Search Results - "Hönzke, Katja"
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Dual-Action Heteromultivalent Glycopolymers Stringently Block and Arrest Influenza A Virus Infection In Vitro and Ex Vivo
Published in Nano letters (14-06-2023)“…Here, we demonstrate the concerted inhibition of different influenza A virus (IAV) strains using a low-molecular-weight dual-action linear polymer. The…”
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2
Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry
Published in Nature nanotechnology (01-05-2020)“…Multivalent interactions at biological interfaces occur frequently in nature and mediate recognition and interactions in essential physiological processes such…”
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Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy
Published in iScience (19-03-2021)“…Detailed knowledge of the molecular biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral…”
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Correction: State-of-the-art analytical methods of viral infections in human lung organoids
Published in PloS one (03-11-2023)“…[This corrects the article DOI: 10.1371/journal.pone.0276115.]…”
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State-of-the-art analytical methods of viral infections in human lung organoids
Published in PloS one (20-12-2022)“…Human-based organ models can provide strong predictive value to investigate the tropism, virulence, and replication kinetics of viral pathogens. Currently,…”
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6
CLEC12A Binds to Legionella pneumophila but Has No Impact on the Host's Antibacterial Response
Published in International journal of molecular sciences (15-02-2023)“…is an intracellular pathogen that can cause severe pneumonia after the inhalation of contaminated aerosols and replication in alveolar macrophages. Several…”
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7
We need to talk-how muscle stem cells communicate
Published in Frontiers in cell and developmental biology (10-07-2024)“…Skeletal muscle is one of the tissues with the highest ability to regenerate, a finely controlled process which is critically depending on muscle stem cells…”
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Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus
Published in Scientific reports (29-11-2022)“…Influenza A virus (IAV) causes pandemics and annual epidemics of severe respiratory infections. A better understanding of the molecular regulation in tissue…”
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Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities
Published in Emerging microbes & infections (01-01-2019)“…Influenza is an acute respiratory infection causing high morbidity and mortality in annual outbreaks worldwide. Antiviral drugs are limited and pose the risk…”
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10
Human alveolar progenitors generate dual lineage bronchioalveolar organoids
Published in Communications biology (25-08-2022)“…Mechanisms of epithelial renewal in the alveolar compartment remain incompletely understood. To this end, we aimed to characterize alveolar progenitors…”
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11
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
Published in Nature communications (21-06-2021)“…Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and…”
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Introducing quality measures in an academic research consortium
Published in EMBO reports (03-08-2022)“…Lessons from implementing quality control systems in an academic research consortium to improve Good Scientific Practice and reproducibility…”
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Introducing quality measures in an academic research consortium: Lessons and recommendation from implementing an ad hoc quality management system for organ model research
Published in EMBO reports (03-08-2022)“…Graphical Abstract Lessons from implementing quality control systems in an academic research consortium to improve Good Scientific Practice and reproducibility…”
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14
CLEC12A Binds to ILegionella pneumophila/I but Has No Impact on the Host’s Antibacterial Response
Published in International journal of molecular sciences (01-02-2023)“…Legionella pneumophila is an intracellular pathogen that can cause severe pneumonia after the inhalation of contaminated aerosols and replication in alveolar…”
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15
Reversion of Pneumolysin-Induced Executioner Caspase Activation Redirects Cells to Survival
Published in The Journal of infectious diseases (04-06-2021)“…Abstract Apoptosis is an indispensable mechanism for eliminating infected cells and activation of executioner caspases is considered to be a point of no…”
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Introducing quality measures in an academic research consortium: Lessons and recommendation from implementing an ad hoc quality management system for organ model research: Lessons and recommendation from implementing an ad hoc quality management system for organ model research
Published in EMBO reports (03-08-2022)Get full text
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17
State-of-the-art analytical methods of viral infections in human lung organoids
Published in PloS one (01-01-2022)“…Human-based organ models can provide strong predictive value to investigate the tropism, virulence, and replication kinetics of viral pathogens. Currently,…”
Get full text
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