Search Results - "Höppener, Jo W. M."

Amyloid Proteins and Peripheral Neuropathy by Asiri, Mohammed M H, Engelsman, Sjoukje, Eijkelkamp, Niels, Höppener, Jo W M

“…Painful peripheral neuropathy affects millions of people worldwide. Peripheral neuropathy develops in patients with various diseases, including rare familial…”
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The Multiple Endocrine Neoplasia Type 1 (MEN1) Tumor Suppressor Regulates Peroxisome Proliferator-Activated Receptor γ-Dependent Adipocyte Differentiation by Dreijerink, Koen M. A., Varier, Radhika A., van Beekum, Olivier, Jeninga, Ellen H., Höppener, Jo W. M., Lips, Cornelis J. M., Kummer, J. Alain, Kalkhoven, Eric, Timmers, H. T. Marc

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Impaired Processing of Human Pro-Islet Amyloid Polypeptide Is Not a Causative Factor for Fibril Formation or Membrane Damage in Vitro by Khemtémourian, Lucie, Lahoz Casarramona, Gemma, Suylen, Dennis P. L, Hackeng, Tilman M, Meeldijk, Johannes D, de Kruijff, Ben, Höppener, Jo W. M, Killian, J. Antoinette

“…Human islet amyloid polypeptide (hIAPP) forms amyloid fibrils in pancreatic islets of patients with type 2 diabetes mellitus (DM2). hIAPP is synthesized by…”
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Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane by Engel, Maarten F.M, Khemtémourian, Lucie, Kleijer, Cécile C, Meeldijk, Hans J.D, Jacobs, Jet, Verkleij, Arie J, de Kruijff, Ben, Killian, J. Antoinette, Höppener, Jo W.M

“…Fibrillar protein deposits (amyloid) in the pancreatic islets of Langerhans are thought to be involved in death of the insulin-producing islet β cells in type…”
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Pheochromocytoma in Von Hippel-Lindau Disease by Hes, Frederik J., Höppener, Jo W. M., Lips, Cornelis J. M.

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The spectrum of carcinoid tumours and carcinoid syndromes by Lips, Cornelis J M, Lentjes, Eef G W M, Höppener, Jo W M

“…Carcinoids are neuroendocrine tumours of the gut which may also be found in the bronchus, pancreatic islets and retroperitoneum. They probably arise from…”
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Recent Insights in Islet Amyloid Polypeptide-Induced Membrane Disruption and Its Role in β-Cell Death in Type 2 Diabetes Mellitus by Khemtémourian, Lucie, Antoinette Killian, J., Höppener, Jo W. M., Engel, Maarten F. M.

“…The presence of fibrillar protein deposits (amyloid) of human islet amyloid polypeptide (hIAPP) in the pancreatic islets of Langerhans is thought to be related…”
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Tissue Selectivity in Multiple Endocrine Neoplasia Type 1-Associated Tumorigenesis by GRACANIN, Ana, DREIJERINK, Koen M. A, VAN DER LUIJT, Rob B, LIPS, Cornelis J. M, HÖPPENER, Jo W. M

“…The phenotype of the multiple endocrine neoplasia type 1 (MEN1) syndrome cannot be explained solely by the expression pattern of the predisposing gene MEN1 and…”
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P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development by van Veelen, Wendy, Klompmaker, Rob, Gloerich, Martijn, van Gasteren, Carola J.R., Kalkhoven, Eric, Berger, Ruud, Lips, Cornelis J.M., Medema, Rene H., Höppener, Jo W.M., Acton, Dennis S.

“…In multiple endocrine neoplasia syndrome Type 2 (MEN2), medullary thyroid carcinoma (MTC) and pheochromocytoma (PC) are associated with hereditary activating…”
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role of the disulfide bond in the interaction of islet amyloid polypeptide with membranes by Khemtémourian, Lucie, Engel, Maarten F. M, Kruijtzer, John A. W, Höppener, Jo W. M, Liskamp, Rob M. J, Killian, J. Antoinette

“…Human islet amyloid polypeptide (hIAPP) forms amyloid fibrils in pancreatic islets of patients with type 2 diabetes mellitus. It has been suggested that the…”
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Ethics: Genetic testing for MEN1--whose responsibility? by Lips, Cornelis J M, Höppener, Jo W M

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Menin links estrogen receptor activation to histone H3K4 trimethylation by DREIJERINK, Koen M. A, MULDER, Klaas W, WINKLER, G. Sebastiaan, HÖPPENER, Jo W. M, LIPS, Cornelis J. M, MARC TIMMERS, H. Th

“…The product of the multiple endocrine neoplasia type 1 (MEN1) tumor suppressor gene, menin, is an integral component of MLL1/MLL2 histone methyltransferase…”
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Medullary thyroid carcinoma: role of genetic testing and calcitonin measurement by Lips, C J, Höppener, J W, Thijssen, J H

“…All patients with a thyroid nodule should have their plasma CT measured. Stimulated CT is generally better than basal, but in the lower ranges false negatives…”
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A Novel RET Kinase-β-Catenin Signaling Pathway Contributes to Tumorigenesis in Thyroid Carcinoma by GUJRAL, Taranjit S, VAN VEELEN, Wendy, RICHARDSON, Douglas S, MYERS, Shirley M, MEENS, Jalna A, ACTON, Dennis S, DUNACH, Mireia, ELLIOTT, Bruce E, HOPPENER, Jo W. M, MULLIGAN, Lois M

“…The RET receptor tyrosine kinase has essential roles in cell survival, differentiation, and proliferation. Oncogenic activation of RET causes the cancer…”
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Mechanisms of Disease: multiple endocrine neoplasia type 1-relation to chromatin modifications and transcription regulation by Lips, Cornelis JM, Dreijerink, Koen MA, Höppener, Jo WM, Timmers, HT Marc

“…Multiple endocrine neoplasia type 1 (MEN1) is a hereditary tumor syndrome characterized by tumors of the parathyroid glands, the pancreatic islets, the…”
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Inhibition of Amyloid Fibril Formation of Human Amylin by N-Alkylated Amino Acid and -Hydroxy Acid Residue Containing Peptides by Rijkers, Dirk T. S., Höppener, Jo W. M., Posthuma, George, Lips, Cornelis J. M., Liskamp, Rob M. J.

“…Amyloid deposits are formed as a result of uncontrolled aggregation of (poly)peptides or proteins. Today several diseases are known, for example Alzheimer's…”
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A Combinatorial Approach for the Design of Complementarity-determining Region-derived Peptidomimetics with in Vitro Anti-tumoral Activity by Timmerman, Peter, Barderas, Rodrigo, Desmet, Johan, Altschuh, Danièle, Shochat, Susana, Hollestelle, Martine J., Höppener, Jo W.M., Monasterio, Alberto, Casal, J.Ignacio, Meloen, Rob H.

“…The great success of therapeutic monoclonal antibodies has fueled research toward mimicry of their binding sites and the development of new strategies for…”
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Designing antibodies for the inhibition of gastrin activity in tumoral cell lines by Barderas, Rodrigo, Shochat, Susana, Timmerman, Peter, Hollestelle, Martine J., Martínez‐Torrecuadrada, Jorge L., Höppener, Jo W.M., Altschuh, Danièle, Meloen, Rob, Casal, José Ignacio

“…Gastrin and its derivatives are becoming important targets for immunotherapy of pancreatic, gastric and colorectal tumors. This study was conducted to design…”
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Inhibition of Amyloid Fibril Formation of Human Amylin by N-Alkylated Amino Acid and α-Hydroxy Acid Residue Containing Peptides by Rijkers, Dirk T. S., Höppener, Jo W. M., Posthuma, George, Lips, Cornelis J. M., Liskamp, Rob M. J.

“…Amyloid deposits are formed as a result of uncontrolled aggregation of (poly)peptides or proteins. Today several diseases are known, for example Alzheimer's…”
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Human IAPP is a contributor to painful diabetic peripheral neuropathy by Albariqi, Mohammed Mh, Versteeg, Sabine, Brakkee, Elisabeth M, Coert, J Henk, Elenbaas, Barend Ow, Prado, Judith, Hack, C Erik, Höppener, Jo Wm, Eijkelkamp, Niels

“…Peripheral neuropathy is a frequent complication of type 2 diabetes mellitus (T2DM). We investigated whether human islet amyloid polypeptide (hIAPP), which…”
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