Search Results - "Ho, Amy S W"
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Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways
Published in Neuro-oncology (Charlottesville, Va.) (01-05-2013)“…Glioblastoma multiforme (GBM), the most aggressive malignant primary brain tumor of the central nervous system, is characterized by a relentless disease…”
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Comparison between self‐assembling peptide nanofiber scaffold (SAPNS) and fibrin sealant in neurosurgical hemostasis
Published in Clinical and translational science (01-10-2015)“…RADA16‐I is a synthetic type I self‐assembling peptide nanofiber scaffold (SAPNS) which may serve as a novel biocompatible hemostatic agent. Its application in…”
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Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling
Published in Oncotarget (22-09-2017)“…Endoplasmic reticulum (ER) chaperone Prolyl 4-hydroxylase, beta polypeptide (P4HB) has previously been identified as a novel target for chemoresistance in…”
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Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response
Published in Anticancer research (01-06-2014)“…Intratumoural hypoxia is associated with chemoresistance in glioblastoma multiforme (GBM), a highly malignant brain tumour. Adaptive response to endoplasmic…”
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Effects of progesterone vs. dexamethasone on brain oedema and inflammatory responses following experimental brain resection
Published in Brain injury (01-11-2014)“…Abstract Background: Dexamethasone (DEXA) is commonly used to reduce brain swelling during neurosurgical procedures. DEXA, however, has many side-effects that…”
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MicroRNA-210 and Endoplasmic Reticulum Chaperones in the Regulation of Chemoresistance in Glioblastoma
Published in Journal of Cancer (01-01-2015)“…Glioblastoma multiforme (GBM) is the commonest primary brain tumour in adults characterized by relentless recurrence due to resistance towards the standard…”
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CS-17 UPREGULATION OF THE ENDOPLASMIC RETICULUM CHAPERONE, PROLYL 4-HYDROXYLASE, BETA POLYPEPTIDE (P4HB) PROMOTES INVASION, ANGIOGENESIS AND GROWTH VIA EGFR/MAPK (ERK) SIGNALLING PATHWAY IN MALIGNANT GLIOMA
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2014)“…BACKGROUND: Tumor invasion and vascularization are typical hallmarks in malignant glioma with the majority showing elevated expression and activation of the…”
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