Search Results - "Hiyama, Eiso"
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Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
Published in Children (Basel) (05-11-2021)“…In the past decade, navigation surgery using fluorescent indocyanine green (ICG) dye for hepatoblastoma (HB) has been developed for the resection of primary or…”
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Single-cell metabolomics by mass spectrometry: Advances, challenges, and future applications
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-11-2019)“…Cellular heterogeneity is a phenomenon that is often observed but poorly understood. Single-cell metabolomics can provide insights into the phenotypical…”
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Live single cell mass spectrometry reveals cancer‐specific metabolic profiles of circulating tumor cells
Published in Cancer science (01-02-2019)“…Recently, there has been increased attention on the analysis of circulating tumor cells (CTCs), also known as liquid biopsy, owing to its potential benefits in…”
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4
Genetic and epigenetic basis of hepatoblastoma diversity
Published in Nature communications (20-09-2021)“…Hepatoblastoma (HB) is the most common pediatric liver malignancy; however, hereditary predisposition and acquired molecular aberrations related to HB…”
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Single-cell DNA and RNA sequencing of circulating tumor cells
Published in Scientific reports (24-11-2021)“…Single-cell sequencing of circulating tumor cells can precisely represent tumor heterogeneity and provide useful information for cancer treatment and research…”
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Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration
Published in The lancet oncology (01-01-2017)“…Summary Background Comparative assessment of treatment results in paediatric hepatoblastoma trials has been hampered by small patient numbers and the use of…”
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Cancer in adolescents and young adults in Japan: epidemiology and cancer strategy
Published in International journal of clinical oncology (01-01-2022)“…According to national cancer registry data in Japan, approximately 20,000 adolescents and young adults (AYAs, age 15–39 years) are newly diagnosed with cancer…”
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The Children's Hepatic tumors International Collaboration (CHIC): Novel global rare tumor database yields new prognostic factors in hepatoblastoma and becomes a research model
Published in European journal of cancer (1990) (01-01-2016)“…Contemporary state-of-the-art management of cancer is increasingly defined by individualized treatment strategies. For very rare tumors, like hepatoblastoma,…”
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Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium
Published in Modern pathology (01-03-2014)“…Liver tumors are rare in children, and their diagnoses may be challenging particularly because of the lack of a current consensus classification system…”
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TERT promotor region rearrangements analyzed in high-risk neuroblastomas by FISH method and whole genome sequencing
Published in International journal of clinical oncology (01-12-2020)“…Background Unfavorable neuroblastomas (NBLs) achieve telomere stabilization via telomerase activation through MYCN amplification, TERT promoter region ( TERT…”
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Single‐cell next‐generation sequencing of circulating tumor cells in patients with neuroblastoma
Published in Cancer science (01-04-2023)“…Circulating tumor cells (CTCs) derived from any tumor tissue could contribute to metastasis and resistance to cancer treatments. In this study, we performed…”
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Single-Cell Screening of Tamoxifen Abundance and Effect Using Mass Spectrometry and Raman-Spectroscopy
Published in Analytical chemistry (Washington) (19-02-2019)“…Monitoring drug uptake, its metabolism, and response on the single-cell level is invaluable for sustaining drug discovery efforts. In this study, we show the…”
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Laparoscopic approach for abdominal neuroblastoma in Japan: results from nationwide multicenter survey
Published in Surgical endoscopy (01-05-2022)“…Background Some neuroblastoma (NB) cases are suitable for minimally invasive surgery (MIS), but indication and technical issue are unclear. We assessed the…”
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Current therapeutic strategies for childhood hepatic malignant tumors
Published in International journal of clinical oncology (01-12-2013)“…The two main malignant hepatic tumors in children are hepatoblastomas (HBLs) and hepatocellular carcinomas (HCCs). The past two decades have brought…”
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15
Optic tract edema in craniopharyngioma as a predictor of BRAFV600E mutation presence
Published in Japanese journal of clinical oncology (29-04-2023)“…Abstract Objective the advent of BRAF inhibitors for preoperative treatment of craniopharyngioma has necessitated the identification of BRAFV600E status…”
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Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells
Published in PloS one (19-07-2019)“…Although the biological systems in the human body are affected by the earth's gravity, information about the underlying molecular mechanisms is limited. For…”
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Direct Lipido-Metabolomics of Single Floating Cells for Analysis of Circulating Tumor Cells by Live Single-cell Mass Spectrometry
Published in Analytical Sciences (2015)“…Direct trapping of a single floating cell, i.e. a white blood cell from a drop of blood, within a nanospray tip was followed by super-sonication after the…”
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Outcome and Late Complications of Hepatoblastomas Treated Using the Japanese Study Group for Pediatric Liver Tumor 2 Protocol
Published in Journal of clinical oncology (01-08-2020)“…We report here the outcomes and late effects of the Japanese Study Group for Pediatric Liver Tumors (JPLT)-2 protocol, on the basis of…”
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Clinical Implications of Pre- and Postoperative Circulating Tumor DNA in Patients with Resected Pancreatic Ductal Adenocarcinoma
Published in Annals of surgical oncology (01-06-2021)“…Background The clinical implications of pre- and postoperative KRAS -mutated circulating tumor DNA (ctDNA) present in patients with pancreatic ductal…”
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Hypermethylation of CSF3R is a novel cisplatin resistance marker and predictor of response to postoperative chemotherapy in hepatoblastoma
Published in Hepatology research (01-05-2020)“…Aim Most hepatoblastoma patients undergo pre/postoperative cisplatin treatment. Approximately 20% patients are cisplatin resistant, and show poor prognosis and…”
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