Search Results - "Hizuta, Akio"
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Recombinant Adenovirus Expressing Wild-Type p53 Is Antiangiogenic: A Proposed Mechanism for Bystander Effect
Published in Clinical cancer research (01-05-1999)“…Angiogenesis is required for the growth and progression of malignancies. Recent studies have demonstrated that genetic alterations may accompany acquisition of…”
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Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cells
Published in Oncogene (01-04-1999)“…The CD95 (Fas/APO-1) system regulates a number of physiological and pathological processes of cell death. The ligand for CD95 induces apoptosis in sensitive…”
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Altered Tryptophan and Neopterin Metabolism In Cancer Patients
Published in Pteridines (01-02-1998)“…Plasma 5-hydroxytryptamine (serotonin), tryptophan and neopterin levels were measured in patients with depressive cancer cachexia and in healthy controls…”
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Clinical Value of Neopterin In Infectious Complications
Published in Pteridines (01-02-1999)“…Neopterin, a pteridine intermediate metabolite in the biopterine synthetic pathway, is synthesized and secreted by monocyte/macrophages upon stimulation,…”
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Isolation of MHC Class I-Restricted Tumor Antigen Peptide and Its Precursors Associated with Heat Shock Proteins hsp70, hsp90, and gp96
Published in The Journal of immunology (1950) (01-02-1999)“…We have previously demonstrated that vaccination with heat shock proteins hsp70, hsp90, and gp96 elicits specific immunity against the tumor from which the…”
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p53 expression overcomes p21WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells
Published in Oncogene (16-10-1997)Get full text
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Novel combination therapy for human colon cancer with adenovirus‐mediated wild‐type p53 gene transfer and DNA‐damaging chemotherapeutic agent
Published in International journal of cancer (04-11-1997)“…Alteration of the wild‐type (wt) p53gene by mutation, deletion or re‐arrangement is a major factor in the development of human colon cancer. Recent studies…”
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The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers
Published in Journal of cancer research and clinical oncology (1996)“…We previously reported that introduction of the wild-type p53 gene into human cancer cells with deleted p53 enhanced apoptosis induced by chemotherapy…”
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Basic and clinical studies on tazobactam/piperacillin in surgical infections
Published in CHEMOTHERAPY (1994)“…A new combined drug, tazobactam/piperacillin, incorporated at a ratio of 1:4 was evaluated fundamentally and clinically in the field of surgery. The drug was…”
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Appendiceal mucocele with concomitant colonic cancer. Report of two cases
Published in Diseases of the colon & rectum (01-02-1996)“…Mucocele of the appendix is an uncommon disorder, usually found incidentally during ultrasonography or radiographic studies. We report two cases of combined…”
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Clinical study on biapenem in surgical infections
Published in CHEMOTHERAPY (1994)“…A clinical study on biapenem (BIPM), a new carbapenem was performed in 13 infected patients in the field of surgery. There were obtained excellent in 5…”
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Clinical Results of Hyperthermia for Postoperative Recurrences of Rectal Cancer
Published in Nihon Haipāsāmia Gakkai shi (1993)“…In the period from November 1984 until May 1993 hyperthermia was applied to seven patients with local recurrences of rectal cancer. For the heating we used a…”
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Transfer of S-1108 from serum to lung tissue and bile juice
Published in CHEMOTHERAPY (30-06-1993)“…The aim of this study was to determine the transfer of the antibiotic, S-1108, administered orally, from serum to lung tissue and bile juice. In sixteen…”
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Cancer cachexia and depressive states: a neuro-endocrine-immunological disease?
Published in Acta medica Okayama (01-08-1997)“…Plasma 5-hydroxytryptamine (serotonin), tryptophan, neopterin and cortisol levels were measured in patients with depressive cancer cachexia and in healthy…”
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Penile metastasis secondary to cecum carcinoma: a case report
Published in Hepato-gastroenterology (01-09-1998)“…To date, only around 300 cases of metastasis to the penis have been reported and the primary cancer has been generally found in genitourinary structures…”
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p53 expression overcomes p21WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells
Published in Oncogene (16-10-1997)“…The p21WAF1/CIP1 gene, which encodes a cyclin-dependent kinase inhibitor, may be critical for tumor suppressor gene p53-induced cell cycle arrest. The p53 gene…”
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Soluble intercellular adhesion molecule-1 and natural killer cell activity in gastric cancer patients
Published in Research communications in molecular pathology and pharmacology (01-06-1998)“…Intercellular adhesion molecule-1 (ICAM-1), a molecule bound to the cell surface, is a ligand for leukocyte function antigen-1 (LFA-1), and the ICAM-1/LFA-1…”
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Can POSSUM, a scoring system for perioperative surgical risk, predict postoperative clinical course?
Published in Acta medica Okayama (01-12-1998)“…POSSUM, a Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity, is a scoring system which assesses perioperative surgical…”
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Enhancement of experimental metastasis by gamma-interferon in a murine adenocarcinoma
Published in Acta medica Okayama (01-02-1996)“…This study was conducted to examine the effect of gamma-interferon (IFN-gamma) on experimental metastasis formation by murine colon 26 adenocarcinoma in BALB/c…”
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