Search Results - "Ho, Peiying"
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An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis
Published in Nature communications (11-07-2023)“…Bacteria possess elaborate systems to manage reactive oxygen and nitrogen species (ROS) arising from exposure to the mammalian immune system and environmental…”
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Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis
Published in Nature communications (07-12-2017)“…Pyruvate kinase (PYK) is an essential glycolytic enzyme that controls glycolytic flux and is critical for ATP production in all organisms, with tight…”
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Screening of the PA14NR Transposon Mutant Library Identifies Genes Involved in Resistance to Bacteriophage Infection in Pseudomomas aeruginosa
Published in International journal of molecular sciences (26-06-2024)“…Multidrug-resistant infections pose a serious public health threat due to the rise in antimicrobial resistance. Phage therapy has emerged as a promising…”
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Hydrogen Sulfide Sensitizes Acinetobacter baumannii to Killing by Antibiotics
Published in Frontiers in microbiology (07-08-2020)“…The production of endogenous hydrogen sulfide (H 2 S) has been shown to confer antibiotic tolerance in all bacteria studied to date. Therefore, this mediator…”
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Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats
Published in Journal of applied physiology (1985) (01-01-2007)“…Departments of 1 Pharmacology and 2 Biochemistry, National University of Singapore, Singapore; 3 Departments of Physiology and Pathophysiology, and 4…”
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Regulatory T cells induced by Mycobacterium chelonae sensitization influence murine responses to bacille Calmette-Guérin
Published in Journal of leukocyte biology (01-12-2010)“…5CD4+CD25+ cells in Mycobacterium chelonae‐sensitized mice functionally suppress BCG‐induced inflammation, providing one explanation for how immune priming by…”
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Dermatoscopic features of cutaneous metastasis in advanced gastric cancer
Published in JAAD Case Reports (01-05-2022)Get full text
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Erythematous scaly plaques and nodules on scalp
Published in Dermatology online journal (15-10-2023)“…Cutaneous manifestations of syphilis are varied and may present with non-specific features. We describe a 45-year-old man who presented with erythematous scaly…”
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Design of Biodegradable, Climate-Specific Packaging Materials That Sense Food Spoilage and Extend Shelf Life
Published in ACS nano (09-05-2023)“…The AgriFood systems in tropical climates are under strain due to a rapid increase in human population and extreme environmental conditions that limit the…”
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Production of Superoxide in Bacteria Is Stress- and Cell State-Dependent: A Gating-Optimized Flow Cytometry Method that Minimizes ROS Measurement Artifacts with Fluorescent Dyes
Published in Frontiers in microbiology (21-03-2017)“…The role of reactive oxygen species (ROS) in microbial metabolism and stress response has emerged as a major theme in microbiology and infectious disease…”
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Electrostatic microfiltration (EM) enriches and recovers viable microorganisms at low-abundance in large-volume samples and enhances downstream detection
Published in Lab on a chip (10-09-2024)“…Rapid and sensitive detection of pathogens in various samples is crucial for disease diagnosis, environmental surveillance, as well as food and water safety…”
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The absence of the queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12
Published in Metallomics (24-09-2022)“…Queuosine (Q) is a conserved hypermodification of the wobble base of tRNA containing GUN anticodons but the physiological consequences of Q deficiency are…”
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Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish
Published in JAC-antimicrobial resistance (01-06-2023)“…Abstract Background Mycobacterium abscessus is a non-tuberculous mycobacterium (NTM) that causes chronic pulmonary infections. Because of its extensive innate…”
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Mycobacterium chelonae sensitisation induces CD4⁺-mediated cytotoxicity against BCG
Published in European journal of immunology (01-07-2009)“…Significant variability in efficacy of live Mycobacterium bovis BCG as a tuberculosis vaccine is observed globally. Effects of pre-vaccination sensitisation to…”
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inPhocus: Current State and Challenges of Phage Research in Singapore
Published in PHAGE (Print) (01-03-2022)“…Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage…”
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Mycobacterium chelonae sensitisation induces CD4 super(+)-mediated cytotoxicity against BCG
Published in European journal of immunology (01-07-2009)“…Significant variability in efficacy of live Mycobacterium bovis BCG as a tuberculosis vaccine is observed globally. Effects of pre-vaccination sensitisation to…”
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COVID 19: prioritise autonomy, beneficence and conversations before score-based triage
Published in Age and ageing (08-01-2021)“…Abstract At the start of the COVID-19 pandemic, mounting demand overwhelmed critical care surge capacities, triggering implementation of triage protocols to…”
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Survey highlights important discrepancies between definitions of paediatric abnormal growth taught to medical students in 23 European countries
Published in Acta Paediatrica (01-07-2018)“…Aim This study compared the definitions of abnormal growth that are taught across Europe to explain previously reported variations in growth‐monitoring…”
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Setting Goals or Shifting Goalposts: Role of Frailty for Critical Care Decisions During COVID-19
Published in The Journal of frailty & aging (01-10-2020)“…Whilst the multidimensional measure of frailty such as Clinical Frailty Scale (CFS) and Frailty Index (FI) generally predict higher hospital mortality, longer…”
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