Search Results - "Hlobilková, Alice"

Nestin expression in cutaneous melanomas and melanocytic nevi by Brychtova, Svetlana, Fiuraskova, Michala, Hlobilková, Alice, Brychta, Tomas, Hirnak, Jaroslav

“…Background:  Nestin is one of the intermediate filaments that are expressed in proliferating neural progenitor cells during development of the central nervous…”
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Synthesis and biological activity of 8-azapurine and pyrazolo[4,3- d]pyrimidine analogues of myoseverin by Kryštof, Vladimír, Moravcová, Daniela, Paprskářová, Martina, Barbier, Pascale, Peyrot, Vincent, Hlobilková, Alice, Havlíček, Libor, Strnad, Miroslav

“…The trisubstituted purine myoseverin has been recently identified as a novel inhibitor of microtubule assembly. To analyze the effects of modifying its…”
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Autocrine regulation of glioblastoma cell-cycle progression, viability and radioresistance through the VEGF-VEGFR2 (KDR) interplay by Knizetova, Petra, Ehrmann, Jiri, Hlobilkova, Alice, Vancova, Iveta, Kalita, Ondrej, Kolar, Zdenek, Bartek, Jiri

“…Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis and progression of malignant brain tumors. Given the significance of tumor…”
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Triple negative breast cancer - BCL2 in prognosis and prediction. Review by Bouchalova, Katerina, Kharaishvili, Gvantsa, Bouchal, Jan, Vrbkova, Jana, Megova, Magdalena, Hlobilkova, Alice

“…Breast cancer (BC), the most frequent malignancy in women worldwide, is currently diagnosed in about 1.4 million female patients annually. Approximately 10-20%…”
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The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP by Bouchal, Jan, Kolář, Zdeněk, Mad’arová, Jana, Hlobilková, Alice, von Angerer, Erwin

“…The effects of the 17β-estradiol, dihydrotestosterone and hormone antagonists tamoxifen and bicalutamide on telomerase activity and expression of cell cycle…”
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Tumour Suppressor PTEN Regulates Cell Cycle and Protein Kinase B/Akt Pathway in Breast Cancer Cells by HLOBILKOVA, Alice, KNILLOVA, Jana, SVACHOVA, Michaela, SKYPALOVA, Petra, KRYSTOF, Vladimir, KOLAR, Zdenek

“…Background: PTEN is a tumour suppressor protein with phosphatase activity frequently altered in several types of human cancers. Materials and Methods: The PTEN…”
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Molecular Changes in PDEGF and bFGF in Malignant Melanomas in Relation to the Stromal Microenvironment by FIURASKOVA, Michala, BRYCHTOVA, Svetlana, SEDLAKOVA, Eva, BENES, Petr, ZALESAK, Bohumil, HLOBILKOVA, Alice, TICHY, Martin, KOLAR, Zdenek

“…Background: Aberrant expression of either growth factors or growth factor-receptors by stromal cells can be an important factor promoting the growth of solid…”
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The mechanism of action of the tumour suppressor gene PTEN by Hlobilková, Alice, Knillová, Jana, Bártek, Jirí, Lukás, Jirí, Kolár, Zdenek

“…Intracellular levels of phosphorylation are regulated by the coordinated action of protein kinases and phosphatases. Disregulation of this balance can lead to…”
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Effects of sanguinarine and chelerythrine on the cell cycle and apoptosis by Malikova, Jana, Zdarilova, Adela, Hlobilkova, Alice

“…This review summarizes the involvement of sanguinarine and chelerythrine in cell cycle regulation and cell death in various cell lines. It is focused on their…”
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THE SIGNIFICANCE OF KEY REGULATORS OF APOPTOSIS IN THE DEVELOPMENT AND PROGNOSIS OF PROSTATE CARCINOMA. II. PRODUCTS OF SUPPRESSOR GENES RB AND PTEN, CDKI, FAS by Knillová, Jana, Kolář, Zdeněk, Hlobilková, Alice

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Glioblastoma multiforme with an abscess: case report and literature review by Kalita, Ondrej, Kala, Miroslav, Svebisova, Hana, Ehrmann, Jiri, Hlobilkova, Alice, Trojanec, Radek, Hajduch, Marian, Houdek, Michael

“…An intratumoral or peritumoral microbial intracranial abscess is an infrequent diagnosis. The development of this complication may not be preceded by apparent…”
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Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells by Priwitzerova, Monika, Pospisilova, Dagmar, Prchal, Josef T., Indrak, Karel, Hlobilkova, Alice, Mihal, Vladimir, Ponka, Prem, Divoky, Vladimir

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The significance of key regulators of apoptosis in the development and prognosis of prostate carcinoma. II. Products of suppressor genes Rb and PTEN, CDKI, Fas by Knillová, Jana, Kolár, Zdenek, Hlobilková, Alice

“…The molecular basis for the transition of carcinoma of the prostate from androgen-dependent to androgen-independent growth is largely unknown. Currently for…”
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Immunohistochemical assessment of E-cadherin and beta-catenin in trichofolliculomas and trichoepitheliomas by Bezdekova, Michala, Brychtova, Svetlana, Sedlakova, Eva, Steigerova, Jana, Hlobilkova, Alice, Bienova, Martina, Kucerova, Renata, Brychta, Tomas, Krejci, Veronika, Kolar, Zdenek

“…Trichofolliculomas and trichoepitheliomas are benign skin neoplasms originating from hair follicle cells. They result from defects in the signaling pathways…”
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Cell Cycle Arrest by the PTEN Tumor Suppressor Is Target Cell Specific and May Require Protein Phosphatase Activity by Hlobilkova, Alice, Guldberg, Per, Thullberg, Minna, Zeuthen, Jesper, Lukas, Jiri, Bartek, Jiri

“…PTEN, a tumor suppressor commonly targeted in human cancer, possesses phosphatase activities toward both protein and lipid substrates. While PTEN suppresses…”
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Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin-dependent kinase inhibitor olomoucine by Hajdúch, M, Kolár, Z, Novotný, R, Hanus, J, Mihál, V, Hlobílková, A, Nosková, V, Strnad, M

“…This case report describes a dog with spontaneous melanoma of the orofacial region which was treated by a synthetic inhibitor of cyclin-dependent kinases, i.e…”
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Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells by Priwitzerova, Monika, Pospisilova, Dagmar, Prchal, Josef T, Indrak, Karel, Hlobilkova, Alice, Mihal, Vladimir, Ponka, Prem, Divoky, Vladimir

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