Search Results - "Hiura, Yumiko"

Plasma miR-208 as a Biomarker of Myocardial Injury by Ji, Xu, Takahashi, Rie, Hiura, Yumiko, Hirokawa, Go, Fukushima, Yasue, Iwai, Naoharu

“…MicroRNAs (miRNAs) are endogenous small RNAs of 21-25 nucleotides that can pair with sites in 3' untranslated regions in mRNAs of protein-coding genes to…”
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Inhalation Exposure to Carbon Black Induces Inflammatory Response in Rats by Niwa, Yasuharu, Hiura, Yumiko, Sawamura, Hiromi, Iwai, Naoharu

“…Background A link between exposure to fine particulate matter and cardiovascular events has been established. Inhaled nanoparticles are thought to pass through…”
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A Genome-Wide Association Study of Hypertension-Related Phenotypes in a Japanese Population by Hiura, Yumiko, Tabara, Yasuharu, Kokubo, Yoshihiro, Okamura, Tomonori, Miki, Tetsuro, Tomoike, Hitonobu, Iwai, Naoharu

“…Background: Large-scale genome-wide association studies (GWAS) have been successful in identifying genes that contribute to common diseases and phenotypes. A…”
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Nano-Sized Carbon Black Exposure Exacerbates Atherosclerosis in LDL-Receptor Knockout Mice by Niwa, Yasuharu, Hiura, Yumiko, Murayama, Toshinori, Yokode, Masayuki, Iwai, Naoharu

“…Background Associations between exposure to particulate matter and susceptibility to cardiovascular events have been reported. Although the underlying…”
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Validation of the Association of Genetic Variants on Chromosome 9p21 and 1q41 With Myocardial Infarction in a Japanese Population by Hiura, Yumiko, Fukushima, Yasue, Yuno, Miyuki, Sawamura, Hiromi, Kokubo, Yoshihiro, Okamura, Tomonori, Tomoike, Hitonobu, Goto, Yoichi, Nonogi, Hiroshi, Takahashi, Rie, Iwai, Naoharu

“…Background Recent large-scale genome-wide association studies have identified several loci associated with the risk of coronary artery disease (CAD). The aim…”
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Identification of Genetic Markers Associated With High-Density Lipoprotein-Cholesterol by Genome-Wide Screening in a Japanese Population: The Suita Study by Hiura, Yumiko, Shen, Chun-Shen, Kokubo, Yoshihiro, Okamura, Tomonori, Morisaki, Takayuki, Tomoike, Hitonobu, Yoshida, Teruhiko, Sakamoto, Hiromi, Goto, Yoichi, Nonogi, Hiroshi, Iwai, Naoharu

“…Background: Recent genome-wide association studies (GWAS) have identified genes or loci affecting lipid levels. Given the difference in allele frequencies and…”
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Association of the Functional Variant in the 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Gene With Low-Density Lipoprotein-Cholesterol in Japanese by Hiura, Yumiko, Tabara, Yasuharu, Kokubo, Yoshihiro, Okamura, Tomonori, Goto, Yoichi, Nonogi, Hiroshi, Miki, Tetsuro, Tomoike, Hitonobu, Iwai, Naoharu

“…Background: The association between single nucleotide polymorphisms (SNPs) at 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and low-density…”
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Effects of the Y Chromosome on Cardiovascular Risk Factors in Japanese Men by Hiura, Yumiko, Fukushima, Yasue, Kokubo, Yoshihiro, Okamura, Tomonori, Goto, Yoichi, Nonogi, Hiroshi, Takahashi, Rie, Iwai, Naoharu

“…Excess cardiovascular risk in men compared with women has been suggested to be partly explained by effects of the Y chromosome. However, inconsistent results…”
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Exclusion of the catechol-o-methyltransferase gene from genes contributing to salt-sensitive hypertension in dahl salt-sensitive rats by Kajimoto, Kazuaki, Hiura, Yumiko, Sumiya, Toshiki, Yasui, Naomi, Okuda, Tomohiko, Iwai, Naoharu

“…Catechol-O-methyltransferase (COMT) is an enzyme that inactivates catecholamines. Several studies have suggested that this enzyme may play a role in blood…”
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Assessment of Mitochondrial DNA Polymorphisms in Salt-Sensitive Hypertension in Dahl Salt-Sensitive Rats by Chen, Chu-Shih, Hiura, Yumiko, Shen, Chun-Shen, Iwai, Naoharu

“…The Dahl salt-sensitive (DS) rat is the most prevalently used animal model of salt-sensitive hypertension. The purpose of the present study was to test the…”
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P2X(7) receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats by Ji, Xu, Naito, Yukiko, Hirokawa, Go, Weng, Huachun, Hiura, Yumiko, Takahashi, Rie, Iwai, Naoharu

“…The P2X(7) receptor is a ligand-gated ion channel activated by extracellular ATP, and a common genetic variation in the P2X(7) gene significantly affects blood…”
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Common Variants in the ATP2B1 Gene Are Associated With Susceptibility to Hypertension: The Japanese Millennium Genome Project by Tabara, Yasuharu, Kohara, Katsuhiko, Kita, Yoshikuni, Hirawa, Nobuhito, Katsuya, Tomohiro, Ohkubo, Takayoshi, Hiura, Yumiko, Tajima, Atsushi, Morisaki, Takayuki, Miyata, Toshiyuki, Nakayama, Tomohiro, Takashima, Naoyuki, Nakura, Jun, Kawamoto, Ryuichi, Takahashi, Norio, Hata, Akira, Soma, Masayoshi, Imai, Yutaka, Kokubo, Yoshihiro, Okamura, Tomonori, Tomoike, Hitonobu, Iwai, Naoharu, Ogihara, Toshio, Inoue, Itsuro, Tokunaga, Katsushi, Johnson, Toby, Caulfield, Mark, Munroe, Patricia, Umemura, Satoshi, Ueshima, Hirotsugu, Miki, Tetsuro

“…Hypertension is one of the most common complex genetic disorders. We have described previously 38 single nucleotide polymorphisms (SNPs) with suggestive…”
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Targeted deletion of miR-182, an abundant retinal microRNA by Jin, Zi-Bing, Hirokawa, Go, Gui, Le, Takahashi, Rie, Osakada, Fumitaka, Hiura, Yumiko, Takahashi, Masayo, Yasuhara, Osamu, Iwai, Naoharu

“…MicroRNA-182 (miR-182) is expressed abundantly in the mammalian retina and is therefore thought to perform important roles for the retinal development and the…”
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Association of four genetic loci with uric acid levels and reduced renal function: the J-SHIPP Suita study by Tabara, Yasuharu, Kohara, Katsuhiko, Kawamoto, Ryuichi, Hiura, Yumiko, Nishimura, Kunihiro, Morisaki, Takayuki, Kokubo, Yoshihiro, Okamura, Tomonori, Tomoike, Hitonobu, Iwai, Naoharu, Miki, Tetsuro

“…Recent genome-wide association studies have identified several genetic variants as susceptibility loci for serum uric acid (UA) levels. We also identified a…”
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P2X7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats by Ji, Xu, Naito, Yukiko, Hirokawa, Go, Weng, Huachun, Hiura, Yumiko, Takahashi, Rie, Iwai, Naoharu

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Identification of Genetic Markers Associated With High-Density Lipoprotein-Cholesterol by Genome-Wide Screening in a Japanese PopulationThe Suita Study by Hiura, Yumiko, Shen, Chun-Shen, Kokubo, Yoshihiro, Okamura, Tomonori, Morisaki, Takayuki, Tomoike, Hitonobu, Yoshida, Teruhiko, Sakamoto, Hiromi, Goto, Yoichi, Nonogi, Hiroshi, Iwai, Naoharu

“…Background: Recent genome-wide association studies (GWAS) have identified genes or loci affecting lipid levels. Given the difference in allele frequencies and…”
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Hunting for genes for hypertension: the Millennium Genome Project for Hypertension by Tabara, Yasuharu, Kohara, Katsuhiko, Miki, Tetsuro

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For the patient. Hypertriglyceridemic waist as a screening tool for CVD risk in Australian indigenous women by Hiura, Yumiko, Acklin, Fay, Newman, Jennifer, Steinbeck, Kate, Caterson, Ian D, Mahajan, Deepika, Brock, Kaye, Bermingham, Margaret A

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Hypertriglyceridemic waist as a screening tool for CVD risk in indigenous Australian women by Hiura, Yumiko, Acklin, Fay, Newman, Jennifer, Steinbeck, Kate, Caterson, Ian D, Mahajan, Deepika, Brock, Kaye, Bermingham, Margaret A

“…Research has demonstrated that the simultaneous determination of waist circumference and fasting plasma triglyceride (TG) concentrations can identify men…”
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