Search Results - "Ho, Leona T Y"

Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells by Ho, Leona T Y, Skiba, Nikolai, Ullmer, Christoph, Rao, Ponugoti Vasantha

“…Lysophosphatidic acid (LPA), a bioactive lipid, has been shown to increase resistance to aqueous humor outflow (AH) through the trabecular meshwork (TM). The…”
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Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment by Chua, Xin Ying, Ho, Leona T. Y., Xiang, Ping, Chew, Wee Siong, Lam, Brenda Wan Shing, Chen, Christopher P., Ong, Wei-Yi, Lai, Mitchell K. P., Herr, Deron R.

“…Sphingosine 1-phosphates (S1Ps) are bioactive lipids that mediate a diverse range of effects through the activation of cognate receptors, S1P 1 –S1P 5 …”
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Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy by Okumura, Naoki, Minamiyama, Ryuki, Ho, Leona TY, Kay, EunDuck P, Kawasaki, Satoshi, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich E, Young, Robert D, Quantock, Andrew J, Kinoshita, Shigeru, Koizumi, Noriko

“…Fuchs endothelial corneal dystrophy (FECD) due to corneal endothelial cell degeneration is a major cause of corneal transplantation. It is characterized by…”
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Influence of Growth Differentiation Factor 15 on Intraocular Pressure in Mice by Maddala, Rupalatha, Eldawy, Camelia, Ho, Leona T.Y., Challa, Pratap, Rao, Ponugoti V.

“…Growth differentiation factor 15 (GDF15), a stress-sensitive cytokine, and a distant member of the transforming growth factor β superfamily, has been shown to…”
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Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity by Ho, Leona T.Y., Osterwald, Anja, Ruf, Iris, Hunziker, Daniel, Mattei, Patrizio, Challa, Pratap, Vann, Robin, Ullmer, Christoph, Rao, Ponugoti Vasanth

“…Ocular hypertension due to impaired aqueous humor (AH) drainage through the trabecular meshwork (TM) is a major risk factor for glaucoma, a leading cause of…”
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A comparison of glycosaminoglycan distributions, keratan sulphate sulphation patterns and collagen fibril architecture from central to peripheral regions of the bovine cornea by Ho, Leona T.Y., Harris, Anthony M., Tanioka, Hidetoshi, Yagi, Naoto, Kinoshita, Shigeru, Caterson, Bruce, Quantock, Andrew J., Young, Robert D., Meek, Keith M.

“…This study investigated changes in collagen fibril architecture and the sulphation status of keratan sulphate (KS) glycosaminoglycan (GAG) epitopes from…”
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Elevated Levels of Growth/Differentiation Factor-15 in the Aqueous Humor and Serum of Glaucoma Patients by Maddala, Rupalatha, Ho, Leona T Y, Karnam, Shruthi, Navarro, Iris, Osterwald, Anja, Stinnett, Sandra S, Ullmer, Christoph, Vann, Robin R, Challa, Pratap, Rao, Ponugoti V

“…Dysregulated levels of growth/differentiation factor-15 (GDF15), a divergent member of the transforming growth factor-beta super family, have been found to be…”
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