Search Results - "Hishimoto, A"

Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders by Hiroi, N, Takahashi, T, Hishimoto, A, Izumi, T, Boku, S, Hiramoto, T

“…Recently discovered genome-wide rare copy number variants (CNVs) have unprecedented levels of statistical association with many developmental neuropsychiatric…”
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Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands by Liu, Q.‐R., Pan, C.‐H., Hishimoto, A., Li, C.‐Y., Xi, Z.‐X., Llorente‐Berzal, A., Viveros, M.‐P., Ishiguro, H., Arinami, T., Onaivi, E. S., Uhl, G. R.

“…Cannabinoids, endocannabinoids and marijuana activate two well‐characterized cannabinoid receptors (CB‐Rs), CB1‐Rs and CB2‐Rs. The expression of CB1‐Rs in the…”
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Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis by Boku, S, Izumi, T, Abe, S, Takahashi, T, Nishi, A, Nomaru, H, Naka, Y, Kang, G, Nagashima, M, Hishimoto, A, Enomoto, S, Duran-Torres, G, Tanigaki, K, Zhang, J, Ye, K, Kato, S, Männistö, P T, Kobayashi, K, Hiroi, N

“…Working memory capacity, a critical component of executive function, expands developmentally from childhood through adulthood. Anomalies in this developmental…”
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Plasma MMP-9 Levels as the Future Risk of Conversion to Dementia in ApoE4-Positive MCI Patients: Investigation Based on the Alzheimer’s Disease Neuroimaging Initiative Database by Abe, K., Chiba, Yuhei, Ide, K., Yoshimi, A., Asami, T., Suda, A., Odawara, T., Hishimoto, A.

“…Background Matrix metalloproteinase 9 (MMP-9) has been reported to be correlated with declines in hippocampal volume and cognitive function in ApoE4-positive…”
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A functional polymorphism of the µ-opioid receptor gene is associated with completed suicides by Hishimoto, A., Cui, H., Mouri, K., Nushida, H., Ueno, Y., Maeda, K., Shirakawa, O.

“…A recent linkage study suggested that a putative locus for suicidal behavior independent of psychiatric disease phenotypes lies at 5′ upstream of the µ-opioid…”
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Alcohol and aldehyde dehydrogenase polymorphisms and risk for suicide: a preliminary observation in the Japanese male population by Hishimoto, A., Fukutake, M., Mouri, K., Nagasaki, Y., Asano, M., Ueno, Y., Nishiguchi, N., Shirakawa, O.

“…Epidemiological studies have shown that excessive alcohol consumption is a potent risk factor to develop suicidal behavior. Genetic factors for suicidal…”
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P03-293 - Alcohol and aldehyde dehydrogenase polymorphisms and risk for suicide by Hishimoto, A, Mouri, K, Fukutake, M, Shiroiwa, K

“…Excessive alcohol consumption plays a crucial role in the pathogenesis of suicide. Because certain functional alleles of alcohol dehydrogenase ( ADH1B ) and…”
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Association between a functional polymorphism in the renin-angiotensin system and completed suicide by Hishimoto, A, Shirakawa, O, Nishiguchi, N, Hashimoto, T, Yanagi, M, Nushida, H, Ueno, Y, Maeda, K

“…Suicide has been suggested to involve disturbances in the stress response system and to be related to genetics. The renin-angiotensin system (RAS) has been…”
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P03-446 - Association of FKBP5 gene haplotypes with completed suicide in the Japanese population by Hishimoto, A, Sasada, T, Fukutake, M, Shiroiwa, K, Supriyanto, I, Shirakawa, O

“…Background The hypothalamus-pituitary-adrenal (HPA) axis is known to have a role in suicidal behaviors in patients with affective disorders. However, the…”
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Alterations in DNA methylation rates of brain-derived neurotrophic factor in patients with schizophrenia by Nojima, S., Fuchikami, M., Kataoka, T., Araki, M., Omura, J., Miyagi, T., Okamoto, Y., Hishimoto, A., Morinobu, S.

“…Schizophrenia (SZ) is one of the most disabling mental illness and the elucidation of diagnostic and therapeutic biomarkers are required. Recent studies…”
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Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia by Tanifuji, Takaki, Okazaki, Satoshi, Otsuka, Ikuo, Horai, Tadasu, Shinko, Yutaka, Kim, Saehyeon, Sora, Ichiro, Hishimoto, Akitoyo

“…Monoamine oxidase-A (MAO-A) decomposes dopamine and serotonin, and decreased MAO-A expression increases monoamine levels and is related to the pathophysiology…”
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Investigation of chromosome Y loss in men with schizophrenia by Hirata, Takashi, Hishimoto, Akitoyo, Otsuka, Ikuo, Okazaki, Satoshi, Boku, Shuken, Kimura, Atsushi, Horai, Tadasu, Sora, Ichiro

“…Life expectancy is 10-20 years lower in patients with schizophrenia than in the general population. In addition, men with schizophrenia have an earlier age at…”
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Rare compound heterozygous missense SPATA7 variations and risk of schizophrenia; whole-exome sequencing in a consanguineous family with affected siblings, follow-up sequencing and a case-control study by Igeta, Hirofumi, Watanabe, Yuichiro, Morikawa, Ryo, Ikeda, Masashi, Otsuka, Ikuo, Hoya, Satoshi, Koizumi, Masataka, Egawa, Jun, Hishimoto, Akitoyo, Iwata, Nakao, Someya, Toshiyuki

“…Whole-exome sequencing (WES) of multiplex families is a promising strategy for identifying causative variations for common diseases. To identify rare recessive…”
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Association analysis of the Cadherin13 gene with schizophrenia in the Japanese population by Otsuka, Ikuo, Watanabe, Yuichiro, Hishimoto, Akitoyo, Boku, Shuken, Mouri, Kentaro, Shiroiwa, Kyoichi, Okazaki, Satoshi, Nunokawa, Ayako, Shirakawa, Osamu, Someya, Toshiyuki, Sora, Ichiro

“…Cadherin13 (CDH13) is a glycosylphosphatidylinositol-anchored cell adhesion molecule that plays a crucial role in morphogenesis and the maintenance of neuronal…”
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A cross-sectional study exploring useful indicators for low bone mineral density in male alcoholic patients by Horai, Tadasu, Hishimoto, Akitoyo, Otsuka, Ikuo, So, Tatsuhiro, Mouri, Kentaro, Shimmyo, Naofumi, Boku, Shuken, Okishio, Noriaki, Sora, Ichiro

“…Alcohol dependence induces low bone mineral density (BMD), predicting osteoporosis, while low and moderate alcohol consumption may even increase BMD. In recent…”
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Association study of MIF promoter polymorphisms with suicide completers in the Japanese population by Shimmyo, Naofumi, Hishimoto, Akitoyo, Otsuka, Ikuo, Okazaki, Satoshi, Boku, Shuken, Mouri, Kentaro, Horai, Tadasu, Takahashi, Motonori, Ueno, Yasuhiro, Shirakawa, Osamu, Sora, Ichiro

“…Numerous studies suggest that inflammation plays a key role in suicidal behavior. Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, has…”
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Association of FKBP5 gene haplotypes with completed suicide in the Japanese population by Hishimoto, A., Sasada, T., Fukutake, M., Shiroiwa, K., Supriyanto, I., Shirakawa, O.

“…Background The hypothalamus-pituitary-adrenal (HPA) axis is known to have a role in suicidal behaviors in patients with affective disorders. However, the…”
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Serotonin transporter regulatory region polymorphism is associated with anorexia nervosa by Matsushita, Sachio, Suzuki, Kenji, Murayama, Masanobu, Nishiguchi, Naoki, Hishimoto, Akitoyo, Takeda, Aya, Shirakawa, Osamu, Higuchi, Susumu

“…Several lines of evidence support possible serotonin transporter (5‐HTT) involvement in modulating eating disorders (ED). The 5‐HTT gene is a good candidate…”
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The mental world of autism spectrum disorder through the experience of psychological interview and examination for a case by Iwamoto, N., Matsui, Y., Tamaoka, A., Honaga, E., Hishimoto, A., Tanaka, K.

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Changes of behavioral problems of children at a children's home in Japan, accompanied by the downsizing by Tanaka, K., Mandai, T., Iwamoto, N., Matsui, Y., Kitayama, S., Honaga, E., Tamaoka, A., Hishimoto, A.

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