Search Results - "Ho, Holly H"
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Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin
Published in Biochemistry (Easton) (22-08-1989)“…Combretastatin A-4 (CS-A4), 3,4,5-trimethoxy-3'-hydroxy-4'-methoxy-(Z)-stilbene, and combretastatin A-2 (CS-A2),…”
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Tubulin-dependent hydrolysis of guanosine triphosphate as a screening test to identify new antitubulin compounds with potential as antimitotic agents: application to carbamates of aromatic amines
Published in Cancer research (Chicago, Ill.) (15-03-1989)“…Tubulin-dependent GTP hydrolysis was evaluated for its potential as a relatively simple screening assay for new antimitotic drugs. Carbamates of aromatic…”
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Adsorbing Colloid Flotation of Heavy Metal Ions from Aqueous Solutions at Large Ionic Strength
Published in Environmental science & technology (01-07-1995)“…Adsorbing colloid flotation removes various heavy metal ions from wastewater at large ionic strength. By eliminating the greatest drawback of adsorbing colloid…”
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Cornigerine, a potent antimitotic Colchicum alkaloid of unusual structure. Interactions with tubulin
Published in Biochemical pharmacology (15-06-1988)“…Cornigerine is a natural product analog of colchicine produced by Colchicum cornigerum in which the vicinal 2- and 3-methoxy groups are condensed into a…”
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Critical amount of oligovalent Ion binding required for the B-Z transition of poly (dG-m5dC)
Published in Nucleic acids research (12-03-1984)“…By working at very low Na+ concentrations (1mM and less), the number of bound Mg(2+), cobalt hexamine(3+), and spermine(4+) necessary to induce the B-Z…”
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Structure of A-DNA in Solution
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1987)“…The structure of DNA in aqueous trifluoroethanol solutions containing more than 70% (vol/vol) trifluoroethanol, where it has been proposed to have the…”
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