Search Results - "Hołówka, Joanna"

  • Showing 1 - 14 results of 14
Refine Results
  1. 1

    Lsr2, a nucleoid-associated protein influencing mycobacterial cell cycle by Kołodziej, Marta, Trojanowski, Damian, Bury, Katarzyna, Hołówka, Joanna, Matysik, Weronika, Kąkolewska, Hanna, Feddersen, Helge, Giacomelli, Giacomo, Konieczny, Igor, Bramkamp, Marc, Zakrzewska-Czerwińska, Jolanta

    Published in Scientific reports (03-02-2021)
    “…Nucleoid-associated proteins (NAPs) are responsible for maintaining highly organized and yet dynamic chromosome structure in bacteria. The genus Mycobacterium…”
    Get full text
    Journal Article
  2. 2

    The Origin of Chromosomal Replication Is Asymmetrically Positioned on the Mycobacterial Nucleoid, and the Timing of Its Firing Depends on HupB by Hołówka, Joanna, Trojanowski, Damian, Janczak, Mateusz, Jakimowicz, Dagmara, Zakrzewska-Czerwińska, Jolanta

    Published in Journal of bacteriology (15-05-2018)
    “…The bacterial chromosome undergoes dynamic changes in response to ongoing cellular processes and adaptation to environmental conditions. Among the many…”
    Get full text
    Journal Article
  3. 3

    HupB Is a Bacterial Nucleoid-Associated Protein with an Indispensable Eukaryotic-Like Tail by Hołówka, Joanna, Trojanowski, Damian, Ginda, Katarzyna, Wojtaś, Bartosz, Gielniewski, Bartłomiej, Jakimowicz, Dagmara, Zakrzewska-Czerwińska, Jolanta

    Published in mBio (07-11-2017)
    “…In bacteria, chromosomal DNA must be efficiently compacted to fit inside the small cell compartment while remaining available for the proteins involved in…”
    Get full text
    Journal Article
  4. 4

    Mycobacterial IHF is a highly dynamic nucleoid-associated protein that assists HupB in organizing chromatin by Hołówka, Joanna, Łebkowski, Tomasz, Feddersen, Helge, Giacomelli, Giacomo, Drużka, Karolina, Makowski, Łukasz, Trojanowski, Damian, Broda, Natalia, Bramkamp, Marc, Zakrzewska-Czerwińska, Jolanta

    Published in Frontiers in microbiology (07-03-2023)
    “…Nucleoid-associated proteins (NAPs) crucially contribute to organizing bacterial chromatin and regulating gene expression. Among the most highly expressed NAPs…”
    Get full text
    Journal Article
  5. 5

    Choreography of the Mycobacterium replication machinery during the cell cycle by Trojanowski, Damian, Ginda, Katarzyna, Pióro, Monika, Hołówka, Joanna, Skut, Partycja, Jakimowicz, Dagmara, Zakrzewska-Czerwińska, Jolanta

    Published in mBio (17-02-2015)
    “…It has recently been demonstrated that bacterial chromosomes are highly organized, with specific positioning of the replication initiation region. Moreover,…”
    Get full text
    Journal Article
  6. 6

    Lsr2 and Its Novel Paralogue Mediate the Adjustment of Mycobacterium smegmatis to Unfavorable Environmental Conditions by Kołodziej, Marta, Łebkowski, Tomasz, Płociński, Przemysław, Hołówka, Joanna, Paściak, Mariola, Wojtaś, Bartosz, Bury, Katarzyna, Konieczny, Igor, Dziadek, Jarosław, Zakrzewska-Czerwińska, Jolanta

    Published in mSphere (12-05-2021)
    “…Lsr2 is a nucleoid-associated protein (NAP) that has been found strictly in actinobacteria, including mycobacteria. It is a functional homolog of histone-like…”
    Get full text
    Journal Article
  7. 7

    Nucleoid Associated Proteins: The Small Organizers That Help to Cope With Stress by Hołówka, Joanna, Zakrzewska-Czerwińska, Jolanta

    Published in Frontiers in microbiology (08-04-2020)
    “…The bacterial chromosome must be efficiently compacted to fit inside the small and crowded cell while remaining accessible for the protein complexes involved…”
    Get full text
    Journal Article
  8. 8

    MksB is a novel mycobacterial condensin that orchestrates spatiotemporal positioning of replication machinery by Bułacz, Hanna, Hołówka, Joanna, Wójcik, Wiktoria, Zakrzewska-Czerwińska, Jolanta

    Published in Scientific reports (16-08-2024)
    “…Condensins play important roles in maintaining bacterial chromatin integrity. In mycobacteria, three types of condensins have been characterized: a homolog of…”
    Get full text
    Journal Article
  9. 9

    Watching DNA Replication Inhibitors in Action: Exploiting Time-Lapse Microfluidic Microscopy as a Tool for Target-Drug Interaction Studies in Mycobacterium by Trojanowski, Damian, Kołodziej, Marta, Hołówka, Joanna, Müller, Rolf, Zakrzewska-Czerwińska, Jolanta

    Published in Antimicrobial agents and chemotherapy (01-10-2019)
    “…Spreading resistance to antibiotics and the emergence of multidrug-resistant strains have become frequent in many bacterial species, including mycobacteria,…”
    Get full text
    Journal Article
  10. 10

    Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective by Trojanowski, Damian, Hołówka, Joanna, Zakrzewska-Czerwińska, Jolanta

    Published in Frontiers in microbiology (26-11-2018)
    “…Bacterial chromosomes have a single, unique replication origin (named ), from which DNA synthesis starts. This study describes methods of visualizing regions…”
    Get full text
    Journal Article
  11. 11

    Multifork chromosome replication in slow-growing bacteria by Trojanowski, Damian, Hołówka, Joanna, Ginda, Katarzyna, Jakimowicz, Dagmara, Zakrzewska-Czerwińska, Jolanta

    Published in Scientific reports (06-03-2017)
    “…The growth rates of bacteria must be coordinated with major cell cycle events, including chromosome replication. When the doubling time (Td) is shorter than…”
    Get full text
    Journal Article
  12. 12

    Structure of bacterial chromosome: An analysis of DNA-protein interactions in vivo by Hołówka, Joanna, Płachetka, Małgorzata

    “…According to recent reports, bacterial chromosomes exhibit a hierarchical organization. The number of proteins that bind DNA are responsible for local and…”
    Get full text
    Journal Article
  13. 13

    Searching for new antibiotics--inhibitors of bacterial chromosome replication by Trojanowski, Damian, Skut, Patrycja, Hołówka, Joanna, Szafran, Marcin Jan

    “…The excessive and often unreasonable use of antibacterial drugs leads to rise of antibioticresistant strains. To overcome this problem, new antibiotics are…”
    Get full text
    Journal Article
  14. 14