Search Results - "Ho, Wai Lok"
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A Gold@Polydopamine Core–Shell Nanoprobe for Long-Term Intracellular Detection of MicroRNAs in Differentiating Stem Cells
Published in Journal of the American Chemical Society (17-06-2015)“…The capability of monitoring the differentiation process in living stem cells is crucial to the understanding of stem cell biology and the practical…”
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2
Slot-Waveguide Based All-Optical RF Spectrum Analyzer
Published in Photonics (01-12-2023)“…All-optical radio-frequency spectrum analyzers (AORFSAs) with ultrabroad bandwidth break the electronic bottleneck and provide an efficient frequency analysis…”
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Integrating temporal and spatial control of electronic transitions for bright multiphoton upconversion
Published in Nature communications (18-04-2019)“…The applications of lanthanide-doped upconversion nanomaterials are limited by unsatisfactory brightness currently. Herein, a general strategy is proposed for…”
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How Do Cells Exocytose Nanoparticles?
Published in Biochemistry (Easton) (01-08-2023)Get full text
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Sub-10 nm Substrate Roughness Promotes the Cellular Uptake of Nanoparticles by Upregulating Endocytosis-Related Genes
Published in Nano letters (24-02-2021)“…Nanosubstrate engineering is an established approach for modulating cellular responses, but it remains infrequently exploited to facilitate the intracellular…”
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Nano–Cell Interactions of Non-Cationic Bionanomaterials
Published in Accounts of chemical research (18-06-2019)“…Conspectus Advances in nanotechnology have empowered the design of bionanomaterials by assembling different types of natural biomolecules (e.g., nucleic acids,…”
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Effect of Alkylation on the Cellular Uptake of Polyethylene Glycol-Coated Gold Nanoparticles
Published in ACS nano (27-06-2017)“…Alkyl groups (C n H2n+1) are prevalent in engineered bionanomaterials used for many intracellular applications, yet how alkyl groups dictate the interactions…”
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Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells
Published in Journal of advanced research (01-07-2022)“…[Display omitted] The regenerative capacity of mesenchymal stromal cells or medicinal signaling cells (MSCs) is largely mediated by their secreted small…”
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Effect of Surface Modification with Hydrocarbyl Groups on the Exocytosis of Nanoparticles
Published in Biochemistry (Easton) (06-04-2021)“…Designing nanoparticles (NPs) with desirable cell type-specific exocytosis properties, say promoting their exocytosis from scavenging cell types (e.g.,…”
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A pH-Reversible Fluorescent Probe for in Situ Imaging of Extracellular Vesicles and Their Secretion from Living Cells
Published in Nano letters (10-11-2021)“…Our knowledge in how extracellular vesicles (EVs) are secreted from cells remains inadequate due to the limited technologies available for visualizing them in…”
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Alkyl-Terminated Gold Nanoparticles as a Self-Therapeutic Treatment for Psoriasis
Published in Nano letters (27-10-2021)“…We present a self-therapeutic nanoparticle for topical delivery to epidermal keratinocytes to prevent and treat psoriasis. Devoid of known chemical or…”
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Mammalian Cells Exocytose Alkylated Gold Nanoparticles via Extracellular Vesicles
Published in ACS nano (22-02-2022)“…Understanding the exocytosis of nanoparticles (NPs) from cells is valuable because it informs design rules of NPs that support desirable cellular retention for…”
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Morphological Diversity, Protein Adsorption, and Cellular Uptake of Polydopamine-Coated Gold Nanoparticles
Published in Langmuir (20-11-2018)“…Polydopamine (PDA)-coated nanoparticles are adhesive bionanomaterials widely utilized in intracellular applications, yet how their adhesiveness affects their…”
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Toward Understanding in Vivo Sequestration of Nanoparticles at the Molecular Level
Published in ACS nano (27-03-2018)“…A longstanding and widely accepted bottleneck in the targeted delivery of intravenously injected nanoparticles lies in their clearance by macrophages in the…”
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Intrapulmonary Cellular-Level Distribution of Inhaled Nanoparticles with Defined Functional Groups and Its Correlations with Protein Corona and Inflammatory Response
Published in ACS nano (24-12-2019)“…Concerns over the health risks associated with airborne exposure to ultrafine particles [PM0.1, or nanoparticles (NPs)] call for a comprehensive understanding…”
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Intranuclear Delivery of DNA Nanostructures via Cellular Mechanotransduction
Published in Nano letters (27-04-2022)“…DNA nanostructures are attractive gene carriers for nanomedicine applications, yet their delivery to the nucleus remains inefficient. We present the…”
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Third-harmonic generation in CMOS-compatible highly doped silica micro-ring resonator
Published in Optics express (06-01-2020)“…We present the first demonstration of visible emission from highly doped silica glass micro-ring resonators (MRRs) through a third-harmonic generation (THG)…”
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Specific Delivery of Oligonucleotides to the Cell Nucleus via Gentle Compression and Attachment of Polythymidine
Published in ACS applied materials & interfaces (07-08-2019)“…Nonviral delivery of nucleic acids to the cell nucleus typically requires chemical methods that do not guarantee specific delivery (e.g., transfection agent)…”
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Oligonucleotide-conjugated nanoparticles for targeted drug delivery via scavenger receptors class A: An in vitro assessment for proof-of-concept
Published in International journal of pharmaceutics (30-10-2017)“…[Display omitted] Spherical nucleic acid gold nanoparticles represent a unique nanotechnology in which the spherical arrangement of oligonucleotides enables…”
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