Search Results - "Hořejšı́, Václav"

Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton by Brdičková, Naděžda, Brdička, Tomáš, Anděra, Ladislav, Špička, Jiřı́, Angelisová, Pavla, Milgram, Sharon L., Hořejšı́, Václav

“…Phosphoprotein associated with GEMs (PAG), also known as Csk-binding protein (Cbp), is a broadly expressed palmitoylated transmembrane adapter protein found in…”
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Novel class of peptides disintegrating biological membranes to aid in the characterization of membrane proteins by Hořejší, Václav, Angelisová, Pavla, Pokorná, Jana, Charnavets, Tatsiana, Benada, Oldřich, Čajka, Tomáš, Brdička, Tomáš

“…Styrene-maleic acid (SMA) and similar amphiphilic copolymers are known to cut biological membranes into lipid nanoparticles/nanodiscs containing membrane…”
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The roles of membrane microdomains (rafts) in T cell activation by HOREJSI, Vaclav

“…Detergent‐resistant membrane microdomains enriched in sphingolipids, cholesterol and glycosylphosphatidylinositol‐anchored proteins play essential roles in T…”
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Btk is a positive regulator in the TREM-1/DAP12 signaling pathway by Ormsby, Tereza, Schlecker, Eva, Ferdin, Janina, Tessarz, Anja Sibylle, Angelisová, Pavla, Köprülü, Afitap Derya, Borte, Michael, Warnatz, Klaus, Schulze, Ilka, Ellmeier, Wilfried, Hořejší, Václav, Cerwenka, Adelheid

“…The triggering receptor expressed on myeloid cells 1 (TREM-1) has been implicated in the production of proinflammatory cytokines and chemokines during…”
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Transmembrane adaptor proteins: organizers of immunoreceptor signalling by Schraven, Burkhart, Ho ejší, Václav, Zhang, Weiguo

“…Signalling through multichain immunoreceptors is required for the development, activation and differentiation of haematopoietic cells. One of the most…”
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A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells by Drbal, Karel, Angelisová, Pavla, Hilgert, Ivan, Černý, Jan, Novák, Petr, Hořejšı́, Václav

“…An unusual CD18 monoclonal antibody (mAb) MEM-148 binds, in contrast to standard CD18 mAbs, specifically to peripheral blood monocytes and neutrophils…”
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The use of styrene-maleic acid copolymer (SMA) for studies on T cell membrane rafts by Angelisová, Pavla, Ballek, Ondřej, Sýkora, Jan, Benada, Oldřich, Čajka, Tomáš, Pokorná, Jana, Pinkas, Dominik, Hořejší, Václav

“…An emerging alternative to the use of detergents in biochemical studies on membrane proteins is apparently the use styrene-maleic acid (SMA) amphipathic…”
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CD antigens 2002 by Mason, David, André, Pascale, Bensussan, Armand, Buckley, Chris, Civin, Curt, Clark, Edward, de Haas, Masja, Goyert, Sanna, Hadam, Martin, Hart, Derek, Hořejšı́, Václav, Meuer, Stefan, Morrissey, James, Schwartz-Albiez, Reinhard, Shaw, Stephen, Simmons, David, Uguccioni, Mariagrazia, van der Schoot, Ellen, Vivier, Eric, Zola, Heddy

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Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL by Volná, Petra, Lebduska, Pavel, Dráberová, Lubica, Símová, Sárka, Heneberg, Petr, Boubelík, Michael, Bugajev, Viktor, Malissen, Bernard, Wilson, Bridget S, Horejsí, Václav, Malissen, Marie, Dráber, Petr

“…Engagement of the Fcepsilon receptor I (FcepsilonRI) on mast cells and basophils initiates signaling pathways leading to degranulation. Early activation events…”
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T Cell Receptor Signalling Results in Rapid Tyrosine Phosphorylation of the Linker Protein LAT Present in Detergent-Resistant Membrane Microdomains by Brdička, Tomáš, Černý, Jan, Hořejšı́, Václav

“…Stimulation of human T cell line Jurkat results in rapid tyrosine phosphorylation of a 35-38 kDa protein that is found in large and buoyant detergent-resistant…”
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The mannose 6‐phosphate/insulin‐like growth factor 2 receptor mediates plasminogen‐induced efferocytosis by Ohradanova‐Repic, Anna, Machacek, Christian, Donner, Clemens, Mühlgrabner, Vanessa, Petrovčíková, Eva, Zahradníková, Alexandra, Vičíková, Kristína, Hořejší, Václav, Stockinger, Hannes, Leksa, Vladimir

“…The plasminogen system is harnessed in a wide variety of physiological processes, such as fibrinolysis, cell migration, or efferocytosis; and accordingly, it…”
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Lipid rafts and their roles in T-cell activation by HOREJSI, Vaclav

“…Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and protein composition. They are involved in many aspects of cell…”
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Disulfide Bond-Mediated Dimerization of HLA-G on the Cell Surface by Boyson, Jonathan E., Erskine, Robert, Whitman, Mary C., Chiu, Michael, Lau, Julie M., Koopman, Louise A., Valter, Markus M., Angelisova, Pavla, Horejsi, Václav, Stromfinger, Jack L.

“…HLA-G is a nonclassical class I MHC molecule with an unknown function and with unusual characteristics that distinguish it from other class I MHC molecules…”
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A New Type of Membrane Raft-Like Microdomains and Their Possible Involvement in TCR Signaling by Otahal, Pavel, Angelisova, Pavla, Hrdinka, Matous, Brdicka, Tomas, Novak, Petr, Drbal, Karel, Horejsi, Vaclav

“…Membrane rafts and signaling molecules associated with them are thought to play important roles in immunoreceptor signaling. Rafts differ in their lipid and…”
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Non-T Cell Activation Linker (NTAL) Negatively Regulates TREM-1/DAP12-Induced Inflammatory Cytokine Production in Myeloid Cells by Tessarz, Anja S, Weiler, Sandra, Zanzinger, Kai, Angelisova, Pavla, Horejsi, Vaclav, Cerwenka, Adelheid

“…The engagement of triggering receptor expressed on myeloid cells 1 (TREM-1) on macrophages and neutrophils leads to TNF-alpha and IL-8 production and enhances…”
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LAT - an important raft-associated transmembrane adaptor protein. Delivered on 6 July 2009 at the 34th FEBS Congress in Prague, Czech Republic by Horejsí, Václav, Otáhal, Pavel, Brdicka, Tomás

“…Membrane rafts are microdomains involved in a number of biologically important processes, including immunoreceptor signalling. Among the functionally important…”
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The CD85J/Leukocyte Inhibitory Receptor-1 Distinguishes between Conformed and β2-Microglobulin-Free HLA-G Molecules by Gonen-Gross, Tsufit, Achdout, Hagit, Arnon, Tal I., Gazit, Roi, Stern, Noam, Hořejší, Václav, Goldman-Wohl, Debra, Yagel, Simcha, Mandelboim, Ofer

“…Abstract For a proper development of the placenta, maternal NK cells should not attack the fetal extravillous cytotrophoblast cells. This inhibition of…”
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Membrane rafts in immunoreceptor signaling: new doubts, new proofs? by Horejšı́, Václav

“…Immunoreceptors are believed to initiate their signaling by association with membrane rafts rich in src-family kinases and other signaling molecules. Although…”
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LAT Displacement from Lipid Rafts as a Molecular Mechanism for the Inhibition of T Cell Signaling by Polyunsaturated Fatty Acids by Zeyda, Maximilian, Staffler, Gunther, Horejsi, Vaclav, Waldhausl, Werner, Stulnig, Thomas M

“…Polyunsaturated fatty acids (PUFAs) suppress immune responses and inhibit T cell activation through largely unknown mechanisms. The displacement of signaling…”
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Incorporation of Leucocyte GPI-Anchored Proteins and Protein Tyrosine Kinases into Lipid-Rich Membrane Domains of COS-7 Cells by Cebecauer, Marek, Černý, Jan, Hořejšı́, Václav

“…Several human leucocyte surface glycoproteins and two lymphoid protein kinases were transiently expressed in monkey COS-7 fibroblastoid cells. All…”
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