Search Results - "Ho, A W"

Combined treatment of Nimotuzumab and rapamycin is effective against temozolomide-resistant human gliomas regardless of the EGFR mutation status by Chong, Dawn Q, Toh, Xin Y, Ho, Ivy A W, Sia, Kian C, Newman, Jennifer P, Yulyana, Yulyana, Ng, Wai-Hoe, Lai, Siang H, Ho, Mac M F, Dinesh, Nivedh, Tham, Chee K, Lam, Paula Y P

“…The treatment of glioblastoma multiforme (GBM) is an unmet clinical need. The 5-year survival rate of patients with GBM is less than 3%. Temozolomide (TMZ)…”
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Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme by Newman, Jennifer P., Wang, Grace Y., Arima, Kazuhiko, Guan, Shou P., Waters, Michael R., Cavenee, Webster K., Pan, Edward, Aliwarga, Edita, Chong, Siao T., Kok, Catherine Y. L., Endaya, Berwini B., Habib, Amyn A., Horibe, Tomohisa, Ng, Wai H., Ho, Ivy A. W., Hui, Kam M., Kordula, Tomasz, Lam, Paula Y. P.

“…The interleukin-13 receptor alpha2 (IL-13Rα2) is a cancer-associated receptor overexpressed in human glioblastoma multiforme (GBM). This receptor is…”
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Contribution of the Microenvironmental Niche to Glioblastoma Heterogeneity by Ho, Ivy A. W., Shim, Winston

“…Glioblastoma is the most aggressive cancer of the brain. The dismal prognosis is largely attributed to the heterogeneous nature of the tumor, which in addition…”
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Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling by Yulyana, Yulyana, Ho, Ivy A W, Sia, Kian Chuan, Newman, Jennifer P, Toh, Xin Yi, Endaya, Berwini B, Chan, Jerry K Y, Gnecchi, Massimiliano, Huynh, Hung, Chung, Alexander Y F, Lim, Kiat Hon, Leong, Hui Sun, Iyer, Narayanan Gopalakrishna, Hui, Kam Man, Lam, Paula Y P

“…Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death in the world. The multikinase inhibitor sorafenib only demonstrated marginal…”
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Matrix Metalloproteinase 1 Is Necessary for the Migration of Human Bone Marrow‐Derived Mesenchymal Stem Cells Toward Human Glioma by Ho, Ivy A. W., Chan, Kelly Y. W., Ng, Wai‐Hoe, Guo, Chang M., Hui, Kam M., Cheang, Philip, Lam, Paula Y. P.

“…Human mesenchymal stem cells (MSCs) have increasingly been used as cellular vectors for the delivery of therapeutic genes to tumors. However, the precise…”
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Human Bone Marrow‐Derived Mesenchymal Stem Cells Suppress Human Glioma Growth Through Inhibition of Angiogenesis by Ho, Ivy A.W., Toh, Han C, Ng, Wai H., Teo, Yuan L., Guo, Chang M., Hui, Kam M., Lam, Paula Y.P.

“…Tumor tropism of human bone marrow‐derived mesenchymal stem cells (MSC) has been exploited for the delivery of therapeutic genes for anticancer therapy…”
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Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness by Fadhlullah, Siti Farah Bte, Halim, Nurashikin Bte Abdul, Yeo, Jacqueline Y. T., Ho, Rachel L. Y., Um, Phoebe, Ang, Beng Ti, Tang, Carol, Ng, Wai H., Virshup, David M., Ho, Ivy A. W.

“…Glioblastoma (GBM) is the most aggressive tumor of the brain. NF1 , a tumor suppressor gene and RAS-GTPase, is one of the highly mutated genes in GBM…”
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Relationship of Stress, Distress, and Inadequate Coping Behaviors to Periodontal Disease by Genco, R.J., Ho, A.W., Grossi, S.G., Dunford, R.G., Tedesco, L.A.

“…Background: The association of stress, distress, and coping behaviors with periodontal disease was assessed. Methods: A cross‐sectional study of 1,426 subjects…”
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Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen by TAN, K, CHEANG, P, HO, I. A. W, LAM, P. Y. P, HUI, K. M

“…We have compared the ability of several nanosized bioceramic particles including negatively charged silica (SiO(2)), neutrally charged hydroxyapatite (HA) and…”
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Aberrant activation profile of cytokines and mitogen-activated protein kinases in type 2 diabetic patients with nephropathy by Wong, C.K, Ho, A.W.Y, Tong, P.C.Y, Yeung, C.Y, Kong, A.P.S, Lun, S.W.M, Chan, J.C.N, Lam, C.W.K

“…Cytokine-induced inflammation is involved in the pathogenesis of type 2 diabetes mellitus (DM). We investigated plasma concentrations and ex vivo production of…”
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Response to: Infective endocarditis and its neurological complications by Wang, P -E, Sia, C -H, Ho, A F -W, Tan, B Y -Q

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Matrix metalloproteinase‐1‐mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C‐X‐C chemokine receptor 4 axis by Ho, Ivy A. W., Yulyana, Yulyana, Sia, Kian C., Newman, Jennifer P., Guo, Chang M., Hui, Kam M., Lam, Paula Y. P.

“…Human bone marrow‐derived mesenchymal stem cells (MSCs) have the unique ability to home toward injuries or tumor sites. We have previously shown that the…”
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Isolation of peptide ligands that interact specifically with human glioma cells by Ho, Ivy A.W., Hui, Kam M., Lam, Paula Y.P.

“…Poor prognosis of high grade gliomas coupled with the difficulty of widespread delivery of therapeutic agents prompted the search into new molecular targets…”
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Angiopoietin: A TIE(d) Balance in Tumor Angiogenesis by Shim, Winston S N, Ho, Ivy A W, Wong, Philip E H

“…Angiopoietins (ANG-1 and ANG-2) and their TIE-2 receptor tyrosine kinase have wide-ranging effects on tumor malignancy that includes angiogenesis,…”
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Hybrid herpes simplex virus/Epstein-Barr virus amplicon viral vectors confer enhanced transgene expression in primary human tumors and human bone marrow-derived mesenchymal stem cells by Sia, Kian Chuan, Chong, Wei Kin, Ho, Ivy A. W., Yulyana, Yulyana, Endaya, Berwini, Huynh, Hung, Lam, Paula Y. P.

“…Background Herpes simplex virus type‐1 (HSV‐1) amplicon vectors are attractive tools for gene transfer because of their large DNA insert capacity, their broad…”
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Recent Advances in Glioma Therapy: Combining Vascular Normalization and Immune Checkpoint Blockade by Ho, Rachel L. Y., Ho, Ivy A. W.

“…Glioblastoma (GBM) accounts for more than 50% of all primary malignancies of the brain. Current standard treatment regimen for GBM includes maximal surgical…”
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Targeting human glioma cells using HSV-1 amplicon peptide display vector by Ho, I A W, Miao, L, Sia, K C, Wang, G Y, Hui, K M, Lam, P Y P

“…Targeting cell infection using herpes simplex virus type 1 (HSV-1) vectors is a complicated issue as the process involves multiple interactions of viral…”
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Potential Associations Between Chronic Respiratory Disease and Periodontal Disease: Analysis of National Health and Nutrition Examination Survey III by Scannapieco, Frank A., Ho, Alex W.

“…Background: Associations between poor oral health and chronic lung disease have recently been reported. The present study evaluated these potential…”
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Global resuscitation alliance utstein recommendations for developing emergency care systems to improve cardiac arrest survival by Nadarajan, G.D., Tiah, L., Ho, A.F.W., Azazh, A., Castren, M.K., Chong, S.L., El Sayed, M.J., Hara, T., Leong, B.S., Lippert, F.K., Ma, M.H.M., Ng, Y.Y., Ohn, H.M., Overton, J., Pek, P.P., Perret, S., Wallis, L.A, Wong, K.D., Ong, M.E.H.

“…The Global Resuscitation Alliance (GRA) was established in 2015 to improve survival for Out- of-Hospital Cardiac Arrest (OHCA) using the best practices…”
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Assessment of risk for periodontal disease. II. Risk indicators for alveolar bone loss by Grossi, S G, Genco, R J, Machtei, E E, Ho, A W, Koch, G, Dunford, R, Zambon, J J, Hausmann, E

“…This study examined the risk indicators for alveolar bone loss associated with periodontal infection. A cross-section of 1,361 subjects aged 25 to 74 years,…”
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