Search Results - "Ho, D."
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1
Antibody Response to Omicron BA.4–BA.5 Bivalent Booster
Published in The New England journal of medicine (09-02-2023)“…In a small study, a bivalent mRNA vaccine targeting omicron BA.4–BA.5 sublineages resulted in similar neutralization of other SARS-CoV-2 variants as a fourth…”
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Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization
Published in Cell host & microbe (12-05-2021)“…The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to antibody-mediated immunity. The relative resistance of SARS-CoV-2…”
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3
Epigenetics and transgenerational transfer: a physiological perspective
Published in Journal of experimental biology (01-01-2010)“…Epigenetics, the transgenerational transfer of phenotypic characters without modification of gene sequence, is a burgeoning area of study in many disciplines…”
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4
Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5
Published in Nature (London) (18-08-2022)“…SARS-CoV-2 Omicron subvariants BA.2.12.1 and BA.4/5 have surged notably to become dominant in the United States and South Africa, respectively 1 , 2 . These…”
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Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7
Published in Nature (London) (06-05-2021)“…The COVID-19 pandemic has had widespread effects across the globe, and its causative agent, SARS-CoV-2, continues to spread. Effective interventions need to be…”
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6
Antibody evasion properties of SARS-CoV-2 Omicron sublineages
Published in Nature (London) (21-04-2022)“…The identification of the Omicron (B.1.1.529.1 or BA.1) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 1…”
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7
Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies
Published in PLoS biology (12-07-2021)“…SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level persistent viral RNA shedding. The…”
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Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir
Published in Nature (London) (19-01-2023)“…Nirmatrelvir, an oral antiviral targeting the 3CL protease of SARS-CoV-2, has been demonstrated to be clinically useful against COVID-19 (refs. 1 , 2 )…”
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A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Published in Cell stem cell (02-07-2020)“…SARS-CoV-2 has caused the COVID-19 pandemic. There is an urgent need for physiological models to study SARS-CoV-2 infection using human disease-relevant cells…”
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10
Human haematopoietic stem cell lineage commitment is a continuous process
Published in Nature cell biology (01-04-2017)“…Blood formation is believed to occur through stepwise progression of haematopoietic stem cells (HSCs) following a tree-like hierarchy of oligo-, bi- and…”
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11
Numerical study of the bolt-grout interface for fully grouted rockbolt under different confining conditions
Published in International journal of rock mechanics and mining sciences (Oxford, England : 1997) (01-07-2019)“…This paper presents a numerical approach to study the bolt-grout interface of fully grouted rockbolts. Two series of pull-out tests of short-length rockbolts…”
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12
Indirect optical trapping using light driven micro-rotors for reconfigurable hydrodynamic manipulation
Published in Nature communications (14-03-2019)“…Optical tweezers are a highly versatile tool for exploration of the mesoscopic world, permitting non-contact manipulation of nanoscale objects. However, direct…”
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13
Saliva as a diagnostic specimen for testing respiratory virus by a point-of-care molecular assay: a diagnostic validity study
Published in Clinical microbiology and infection (01-03-2019)“…Automated point-of-care molecular assays have greatly shortened the turnaround time of respiratory virus testing. One of the major bottlenecks now lies at the…”
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14
A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis
Published in Blood (09-10-2014)“…The kidney is involved in 70% of patients with immunoglobulin light-chain (AL) amyloidosis, but little is known on progression or reversibility of renal…”
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15
Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated Persons
Published in The New England journal of medicine (23-12-2021)“…A SARS-CoV-2 surveillance program conducted by the National Basketball Association identified 173 newly infected persons. The viral kinetics were…”
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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Published in Nature (London) (14-01-2021)“…There is an urgent need to create novel models using human disease-relevant cells to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) biology…”
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17
Antigenic characterization of the SARS-CoV-2 Omicron subvariant BA.2.75
Published in Cell host & microbe (09-11-2022)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant BA.2.75 emerged recently and appears to be spreading. It has nine mutations…”
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Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations
Published in Blood (20-09-2018)“…SF3B1, SRSF2, and U2AF1 are the most frequently mutated splicing factor genes in the myelodysplastic syndromes (MDS). We have performed a comprehensive and…”
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19
Chaotic Properties of a Turbulent Isotropic Fluid
Published in Physical review letters (12-01-2018)“…By tracking the divergence of two initially close trajectories in phase space in an Eulerian approach to forced turbulence, the relation between the maximal…”
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20
Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike
Published in Nature (London) (21-12-2023)“…A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant, BA.2.86, has emerged and spread to numerous countries worldwide, raising…”
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