Search Results - "Ho, Hsiang‐Ling"
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AKT1 internal tandem duplications and point mutations are the genetic hallmarks of sclerosing pneumocytoma
Published in Modern pathology (01-03-2020)“…Sclerosing pneumocytoma is a unique benign neoplasm of the lungs. The molecular alterations in sclerosing pneumocytoma are not well understood. In a previous…”
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2
Efficacy of liquid biopsy for disease monitoring and early prediction of tumor progression in EGFR mutation-positive non-small cell lung cancer
Published in PloS one (28-04-2022)“…15-40% of non-small cell lung cancer (NSCLC) patients harbor epidermal growth factor receptor (EGFR)-sensitizing mutations. Tyrosine kinase inhibitors (TKIs)…”
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3
The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma
Published in PloS one (16-10-2017)“…Promoter methylation is the most significant mechanism to regulate O6-methylguanine-DNA-methyltransferase (MGMT) expression. Single-nucleotide polymorphisms…”
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4
Dynamic Assessment of Tissue and Plasma EGFR-Activating and T790M Mutations with Droplet Digital PCR Assays for Monitoring Response and Resistance in Non-Small Cell Lung Cancers Treated with EGFR-TKIs
Published in International journal of molecular sciences (26-09-2022)“…Assessing tumor EGFR mutation status is necessary for the proper management of patients with advanced non–small cell lung cancer (NSCLC). We evaluated the…”
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5
Gene Expression Profile in Primary Tumor Is Associated with Brain-Tropism of Metastasis from Lung Adenocarcinoma
Published in International journal of molecular sciences (13-12-2021)“…Lung adenocarcinoma has a strong propensity to metastasize to the brain. The brain metastases are difficult to treat and can cause significant morbidity and…”
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Loss of BCAT1 Expression is a Sensitive Marker for IDH-Mutant Diffuse Glioma
Published in Neurosurgery (01-09-2019)“…BACKGROUND:IDH mutation is an important prognostic factor of diffuse astrocytomas. Although the majority of IDH mutations could be identified by…”
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Detection of human cytomegalovirus in glioblastoma among Taiwanese subjects
Published in PloS one (08-06-2017)“…The relationship between human cytomegalovirus (HCMV) and glioblastoma (GBM) has been debated for more than a decade. We investigated the presence of HCMV…”
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Diffuse Intratumoral Stromal Inflammation in Ovarian Clear Cell Carcinoma is Associated With Loss of Mismatch Repair Protein and High PD-L1 Expression
Published in International journal of gynecological pathology (01-03-2021)“…Ovarian clear cell carcinoma (OCCC) is an aggressive chemotherapy-resistant cancer with limited treatment options, and some OCCCs have mismatch repair (MMR)…”
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PD-L1 is a double-edged sword in colorectal cancer: the prognostic value of PD-L1 depends on the cell type expressing PD-L1
Published in Journal of cancer research and clinical oncology (01-07-2019)“…Purpose To investigate the associations between programmed cell death ligand-1 (PD-L1) on tumor cells (TCs) or PD-L1 on tumor-infiltrating immune cells (TIICs)…”
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10
Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients
Published in American journal of clinical pathology (29-03-2018)“…Abstract Objectives To evaluate the prognostic values of microRNAs (miRNAs) in glioblastoma, and to see if there is an association between miRNAs and MGMT…”
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Efficacy of different platforms in detecting EGFR mutations using cerebrospinal fluid cell‐free DNA from non‐small‐cell lung cancer patients with leptomeningeal metastases
Published in Thoracic cancer (01-05-2023)“…Background Cell‐free tumor DNA (ctDNA) obtained through liquid biopsy is useful for the molecular analysis of advanced non‐small‐cell lung cancer (NSCLC). Few…”
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12
The importance of EGFR mutation testing in squamous cell carcinoma or non-small cell carcinoma favor squamous cell carcinoma diagnosed from small lung biopsies
Published in Diagnostic pathology (21-06-2019)“…Adenosquamous carcinoma (ADSC) of the lung, a rare but aggressive subtype of non-small cell lung cancer (NSCLC), is defined as a carcinoma containing…”
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13
Assuring safety of fecal microbiota transplantation in the COVID‐19 era: A single‐center experience
Published in JGH open (01-11-2023)“…Background and Aim Fecal microbiota transplantation (FMT) is used to treat recurrent or refractory Clostridioides difficile infection (CDI). In the past,…”
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14
Programmed death‐ligand 1 (PD‐L1)/thyroid transcription factor‐1 double immunohistochemical staining facilitates scoring of tumor PD‐L1 expression in cytopathology specimens from lung adenocarcinoma patients
Published in Cancer cytopathology (01-02-2021)“…Background Immune checkpoint inhibitor therapy has revolutionized lung adenocarcinoma therapy. Treatment with antibodies against the immune checkpoint…”
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15
Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma Progression
Published in International journal of molecular sciences (17-09-2020)“…Nicotine in tobacco smoke is considered carcinogenic in several malignancies including lung cancer. The high incidence of lung adenocarcinoma (LAC) in…”
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16
Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Somatic Mutations in CDH1 and Other Clinically Actionable Mutations Imply Early Use of Targeted Agents
Published in Current oncology (Toronto) (16-02-2021)“…Primary signet ring cell/histiocytoid carcinoma of the eyelid is a rare ocular malignancy and its diagnosis is often delayed. This neoplasm presents as an…”
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Molecular typing for detection of high-risk human papillomavirus is a useful tool for distinguishing primary bladder carcinoma from secondary involvement of uterine cervical carcinoma in the urinary bladder
Published in Histopathology (01-03-2016)“…Aims For patients with carcinoma of the urinary bladder and uterine cervix, distinguishing between metastasis and a second primary carcinoma has significant…”
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Seroprevalence of COVID-19 in Taiwan revealed by testing anti-SARS-CoV-2 serological antibodies on 14,765 hospital patients
Published in The Lancet regional health. Western Pacific (01-10-2020)“…Coronavirus Disease 2019 (COVID-19) has become a worldwide pandemic and affected more than 227 countries or territories, resulting in more than 25 million…”
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Comparative Assessment of 4 Methods to Analyze MGMT Status in a Series of 121 Glioblastoma Patients
Published in Applied immunohistochemistry & molecular morphology (01-08-2017)“…The O-methylguanine-DNA-methyltranferase (MGMT) status is a powerful predictor of response to temozolomide for newly diagnosed glioblastoma (GBM) patients, and…”
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Characterization of Collapsin Response Mediator Protein 2 in Colorectal Cancer Progression in Subjects with Diabetic Comorbidity
Published in Cells (Basel, Switzerland) (18-02-2022)“…Common demographic risk factors are identified in colorectal cancer (CRC) and type 2 diabetes mellitus (DM), nevertheless, the molecular link and mechanism for…”
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