Search Results - "Ho, R L"

HBx mutants differentially affect the activation of hypoxia-inducible factor-1α in hepatocellular carcinoma by Liu, L-p, Hu, B-g, Ye, C, Ho, R L K, Chen, G G, Lai, P B S

“…Background: Mutations in HBx gene are frequently found in HBV-associated hepatocellular carcinoma (HCC). Activation of hypoxia-inducible factor-1 α (HIF-1 α )…”
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Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma by Cheng, Y, Ho, R L K Y, Chan, K C, Kan, R, Tung, E, Lung, H L, Yau, W L, Cheung, A K L, Ko, J M Y, Zhang, Z F, Luo, D Z, Feng, Z B, Chen, S, Guan, X Y, Kwong, D, Stanbridge, E J, Lung, M L

“…Zinc-finger, MYND-type containing 10 ( ZMYND10 ), or more commonly called BLU, expression is frequently downregulated in nasopharyngeal carcinoma (NPC) and…”
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Systems Biology: An Evolving Approach in Drug Discovery and Development by Ho, R. L., Lieu, C. A.

“…Investments in systems biology approaches by the pharmaceutical industry have not yet yielded the payoffs envisaged by many. In most cases, a plethora of novel…”
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Single nucleotide polymorphism in the promoter region of human alpha-fetoprotein (AFP) gene and its significance in hepatocellular carcinoma (HCC) by Chen, G.G, Ho, R.L.K, Wong, J, Lee, K.F, Lai, P.B.S

“…Abstract Background Variations of serum AFP levels in HCC patients and cell lines are likely due to the differential activity of enhancer/silencer elements…”
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Systemic cytokine response after laparoscopic-assisted resection of rectosigmoid carcinoma : A prospective randomized trial by KA LAU LEUNG, LAI, P. B. S, HO, R. L. K, MENG, W. C. S, YIU, R. Y. C, LEE, J. F. Y, WAN YEE LAU

“…To compare the systemic cytokine response in patients after laparoscopic-assisted resection with those after open resection of rectosigmoid carcinoma…”
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Identification of hepatitis B virus X gene mutation in Hong Kong patients with hepatocellular carcinoma by Chen, G.G., Li, M.Y., Ho, R.L.K., Chak, E.C.W., Lau, W.Y., Lai, P.B.S.

“…Chronic infection by hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) in man. The viral transactivator HBV X (HBx) gene plays a…”
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Decreased expression of Bid in human hepatocellular carcinoma is related to hepatitis B virus X protein by Chen, G.G., Lai, P.B.S., Chan, P.K.S., Chak, E.C.W., Yip, J.H.Y., Ho, R.L.K., Leung, B.C.S., Lau, W.Y.

“…As a mitochondrial membrane death ligand, Bid oligomerises Bak to release cytochrome C and its deficiency renders hepatocytes resistant to apoptosis induced by…”
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PROSPECTIVE RANDOMIZED CONTROL STUDY ON THE EFFECT OF BRANCHED-CHAIN AMINO ACIDS IN PATIENTS WITH LIVER RESECTION FOR HEPATOCELLULAR CARCINOMA by Meng, W. C. S., Leung, K. L., Ho, R. L. K., Leung, T. W. T., Lau, W. Y.

“…Background: Aminoleban EN contains branched‐chain amino acids (BCAA) and is known to be beneficial for the protein‐energy malnutrition in cirrhotic patients…”
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HBx mutants differentially affect the activation of hypoxia-inducible factor-1[alpha] in hepatocellular carcinoma by Liu, L-p, Hu, B-g, Ye, C, Ho, R L K, Chen, G G, Lai, P B S

“…Mutations in HBx gene are frequently found in HBV-associated hepatocellular carcinoma (HCC). Activation of hypoxia-inducible factor-1α (HIF-1α) contributes to…”
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Adriamycin-induced modulation of host defenses in tumor-bearing mice by MACCUBBIN, D. L, WING, K. R, MACE, K. F, HO, R. L. X, EHRKE, M. J, MIHICH, E

“…Using the C57BL/6/EL4 tumor model, studies were carried out to demonstrate the feasibility of administering Adriamycin (ADM) in therapeutic doses and schedules…”
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Specific anti-EL4-lymphoma immunity in mice cured 2 years earlier with doxorubicin and interleukin-2 by EHRKE, M. J, VERSTOVSEK, S, ZALESKIS, G, HO, R. L. X, UJHAZY, P, MACCUBBIN, D. L, MIHICH, E

“…This laboratory has reported the conditions for an effective, non-toxic, chemoimmunotherapy utilizing doxorubicin in combination with prolonged administration…”
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Development of a safe and effective adriamycin plus interleukin 2 therapy against both adriamycin-sensitive and -resistant lymphomas by Ho, R L, Maccubbin, D, Zaleskis, G, Krawczyk, C, Wing, K, Mihich, E, Ehrke, M J

“…This laboratory has extensively studied Adriamycin (doxorubicin)-induced immunomodulation. Despite demonstration of favorable effects, little therapeutic…”
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Species-specific TNF induction of thymocyte proliferation by EHRKE, M. J, HO, R. L. X, HORI, K

“…Recombinant murine (rMu) tumor necrosis factor (TNF), in a standard comitogenic assay with phytohemagglutinin, induced murine thymocyte proliferation, while up…”
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Intracellular doxorubicin kinetics in lymphoma cells and lymphocytes infiltrating the tumor area in vivo: a flow cytometric study by Zaleskis, G, Ho, R L, Diegelman, P, Maccubbin, D, Ujházy, P, Mihich, E, Ehrke, M J

“…Recently we have reported the development of a safe and effective chemoimmunotherapy protocol involving doxorubicin (Dox) in combination with interleukin 2…”
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Immunological responses critical to the therapeutic effects of adriamycin plus interleukin 2 in C57BL/6 mice bearing syngeneic EL4 lymphoma by Ho, R L, Maccubbin, D L, Ujházy, P, Zaleskis, G, Eppolito, C, Mihich, E, Ehrke, M J

“…A safe and effective therapeutic combination of moderate doses of Adriamycin (doxorubicin, 4 mg/kg, IV, Days 1 and 8 or only Day 8) plus prolonged…”
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Pentaglobin in steroid-resistant severe acute respiratory syndrome by HO, J. C, WU, A. Y, TSANG, K. W, LAM, B, OOI, G. C, KHONG, P-L, HO, P. L, CHAN-YEUNG, M, ZHONG, N-S, KO, C, LAM, W. K

“…SETTING: The treatment of severe acute respiratory syndrome (SARS) is at best controversial, although there is considerable anecdotal experience to show the…”
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Effects of a Care Protocol on Care Outcomes in Older Nursing Home Patients with Chronic Obstructive Pulmonary Disease by Lee, Diana T. F., Lee, Iris F. K., Mackenzie, Ann E., Ho, Rosalie N. L.

“…OBJECTIVES: To evaluate the effects of a care protocol used by community nurses to support nursing home staff in the care of patients with chronic obstructive…”
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An audio watermarking algorithm based on significant component modulation by Yi-Lun Ho, Hsiao-Chuan Wang

“…Digital watermarking which hides the binary information in the digital multimedia files is an effective method for copyright protection. We propose a new…”
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The relationship between multidrug resistance and tumor necrosis factor resistance in an EL4 cell line model by Ujhazy, P, Chen, Y F, Fredericks, W, Ho, R L, Mihich, E, Baker, R M, Ehrke, M J

“…A number of recent studies have implied that a relationship exists between cellular sensitivities to tumor necrosis factor (TNF) and expression of the classic…”
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