Search Results - "Hjalt, Tord"

Fate Maps of Neural Crest and Mesoderm in the Mammalian Eye by Gage, Philip J, Rhoades, William, Prucka, Sandra K, Hjalt, Tord

“…Structures derived from periocular mesenchyme arise by complex interactions between neural crest and mesoderm. Defects in development or function of structures…”
Get full text

Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis by Roybon, Laurent, Hjalt, Tord, Stott, Simon, Guillemot, Francois, Li, Jia-Yi, Brundin, Patrik

“…The specification and differentiation of dentate gyrus granule neurons in the hippocampus require temporally and spatially coordinated actions of both…”
Get full text

Current molecular understanding of Axenfeld-Rieger syndrome by Hjalt, Tord A, Semina, Elena V

“…Axenfeld-Rieger syndrome (ARS) is a rare autosomal dominant inherited disorder affecting the development of the eyes, teeth and abdomen. The syndrome is…”
Get more information

PITX Genes Are Required for Cell Survival and Lhx3 Activation by Charles, Michael A, Suh, Hoonkyo, Hjalt, Tord A, Drouin, Jacques, Camper, Sally A, Gage, Philip J

“…The PITX family of transcription factors regulate the development of many organs. Pitx1 mutants have a mild pituitary phenotype, but Pitx2 is necessary for the…”
Get full text

Identification of novel spinal cholinergic genetic subtypes disclose Chodl and Pitx2 as markers for fast motor neurons and partition cells by Enjin, Anders, Rabe, Nadine, Nakanishi, Stan T., Vallstedt, Anna, Gezelius, Henrik, Memic, Fatima, Lind, Magnus, Hjalt, Tord, Tourtellotte, Warren G., Bruder, Carl, Eichele, Gregor, Whelan, Patrick J., Kullander, Klas

“…Spinal cholinergic neurons are critical for motor function in both the autonomic and somatic nervous systems and are affected in spinal cord injury and in…”
Get full text

An Altered Phenotype in a Conditional Knockout of Pitx2 in Extraocular Muscle by Zhou, Yuefang, Cheng, Georgiana, Dieter, Lisa, Hjalt, Tord A, Andrade, Francisco H, Stahl, John S, Kaminski, Henry J

“…To determine the temporal and spatial expression of Pitx2, a bicoid-like homeobox transcription factor, during postnatal development of mouse extraocular…”
Get full text

Pituitary Homeobox 2 Regulates Adrenal4 Binding Protein/Steroidogenic Factor-1 Gene Transcription in the Pituitary Gonadotrope through Interaction with the Intronic Enhancer by Shima, Yuichi, Zubair, Mohamad, Komatsu, Tomoko, Oka, Sanae, Yokoyama, Chikako, Tachibana, Taro, Hjalt, Tord A, Drouin, Jacques, Morohashi, Ken-ichirou

“…Ad4BP/SF-1 [adrenal4 binding protein/steroidogenic factor-1 (NR5A1)] is a factor important for animal reproduction and endocrine regulation, and its expression…”
Get full text

Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): generation by alternative translation initiation and mRNA splicing by Lamba, Pankaj, Hjalt, Tord A, Bernard, Daniel J

“…Members of the Paired-like homeodomain transcription factor (PITX) gene family, particularly PITX1 and PITX2, play important roles in normal development and in…”
Get full text

Novel expression and transcriptional regulation of FoxJ1 during oro-facial morphogenesis by Venugopalan, Shankar R., Amen, Melanie A., Wang, Jianbo, Wong, Leeyean, Cavender, Adriana C., D'Souza, Rena N., Akerlund, Mikael, Brody, Steve L., Hjalt, Tord A., Amendt, Brad A.

“…Axenfeld–Rieger syndrome (ARS) patients with PITX2 point mutations exhibit a wide range of clinical features including mild craniofacial dysmorphism and dental…”
Get full text

PITX2 Gain-of-Function in Rieger Syndrome Eye Model by Holmberg, Johan, Liu, Chia-Yang, Hjalt, Tord A.

“…The human autosomal-dominant disorder Axenfeld-Rieger syndrome presents with defects in development of the eyes, teeth, and umbilicus. The eye manifests with…”
Get full text

Differential Regulation of Gene Expression by PITX2 Isoforms by Cox, Carol J., Espinoza, Herbert M., McWilliams, Bryan, Chappell, Kimberly, Morton, Lisa, Hjalt, Tord A., Semina, Elena V., Amendt, Brad A.

“…Three major PITX2 isoforms are differentially expressed in human, mice, zebrafish, chick, and frog tissues. To demonstrate differential regulation of gene…”
Get full text

PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5 by Ganga, Mrudula, Espinoza, Herbert M, Cox, Carol J, Morton, Lisa, Hjalt, Tord A, Lee, Youngsook, Amendt, Brad A

“…PITX2 and Nkx2.5 are two of the earliest known transcriptional markers of vertebrate heart development. Pitx2-/- mice present with severe cardiac malformations…”
Get full text

A simple method for large-scale generation of dopamine neurons from human embryonic stem cells by Morizane, Asuka, Darsalia, Vladimer, Guloglu, M. Oktar, Hjalt, Tord, Carta, Manolo, Li, Jia-Yi, Brundin, Patrik

“…Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are potentially valuable in drug screening and as a possible source of donor tissue for…”
Get full text

PITX2 gain-of-function induced defects in mouse forelimb development by Holmberg, Johan, Ingner, Gorel, Johansson, Curt, Leander, Peter, Hjalt, Tord A

“…Limb development and patterning originate from a complex interplay between the skeletal elements, tendons, and muscles of the limb. One of the genes involved…”
Get full text

Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells by Ittner, Lars M, Wurdak, Heiko, Schwerdtfeger, Kerstin, Kunz, Thomas, Ille, Fabian, Leveen, Per, Hjalt, Tord A, Suter, Ueli, Karlsson, Stefan, Hafezi, Farhad, Born, Walter, Sommer, Lukas

“…Abstract Background Development of the eye depends partly on the periocular mesenchyme derived from the neural crest (NC), but the fate of NC cells in…”
Get full text

Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis by Askmyr, Maria, Holmberg, Johan, Flores, Carmen, Ehinger, Mats, Hjalt, Tord, Richter, Johan

“…Objective Infantile malignant osteopetrosis is a fatal disease caused by lack of functional osteoclasts. In most of patients, TCIRG1 , encoding a subunit of a…”
Get full text

PITX2 Regulates Procollagen Lysyl Hydroxylase (PLOD) Gene Expression: Implications for the Pathology of Rieger Syndrome by Hjalt, Tord A., Amendt, Brad A., Murray, Jeffrey C.

“…The Rieger syndrome is an autosomal dominant disease characterized by ocular, craniofacial, and umbilical defects. Patients have mutations in PITX2, a…”
Get full text

Bulged-out nucleotides in an antisense RNA are required for rapid target RNA binding in vitro and inhibition in vivo by Hjalt, Tord Å. H., Gerhart, E., Wagner, H.

“…Naturally occurring antisense RNAs in prokaryotes are generally short, highly structured and untranslated. Stem-loops are always present, and loop regions…”
Get full text

Expression of laminin α1, α5 and β2 chains during embryogenesis of the kidney and vasculature by Durbeej, Madeleine, Fecker, Lothar, Hjalt, Tord, Zhang, Hong-Yan, Salmivirta, Kátriina, Klein, Gerd, Timpl, Rupert, Sorokin, Lydia, Ebendal, Ted, Ekblom, Peter, Ekblom, Marja

“…Laminins, found predominantly in basement membranes, are large glycoproteins consisting of different subsets of α, β and γ chain subunits. To resolve…”
Get full text

The Human BARX2 Gene: Genomic Structure, Chromosomal Localization, and Single Nucleotide Polymorphisms by Hjalt, Tord Å., Murray, Jeffrey C.

“…The BARX genes 1 and 2 are Bar class homeobox genes expressed in craniofacial structures during development. In this report, we present the genomic structure,…”
Get full text