Search Results - "Hmitou, Isabelle"
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Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells
Published in Nature (London) (04-02-2016)“…Genome-wide binding profiles for eight different chromatin remodellers in mouse embryonic stem (ES) cells are determined at single nucleosome resolution; each…”
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Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation
Published in The Journal of clinical investigation (01-10-2010)“…Accumulating evidence points to inflammation as a promoter of carcinogenesis. MyD88 is an adaptor molecule in TLR and IL-1R signaling that was recently…”
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Mammalian target of rapamycin inhibition counterbalances the inflammatory status of immune cells in patients with chronic granulomatous disease
Published in Journal of allergy and clinical immunology (01-05-2017)“…Background Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defective production of reactive oxygen species in phagocytic cells that…”
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Differential Regulation of B-Raf Isoforms by Phosphorylation and Autoinhibitory Mechanisms
Published in Molecular and Cellular Biology (01-01-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse
Published in PloS one (22-12-2010)“…The B-raf proto-oncogene exerts essential functions during development and adulthood. It is required for various processes, such as placental development,…”
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Optimizing CD4+ T-Cells Transduction Protocol for Gene Therapy of HIV-1 Infected Patients
Published in Blood (03-12-2015)“…Gene therapy represents an alternative and promising strategy that could provide a path to a curative therapy for HIV-1 infection. One approach involves the…”
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Small GTP-binding proteins and their regulators in cardiac hypertrophy
Published in Journal of molecular and cellular cardiology (01-04-2008)“…Abstract Small GTP-binding proteins (small G proteins) act as GDP–GTP-regulated molecular switches and are activated by guanine nucleotide exchange factors…”
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Efficient Depletion of Essential Gene Products for Loss-of-Function Studies in Embryonic Stem Cells
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…The development of the CRISPR/Cas9 technology has provided powerful methods to target genetic alterations. However, investigating the function of genes…”
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225. Preserving CD4+ T-Cells Phenotype and Function Upon Ex Vivo Lentiviral Transduction
Published in Molecular therapy (01-05-2016)Get full text
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Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway
Published in Cellular signalling (01-10-2010)“…Epac (Exchange protein directly activated by cAMP) is a sensor for cAMP and represents a novel mechanism for governing cAMP signalling. Epac is a guanine…”
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11
Differential Regulation of B-Raf Isoforms by Phosphorylation and AutoinhibitoryMechanisms
Published in Molecular and cellular biology (01-01-2007)“…The B-Raf proto-oncogene encodes several isoforms resulting from alternative splicing in the hinge region upstream of the kinase domain. The presence of exon…”
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