Lynn N

“…The diagnosis of clear cell (CC) carcinoma of the endometrium can be challenging, especially when endometrioid (EC) and serous (SC) endometrial cancers exhibit…”
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Squamous and Glandular Lesions of the Vulva and Vagina by Wei, Kelly X., Hoang, Lynn N.

“…A number of changes have been introduced into the 5th Edition of the World Health Organization (WHO) Classification of squamous and glandular neoplasms of the…”
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Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type by Ji, Jennifer X, Cochrane, Dawn R, Tessier-Cloutier, Basile, Chen, Shary Yutin, Ho, Germain, Pathak, Khyatiben V, Alcazar, Isabel N, Farnell, David, Leung, Samuel, Cheng, Angela, Chow, Christine, Colborne, Shane, Negri, Gian Luca, Kommoss, Friedrich, Karnezis, Anthony, Morin, Gregg B, McAlpine, Jessica N, Gilks, C Blake, Weissman, Bernard E, Trent, Jeffrey M, Hoang, Lynn, Pirrotte, Patrick, Wang, Yemin, Huntsman, David G

“…Many rare ovarian cancer subtypes, such as small-cell carcinoma of the ovary, hypercalcemic type (SCCOHT), have poor prognosis due to their aggressive nature…”
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