Search Results - "Hjelmesaeth, Joran"
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Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis
Published in Computational and structural biotechnology journal (01-01-2023)“…Human liver tissue is composed of heterogeneous mixtures of different cell types and their cellular stoichiometry can provide information on hepatic physiology…”
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Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL)
Published in BMJ open (01-05-2018)“…IntroductionRoux-en-Y gastric bypass (GBP) is associated with changes in cardiometabolic risk factors and bioavailability of drugs, but whether these changes…”
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Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity
Published in Clinical and translational science (01-11-2022)“…Previous studies have not accounted for the close link between type 2 diabetes mellitus (T2DM) and obesity when investigating the impact of T2DM on cytochrome…”
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Effect of Implementing Routine Early Invasive Strategy on One-Year Mortality in Patients With Acute Myocardial Infarction
Published in The American journal of cardiology (2010)“…The aim of the present study was to investigate whether the implementation of an early invasive strategy for unselected patients with acute myocardial…”
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Short‐ and long‐term effects of body weight loss following calorie restriction and gastric bypass on CYP3A‐activity – a non‐randomized three‐armed controlled trial
Published in Clinical and translational science (01-01-2022)“…It remains uncertain whether pharmacokinetic changes following Roux‐en‐Y gastric bypass (RYGB) can be attributed to surgery‐induced gastrointestinal…”
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New-onset posttransplantation diabetes mellitus: insulin resistance or insulinopenia? Impact of immunosuppressive drugs, cytomegalovirus and hepatitis C virus infection
Published in Current diabetes reviews (01-01-2005)“…Restoration of renal function may ameliorate uremia induced insulin resistance. Therefore it seems a paradox that new-onset posttransplantation diabetes…”
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The effect of tobacco smoking and treatment strategy on the one-year mortality of patients with acute non-ST-segment elevation myocardial infarction
Published in BMC cardiovascular disorders (15-12-2010)“…The aim of the present study was to investigate whether a previously shown survival benefit resulting from routine early invasive management of unselected…”
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Effects of Rapid Versus Gradual Weight Loss on 1-Year Total Body Weight Loss – An RCT
Published in Obesity (Silver Spring, Md.) (01-11-2022)“…Background: Whether rapid or gradual weight loss (RWL/GWL) differently affects long term weight maintenance has been highly debated. We hypothesized that RWL…”
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Comparison of the effect of Roux‐en‐Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes: A systematic review and meta‐analysis of randomized controlled trials
Published in Obesity reviews (01-06-2020)“…Summary Bariatric surgery is an effective treatment option for patients with type 2 diabetes mellitus (T2DM) and obesity. This study aims to compare the…”
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Changes in Dietary Intake and Eating Behavior after Sleeve Gastrectomy Versus Gastric Bypass- an RCT
Published in Obesity (Silver Spring, Md.) (01-11-2022)“…Background: A healthy diet after bariatric surgery is important for preventing weight regain, cardiovascular disease and nutrient deficiencies. Few studies…”
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Long-Term Patient Reported Outcomes After Sleeve Gastrectomy Versus Gastric Bypass Oseberg: An RCT
Published in Obesity (Silver Spring, Md.) (01-11-2022)“…Background: Few RCTs have compared long-term patient reported outcomes (PROs) after sleeve gastrectomy (SG) versus Roux-en-Y gas-tric bypass (RYGB). Methods:…”
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Gastrointestinal Hormones and [beta]-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial
Published in The journal of clinical endocrinology and metabolism (01-02-2022)“…Context: Whether Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) differentially affect postprandial gastrointestinal hormones and [beta]-cell…”
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Association of Bariatric Surgery vs Medical Obesity Treatment With Long-term Medical Complications and Obesity-Related Comorbidities
Published in JAMA : the journal of the American Medical Association (16-01-2018)“…IMPORTANCE: The association of bariatric surgery and specialized medical obesity treatment with beneficial and detrimental outcomes remains uncertain…”
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The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review
Published in Obesity reviews (01-09-2019)“…Summary Anatomical changes in the gastrointestinal tract and subsequent weight loss may influence drug disposition and thus drug dosing following bariatric…”
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Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
Published in Clinical pharmacology and therapeutics (01-05-2022)“…Mathematical models, such as physiologically‐based pharmacokinetic models, are used to predict, for example, drug disposition and toxicity. However,…”
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Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity—A Randomized Controlled Trial
Published in Obesity (Silver Spring, Md.) (01-02-2021)“…Objective This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure. Methods This was a…”
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Human body weight, nutrients, and foods: a scoping review
Published in Food & nutrition research (22-08-2022)“…BackgroundThe aim of this article (scoping review) is to elucidate the current knowledge for the potential role of body weight for setting and updating Dietary…”
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Bone Mineral Density and Turnover After Sleeve Gastrectomy and Gastric Bypass: A Randomized Controlled Trial (Oseberg)
Published in The journal of clinical endocrinology and metabolism (01-02-2021)“…Abstract Context Bariatric surgery, particularly Roux-en-Y gastric bypass (RYGB), is associated with an increased risk of osteoporotic fractures. It is unknown…”
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