Search Results - "Ho, Vincent T."

Donor Clonal Hematopoiesis and Recipient Outcomes After Transplantation by Gibson, Christopher J, Kim, Haesook T, Zhao, Lin, Murdock, H Moses, Hambley, Bryan, Ogata, Alana, Madero-Marroquin, Rafael, Wang, Shiyu, Green, Lisa, Fleharty, Mark, Dougan, Tyler, Cheng, Chi-An, Blumenstiel, Brendan, Cibulskis, Carrie, Tsuji, Junko, Duran, Madeleine, Gocke, Christopher D, Antin, Joseph H, Nikiforow, Sarah, DeZern, Amy E, Chen, Yi-Bin, Ho, Vincent T, Jones, Richard J, Lennon, Niall J, Walt, David R, Ritz, Jerome, Soiffer, Robert J, Gondek, Lukasz P, Lindsley, R Coleman

“…Clonal hematopoiesis (CH) can be transmitted from a donor to a recipient during allogeneic hematopoietic cell transplantation. Exclusion of candidate donors…”
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Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease by Koreth, John, Kim, Haesook T., Jones, Kyle T., Lange, Paulina B., Reynolds, Carol G., Chammas, Marie J., Dusenbury, Katherine, Whangbo, Jennifer, Nikiforow, Sarah, Alyea, Edwin P., Armand, Philippe, Cutler, Corey S., Ho, Vincent T., Chen, Yi-Bin, Avigan, David, Blazar, Bruce R., Antin, Joseph H., Ritz, Jerome, Soiffer, Robert J.

“…Chronic graft-versus-host disease (cGVHD) is associated with inadequate reconstitution of tolerogenic CD4+CD25+FOXP3+ regulatory T cells (Tregs). Previous…”
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ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death by Vander Lugt, Mark T, Braun, Thomas M, Hanash, Samir, Ritz, Jerome, Ho, Vincent T, Antin, Joseph H, Zhang, Qing, Wong, Chee-Hong, Wang, Hong, Chin, Alice, Gomez, Aurélie, Harris, Andrew C, Levine, John E, Choi, Sung W, Couriel, Daniel, Reddy, Pavan, Ferrara, James L.M, Paczesny, Sophie

“…Serum levels of an interleukin-1 receptor family member called suppressor of tumorigenicity 2 (ST2) predict response to therapy for graft-versus-host disease…”
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A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation by Davids, Matthew S., Kim, Haesook T., Costello, Caitlin, Herrera, Alex F., Locke, Frederick L., Maegawa, Rodrigo O., Savell, Alexandra, Mazzeo, Michael, Anderson, Adrienne, Boardman, Alexander P., Weber, Augustine, Avigan, David, Chen, Yi-Bin, Nikiforow, Sarah, Ho, Vincent T., Cutler, Corey, Alyea, Edwin P., Bachireddy, Pavan, Wu, Catherine J., Ritz, Jerome, Streicher, Howard, Ball, Edward D., Bashey, Asad, Soiffer, Robert J., Armand, Philippe

“…Programmed cell death-1 (PD-1)/programmed death ligand-1 blockade may potentially augment graft-vs-tumor effects following allogeneic hematopoietic cell…”
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Innovations in conditioning and post-transplant maintenance in AML: genomically informed revelations on the graft-versus-leukemia effect by Murdock, H Moses, Ho, Vincent T, Garcia, Jacqueline S

“…Acute Myeloid Leukemia (AML) is the prototype of cancer genomics as it was the first published cancer genome. Large-scale next generation/massively parallel…”
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Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation by Cutler, Corey, Multani, Pratik, Robbins, David, Kim, Haesook T., Le, Thuy, Hoggatt, Jonathan, Pelus, Louis M., Desponts, Caroline, Chen, Yi-Bin, Rezner, Betsy, Armand, Philippe, Koreth, John, Glotzbecker, Brett, Ho, Vincent T., Alyea, Edwin, Isom, Marlisa, Kao, Grace, Armant, Myriam, Silberstein, Leslie, Hu, Peirong, Soiffer, Robert J., Scadden, David T., Ritz, Jerome, Goessling, Wolfram, North, Trista E., Mendlein, John, Ballen, Karen, Zon, Leonard I., Antin, Joseph H., Shoemaker, Daniel D.

“…Umbilical cord blood (UCB) is a valuable source of hematopoietic stem cells (HSCs) for use in allogeneic transplantation. Key advantages of UCB are rapid…”
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A prognostic score for acute graft-versus-host disease based on biomarkers: a multicentre study by Levine, John E, Prof, Braun, Thomas M, Prof, Harris, Andrew C, MD, Holler, Ernst, MD, Taylor, Austin, BA, Miller, Holly, DO, Magenau, John, MD, Weisdorf, Daniel J, Prof, Ho, Vincent T, MD, Bolaños-Meade, Javier, MD, Alousi, Amin M, MD, Ferrara, James L M, Prof

“…Summary Background Graft-versus-host disease (GVHD) is the major cause of non-relapse mortality after allogeneic haemopoietic stem-cell transplantation (SCT)…”
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Gene expression–based discovery of atovaquone as a STAT3 inhibitor and anticancer agent by Xiang, Michael, Kim, Haesook, Ho, Vincent T., Walker, Sarah R., Bar-Natan, Michal, Anahtar, Melodi, Liu, Suhu, Toniolo, Patricia A., Kroll, Yasmin, Jones, Nichole, Giaccone, Zachary T., Heppler, Lisa N., Ye, Darwin Q., Marineau, Jason J., Shaw, Daniel, Bradner, James E., Blonquist, Traci, Neuberg, Donna, Hetz, Claudio, Stone, Richard M., Soiffer, Robert J., Frank, David A.

“…The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is frequently activated inappropriately in a wide range of…”
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Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation by Armand, Philippe, Kim, Haesook T., Cutler, Corey S., Ho, Vincent T., Koreth, John, Alyea, Edwin P., Soiffer, Robert J., Antin, Joseph H.

“…Iron overload could be a significant contributor to treatment-related mortality (TRM) for patients with hematologic malignancies undergoing hematopoietic stem…”
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Acute GVHD Diagnosis and Adjudication in a Multicenter Trial: A Report From the BMT CTN 1202 Biorepository Study by Reshef, Ran, Saber, Wael, Bolaños-Meade, Javier, Chen, George, Chen, Yi-Bin, Ho, Vincent T, Ponce, Doris M, Nakamura, Ryotaro, Martens, Michael J, Hansen, John A, Levine, John E

“…Accurate and reproducible methods to diagnose, grade, and report acute graft-versus-host disease (GVHD) are critical for the evaluation of therapies and…”
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Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation by Penter, Livius, Zhang, Yi, Savell, Alexandra, Huang, Teddy, Cieri, Nicoletta, Thrash, Emily M., Kim-Schulze, Seunghee, Jhaveri, Aashna, Fu, Jingxin, Ranasinghe, Srinika, Li, Shuqiang, Zhang, Wandi, Hathaway, Emma S., Nazzaro, Matthew, Kim, Haesook T., Chen, Helen, Thurin, Magdalena, Rodig, Scott J., Severgnini, Mariano, Cibulskis, Carrie, Gabriel, Stacey, Livak, Kenneth J., Cutler, Corey, Antin, Joseph H., Nikiforow, Sarah, Koreth, John, Ho, Vincent T., Armand, Philippe, Ritz, Jerome, Streicher, Howard, Neuberg, Donna, Hodi, F. Stephen, Gnjatic, Sacha, Soiffer, Robert J., Liu, X. Shirley, Davids, Matthew S., Bachireddy, Pavan, Wu, Catherine J.

“…Relapsed myeloid disease after allogeneic stem cell transplantation (HSCT) remains largely incurable. We previously demonstrated the potent activity of immune…”
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Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease by Sarantopoulos, Stefanie, Stevenson, Kristen E., Kim, Haesook T., Cutler, Corey S., Bhuiya, Nazmim S., Schowalter, Michael, Ho, Vincent T., Alyea, Edwin P., Koreth, John, Blazar, Bruce R., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome

“…Chronic graft-versus-host disease (cGVHD) causes significant morbidity and mortality in patients otherwise cured of malignancy after hematopoietic stem cell…”
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Prospective cohort study comparing intravenous busulfan to total body irradiation in hematopoietic cell transplantation by Bredeson, Christopher, LeRademacher, Jennifer, Kato, Kazunobu, DiPersio, John F., Agura, Edward, Devine, Steven M., Appelbaum, Frederick R., Tomblyn, Marcie R., Laport, Ginna G., Zhu, Xiaochun, McCarthy, Philip L., Ho, Vincent T., Cooke, Kenneth R., Armstrong, Elizabeth, Smith, Angela, Rizzo, J. Douglas, Burkart, Jeanne M., Pasquini, Marcelo C.

“…We conducted a prospective cohort study testing the noninferiority of survival of ablative intravenous busulfan (IV-BU) vs ablative total body irradiation…”
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Allogeneic hematopoietic cell transplantation outcomes in patients with Richter's transformation by Kim, Haesook T, Baker, Peter O, Parry, Erin, Davids, Matthew, Alyea, Edwin P, Ho, Vincent T, Cutler, Corey, Koreth, John, Gooptu, Mahasweta, Romee, Rizwan, Nikiforow, Sarah, Antin, Joseph H, Ritz, Jerome, Soiffer, Robert J, Wu, Catherine J, Brown, Jennifer R

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Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial by Cutler, Corey, Kim, Haesook T., Bindra, Bhavjot, Sarantopoulos, Stefanie, Ho, Vincent T., Chen, Yi-Bin, Rosenblatt, Jacalyn, McDonough, Sean, Watanaboonyongcharoen, Phandee, Armand, Philippe, Koreth, John, Glotzbecker, Brett, Alyea, Edwin, Blazar, Bruce R., Soiffer, Robert J., Ritz, Jerome, Antin, Joseph H.

“…B cells are implicated in the pathophysiology of chronic graft-vs-host disease (GVHD), and phase 2 trials suggest that B cell depletion can treat established…”
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Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant by Cheng, Guang-Shing, Storer, Barry, Chien, Jason W, Jagasia, Madan, Hubbard, Jesse J, Burns, Linda, Ho, Vincent T, Pidala, Joseph, Palmer, Jeanne, Johnston, Laura, Mayer, Sebastian, Crothers, Kristina, Pusic, Iskra, Lee, Stephanie J, Williams, Kirsten M

“…The natural history of lung function in patients with bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic cell transplant is poorly…”
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Risk of Latent Tuberculosis Reactivation After Hematopoietic cell Transplantation by Cheng, Matthew P, Kusztos, Amanda E, Bold, Tyler D, Ho, Vincent T, Glotzbecker, Brett E, Hsieh, Candace, Baker, Meghan A, Baden, Lindsey R, Hammond, Sarah P, Marty, Francisco M

“…Abstract There were no cases of tuberculosis in a cohort of 2531 patients who underwent hematopoietic cell transplantation from 2010 to 2015 after 7323…”
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Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy by Gavriilaki, Eleni, Ho, Vincent T, Schwaeble, Wilhelm, Dudler, Thomas, Daha, Mohamed, Fujita, Teizo, Jodele, Sonata

“…Hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) is a life-threatening syndrome that occurs in adult and pediatric…”
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Phenotypic and functional characterization of the CD6-ALCAM T-cell co-stimulatory pathway after allogeneic cell transplantation by Rambaldi, Benedetta, Kim, Haesook T., Arihara, Yohei, Asano, Takeru, Reynolds, Carol, Manter, Mariah, Halpern, Max, Weber, Augustine, Koreth, John, Cutler, Corey, Gooptu, Mahasweta, Nikiforow, Sarah, Ho, Vincent T., Antin, Joseph H., Romee, Rizwan, Ampudia, Jeanette, Ng, Cherie, Connelly, Stephen, Soiffer, Robert J., Ritz, Jerome

“…CD6 is a co-stimulatory receptor expressed on T cells that binds activated leukocyte cell adhesion molecule (ALCAM), expressed on antigen presenting cells,…”
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Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network by Alousi, Amin M., Weisdorf, Daniel J., Logan, Brent R., Bolaños-Meade, Javier, Carter, Shelly, DiFronzo, Nancy, Pasquini, Marcelo, Goldstein, Steven C., Ho, Vincent T., Hayes-Lattin, Brandon, Wingard, John R., Horowitz, Mary M., Levine, John E.

“…Acute graft-versus-host disease (aGVHD) is the primary limitation of allogeneic hematopoietic cell transplantation. Corticosteroids remain the standard initial…”
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