Search Results - "Ho Cha, Seok"
-
1
Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney
Published in Journal of the American Society of Nephrology (01-04-2002)“…Recently, a family of multispecific organic anion transporters has been identified, and several isoforms have been reported. However, the physiologic and…”
Get full text
Journal Article -
2
Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules
Published in The Journal of pharmacology and experimental therapeutics (01-11-2005)“…A novel member of the organic anion transporter (OAT) family, Oat5 (Slc22a19), has been reported to transport a naturally occurring mycotoxin, ochratoxin A…”
Get more information
Journal Article -
3
Swedish amyloid precursor protein mutation increases cell cycle-related proteins in vitro and in vivo
Published in Journal of neuroscience research (15-08-2008)“…Reactivation of the cell cycle, including DNA replication, might play a major role in Alzheimer's disease. In this study, we report that the expressions of…”
Get full text
Journal Article -
4
Functional characterization of Plasmodium vivax hexose transporter 1
Published in Frontiers in cellular and infection microbiology (2023)“…is the most widely distributed human malaria parasite. The eradication of vivax malaria remains challenging due to transmission of drug-resistant parasite and…”
Get full text
Journal Article -
5
Synergistic production of interleukin-23 by dendritic cells derived from cord blood in response to costimulation with LPS and IL-12
Published in Journal of leukocyte biology (01-09-2009)“…IL‐23 secretion from stimulated DCs, dependent on ERK1/2 and p38 MAPK, caused an induction of memory interferon‐γ‐secreting T cells. This study was performed…”
Get full text
Journal Article -
6
Role of Mouse Organic Anion Transporter 3 (mOat3) as a Basolateral Prostaglandin E2 Transport Pathway
Published in Journal of Pharmacological Sciences (2007)“…Renal organic anion transporters play an important role in the handling of a number of endogenous and exogenous anionic substances in the kidney. In this…”
Get full text
Journal Article -
7
Molecular identification of a renal urate-anion exchanger that regulates blood urate levels
Published in Nature (London) (23-05-2002)“…Urate, a naturally occurring product of purine metabolism, is a scavenger of biological oxidants implicated in numerous disease processes, as demonstrated by…”
Get full text
Journal Article -
8
Development of a polymerase chain reaction applicable to rapid and sensitive detection of Clonorchis sinensis eggs in human stool samples
Published in Pathogens and global health (01-07-2013)“…Microscopic examination of eggs of parasitic helminths in stool samples has been the most widely used classical diagnostic method for infections, but tiny and…”
Get full text
Journal Article -
9
Geographical distribution and genetic diversity of Plasmodium vivax reticulocyte binding protein 1a correlates with patient antigenicity
Published in PLoS neglected tropical diseases (23-06-2022)“…Plasmodium vivax is the most widespread cause of human malaria. Recent reports of drug resistant vivax malaria and the challenge of eradicating the dormant…”
Get full text
Journal Article -
10
Identification of a kidney-specific mouse organic cation transporter like-1 (mOCTL1)
Published in Experimental & molecular medicine (31-12-2007)“…Organic ion transporters are expressed in various tissues that transport endogenous and exogenous compounds including their metabolites. There are organic…”
Get full text
Journal Article -
11
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
Published in Molecular pharmacology (01-05-2001)“…A cDNA encoding a multispecific organic anion transporter 3 (hOAT3) was isolated from a human kidney cDNA library. The hOAT3 cDNA consisted of 2179 base pairs…”
Get more information
Journal Article -
12
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines
Published in Biochimica et biophysica acta (01-10-2001)“…System L is a major nutrient transport system responsible for the transport of large neutral amino acids including several essential amino acids. We previously…”
Get full text
Journal Article -
13
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity
Published in Journal of the American Society of Nephrology (01-07-2002)“…In uremic patients, various uremic toxins are accumulated and exert various biologic effects on uremia. Indoxyl sulfate (IS) is one of uremic toxins that is…”
Get full text
Journal Article -
14
Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain
Published in The Journal of biological chemistry (07-05-1999)“…A cDNA encoding the new member of the multispecific organic anion transporter family, OAT3, was isolated by the reverse transcription-polymerase chain reaction…”
Get full text
Journal Article -
15
Characterization of methotrexate transport and its drug interactions with human organic anion transporters
Published in The Journal of pharmacology and experimental therapeutics (01-08-2002)“…Life-threatening drug interactions are known to occur between methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs), probenecid, and penicillin G. The…”
Get more information
Journal Article -
16
Induction of glioma apoptosis by microglia-secreted molecules: The role of nitric oxide and cathepsin B
Published in Biochimica et biophysica acta (01-11-2009)“…Microglia contributes significantly to brain tumor mass, particularly in astrocytic gliomas. Here, we examine the cytotoxic effects of soluble components…”
Get full text
Journal Article -
17
Human organic anion transporters and human organic cation transporters mediate renal antiviral transport
Published in The Journal of pharmacology and experimental therapeutics (01-03-2002)“…Renal excretion is an important elimination pathway for antiviral agents, such as acyclovir (ACV), ganciclovir (GCV), and zidovudine (AZT). The purpose of this…”
Get more information
Journal Article -
18
The multispecific organic anion transporter (OAT) family
Published in Pflügers Archiv (01-07-2000)“…Organic anion transporters play important roles in the elimination of a variety of endogenous substances, xenobiotics and their metabolites from the body…”
Get full text
Journal Article -
19
Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta
Published in The Journal of biological chemistry (11-02-2000)“…A cDNA encoding a novel multispecific organic anion transporter, OAT4, was isolated from a human kidney cDNA library. The OAT4 cDNA consisted of 2210 base…”
Get full text
Journal Article -
20
Expression Cloning of a Na+-independent Aromatic Amino Acid Transporter with Structural Similarity to H+/Monocarboxylate Transporters
Published in The Journal of biological chemistry (18-05-2001)“…A cDNA was isolated from rat small intestine by expression cloning which encodes a novel Na+-independent transporter for aromatic amino acids. When expressed…”
Get full text
Journal Article