Search Results - "Hitchcock, L"
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Don't ignore perimenopause
Published in Canadian Medical Association journal (CMAJ) (31-07-2023)Get full text
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Epigenetic Regulation of miR-17∼92 Contributes to the Pathogenesis of Pulmonary Fibrosis
Published in American journal of respiratory and critical care medicine (15-02-2013)“…Idiopathic pulmonary fibrosis (IPF) is a disease of progressive lung fibrosis with a high mortality rate. In organ repair and remodeling, epigenetic events are…”
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Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial
Published in Scientific reports (05-06-2023)“…This study tested progesterone for perimenopausal hot flush ± night sweat (vasomotor symptom, VMS) treatment. It was a double-blind, randomized trial of 300 mg…”
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Daily associations with cannabis use and sleep quality in anxious cannabis users
Published in Behavioral sleep medicine (03-03-2024)“…Cannabis is increasingly used to self-treat anxiety and related sleep problems, without clear evidence of either supporting or refuting its anxiolytic or sleep…”
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Transcriptomic response of the red tide dinoflagellate, Karenia brevis, to nitrogen and phosphorus depletion and addition
Published in BMC genomics (05-07-2011)“…The role of coastal nutrient sources in the persistence of Karenia brevis red tides in coastal waters of Florida is a contentious issue that warrants…”
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Physical activity, body mass index and bone mineral density—associations in a prospective population-based cohort of women and men: The Canadian Multicentre Osteoporosis Study (CaMos)
Published in Bone (New York, N.Y.) (01-01-2012)“…Abstract Background Physical activity (PA) is an important modifiable risk factor for both bone mineral density (BMD) and body mass index (BMI). However, BMI…”
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Survival Advantage Following TAG-72 Antigen-Directed Cancer Surgery in Patients With Colorectal Carcinoma: Proposed Mechanisms of Action
Published in Frontiers in oncology (07-12-2021)“…Patients with colorectal carcinoma (CRC) continue to have variable clinical outcomes despite undergoing the same surgical procedure with curative intent and…”
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Progesterone therapy, endothelial function and cardiovascular risk factors: a 3-month randomized, placebo-controlled trial in healthy early postmenopausal women
Published in PloS one (21-01-2014)“…Progesterone is effective treatment for hot flushes/night sweats. The cardiovascular effects of progesterone therapy are unknown but evidence suggests that…”
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Proteomic Signatures of Thymomas
Published in PloS one (10-11-2016)“…Based on the histological features and outcome, the current WHO classification separates thymomas into A, AB, B1, B2 and B3 subtypes. It is hypothesized that…”
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A Concept for Preoperative and Intraoperative Molecular Imaging and Detection for Assessing Extent of Disease of Solid Tumors
Published in Oncology reviews (25-07-2024)“…The authors propose a concept of "systems engineering," the approach to assessing the extent of diseased tissue (EODT) in solid tumors. We modeled the proof of…”
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Enantiomeric Identification of Pregabalin by GC‐MS via Methylation and S‐TPC Chiral Derivatization
Published in Journal of forensic sciences (01-03-2019)“…Pregabalin is a Schedule V controlled substance which is defined as the (S) enantiomer of 3‐(aminomethyl)‐5‐methylhexanoic acid. It is used legitimately to…”
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A Wearable Goggle Navigation System for Dual-Mode Optical and Ultrasound Localization of Suspicious Lesions: Validation Studies Using Tissue-Simulating Phantoms and an Ex Vivo Human Breast Tissue Model
Published in PloS one (01-07-2016)“…Surgical resection remains the primary curative treatment for many early-stage cancers, including breast cancer. The development of intraoperative guidance…”
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Progesterone therapy increases free thyroxine levels-data from a randomized placebo-controlled 12-week hot flush trial
Published in Clinical endocrinology (Oxford) (01-08-2013)“…Summary Objective Thyroid hormones and progesterone both influence core temperature, metabolism and are crucial during pregnancy. Our objective was to discover…”
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An Obesity Paradox: An Inverse Correlation between Body Mass Index and Atherosclerosis of the Aorta
Published in Cardiovascular pathology (01-11-2016)“…Abstract Background and aims Morbid obesity generally has been associated with higher morbidity and mortality for a variety of diseases. However, a number of…”
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A Subset of Membrane-Associated Proteins Is Ubiquitinated in Response to Mutations in the Endoplasmic Reticulum Degradation Machinery
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2003)“…Ubiquitination of membrane-associated proteins can direct their proteasome-mediated degradation or activation at the endoplasmic reticulum (ER), as well as…”
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Effects of laser excitation wavelength and optical mode on Raman spectra of human fresh colon, pancreas, and prostate tissues
Published in Journal of Raman spectroscopy (01-09-2014)“…Early cancer detection is the central and most important factor for allowing successful treatment and resultant positive long‐term patient outcomes. Recently,…”
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Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials
Published in BMJ (Online) (01-04-2020)“…AbstractObjectiveTo determine the relative effectiveness of dietary macronutrient patterns and popular named diet programmes for weight loss and cardiovascular…”
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Fusion Positron Emission/Computed Tomography Underestimates the Presence of Hilar Nodal Metastases in Patients With Resected Non-Small Cell Lung Cancer
Published in The Annals of thoracic surgery (01-05-2012)“…Background The 5-year survival for patients with resected stage II (N1) non-small cell lung cancer ranges from 40% to 55%. No data exist addressing the benefit…”
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Temperature and Host Species Affect Nuptial Gift Size in a Seed-Feeding Beetle
Published in Functional ecology (01-12-2006)“…1. In many insects species, males contribute large nutritional gifts to females during mating, generally as seminal fluids (ejaculates) or spermatophores…”
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