Search Results - "Ho, W M"

Considerations when prescribing trimethoprim-sulfamethoxazole by Ho, Joanne M-W, Juurlink, David N

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Drug interactions with cannabinoids by Antoniou, Tony, Bodkin, Jack, Ho, Joanne M-W

“…Antoniou et al present several facts about drug interactions with cannabinoids. Among other things, cannabinoids can affect levels of other drugs. Cannabidiol…”
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Global incidence of prostate cancer in developing and developed countries with changing age structures by Teoh, Jeremy Y C, Hirai, Hoyee W, Ho, Jason M W, Chan, Felix C H, Tsoi, Kelvin K F, Ng, Chi Fai

“…To investigate the global incidence of prostate cancer with special attention to the changing age structures. Data regarding the cancer incidence and…”
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Barriers and facilitators for optimizing oral anticoagulant management: Perspectives of patients, caregivers, and providers by Holbrook, Anne, Wang, Mei, Swinton, Marilyn, Troyan, Sue, Ho, Joanne M. W, Siegal, Deborah M

“…Background Oral anticoagulants (OACs) are very commonly prescribed for prevention of serious vascular events, but are also associated with serious…”
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Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators by Hart, Kathryn M, Moeder, Katelyn E, Ho, Chris M W, Zimmerman, Maxwell I, Frederick, Thomas E, Bowman, Gregory R

“…Allosteric drugs, which bind to proteins in regions other than their main ligand-binding or active sites, make it possible to target proteins considered…”
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Efficiency and effectiveness of geriatric drug infographics: A randomized, controlled trial by Tung, Jennifer, Bodkin, R. Jack, Laughton, Thomas, Neat, Cameron, Benjamin, Sophiya, An, Howard, Antoniou, Tony, Ho, Joanne M.‐W.

“…Adverse drug events (ADEs) are a leading cause of mortality, disability, and healthcare costs in older adults due to multimorbidity, age-related changes to…”
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EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis by Tonna, Stephen, Takyar, Farzin M., Vrahnas, Christina, Crimeen‐Irwin, Blessing, Ho, Patricia W. M., Poulton, Ingrid J., Brennan, Holly J., McGregor, Narelle E., Allan, Elizabeth H., Nguyen, Huynh, Forwood, Mark R., Tatarczuch, Liliana, Mackie, Eleanor J., Martin, T. John, Sims, Natalie A.

“…Cells that form bone (osteoblasts) express both ephrinB2 and EphB4, and previous work has shown that pharmacological inhibition of the eph‐rinB2/EphB4…”
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A mechanism for lipid binding to apoE and the role of intrinsically disordered regions coupled to domain–domain interactions by Frieden, Carl, Wang, Hanliu, Ho, Chris M. W.

“…Relative to the apolipoprotein E (apoE) E3 allele of the APOE gene, apoE4 strongly increases the risk for the development of late-onset Alzheimer’s disease…”
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EphrinB2/EphB4 inhibition in the osteoblast lineage modifies the anabolic response to parathyroid hormone by Takyar, Farzin M, Tonna, Stephen, Ho, Patricia WM, Crimeen‐Irwin, Blessing, Baker, Emma K, Martin, T John, Sims, Natalie A

“…Previous reports indicate that ephrinB2 expression by osteoblasts is stimulated by parathyroid hormone (PTH) and its related protein (PTHrP) and that…”
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Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo by Ho, P W M, Goradia, A, Russell, M R, Chalk, A M, Milley, K M, Baker, E K, Danks, J A, Slavin, J L, Walia, M, Crimeen-Irwin, B, Dickins, R A, Martin, T J, Walkley, C R

“…Osteosarcoma (OS) is the most common cancer of bone. Parathyroid hormone (PTH) regulates calcium homeostasis and bone development, while the…”
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Adults with autism are less proficient in identifying biological motion actions portrayed with point‐light displays by Hsiung, E.‐Y., Chien, S. H.‐L., Chu, Y.‐H., Ho, M. W.‐R.

“…Background Whether individuals with autism spectrum disorder (ASD) have impairments with biological motion perception has been debated. The present study…”
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Comprehensive analysis of risk factors associating with Hepatitis B virus (HBV) reactivation in cancer patients undergoing cytotoxic chemotherapy by YEO, W, ZEE, B, ZHONG, S, CHAN, P. K. S, WONG, W-L, HO, W. M, LAM, K. C, JOHNSON, P. J

“…For cancer patients with chronic hepatitis B virus (HBV) infection, who receive cytotoxic chemotherapy, HBV reactivation is a well-described complication,…”
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Modelling proteins’ hidden conformations to predict antibiotic resistance by Hart, Kathryn M., Ho, Chris M. W., Dutta, Supratik, Gross, Michael L., Bowman, Gregory R.

“…TEM β-lactamase confers bacteria with resistance to many antibiotics and rapidly evolves activity against new drugs. However, functional changes are not easily…”
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Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin by Whitworth, Alexander J, Lee, Jeffrey R, Ho, Venus M-W, Flick, Robert, Chowdhury, Ruhena, McQuibban, G Angus

“…Parkinson's disease (PD) is a common neurodegenerative disorder caused by loss of midbrain dopaminergic neurons, the pathogenetic mechanisms of which remain…”
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A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride by Antoniou, Tony, Macdonald, Erin M, Yao, Zhan, Gomes, Tara, Tadrous, Mina, Ho, Joanne M-W, Mamdani, Muhammad M, Juurlink, David N

“…Dutasteride is a potent inhibitor of 5-alpha reductase enzymes that reduces concentrations of dihydrotestosterone to a greater extent than finasteride. Whether…”
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Risk of serious falls associated with oxybutynin and tolterodine: a population based study by Gomes, Tara, Juurlink, David N, Ho, Joanne M-W, Schneeweiss, Sebastian, Mamdani, Muhammad M

“…We compared the short-term risk of falls among recipients of oxybutynin or tolterodine to treat urinary incontinence. We conducted a population based,…”
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Sustained RANKL response to parathyroid hormone in oncostatin M receptor-deficient osteoblasts converts anabolic treatment to a catabolic effect in vivo by Walker, Emma C, Poulton, Ingrid J, McGregor, Narelle E, Ho, Patricia WM, Allan, Elizabeth H, Quach, Julie M, Martin, T John, Sims, Natalie A

“…Parathyroid hormone (PTH) is the only approved anabolic agent for osteoporosis treatment. It acts via osteoblasts to stimulate both osteoclast formation and…”
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Liver resection for hepatocellular carcinoma in patients with cirrhosis by Wu, C.-C., Cheng, S.-B., Ho, W.-M., Chen, the late J.-T., Liu, T.-J., P'eng, F.-K.

“…Background: Although liver resection is now a safe procedure, its role for hepatocellular carcinoma (HCC) in patients with cirrhosis remains controversial…”
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Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction by Ramsden, David B., Ho, Philip W.‐L., Ho, Jessica W.‐M., Liu, Hui‐Fang, So, Danny H.‐F., Tse, Ho‐Man, Chan, Koon‐Ho, Ho, Shu‐Leong

“…Uncoupling proteins (UCPs) belong to a large family of mitochondrial solute carriers 25 (SLC25s) localized at the inner mitochondrial membrane. UCPs transport…”
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Total Neoadjuvant Therapy for High Risk Rectal Cancer in Western and Asian Populations – Current Evidence and Clinical Applications by Johnson, David, Li, Leung, Lee, Kin-Chung, Lam, KO, Wong, KH, Ho, WM, Ma, Brigette

“…Recent data from several randomized controlled trials (RCTs) have shown that Total Neoadjuvant Therapy (TNT) can improve the treatment outcome of patients with…”
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