Search Results - "Hisatomi, Akitaka"

Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease by Eguchi, Yuichiro, Eguchi, Takahisa, Mizuta, Toshihiko, Ide, Yasushi, Yasutake, Tsutomu, Iwakiri, Ryuichi, Hisatomi, Akitaka, Ozaki, Iwata, Yamamoto, Kyousuke, Kitajima, Yoichiro, Kawaguchi, Yasunori, Kuroki, Shigetaka, Ono, Naofumi

“…Nonalcoholic fatty liver diseases are often associated with obesity, insulin resistance, and excessive visceral fat accumulation. The aims of this study were…”
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Sick day treatment of diabetic patients by Hisatomi, Akitaka

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Hepatitis C virus infection enhances insulin resistance induced by visceral fat accumulation by Eguchi, Yuichiro, Mizuta, Toshihiko, Ishibashi, Eriko, Kitajima, Yoichiro, Oza, Noriko, Nakashita, Shunya, Hara, Megumi, Iwane, Shinji, Takahashi, Hirokazu, Akiyama, Takumi, Ario, Keisuke, Kawaguchi, Yasunori, Yasutake, Tsutomu, Iwakiri, Ryuichi, Ozaki, Iwata, Hisatomi, Akitaka, Eguchi, Takahisa, Ono, Naofumi, Fujimoto, Kazuma

“…Background/Aims: To clarify the impact of visceral obesity on hepatitis C virus (HCV)‐infected patients, we examined the relationship between insulin…”
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Transforming growth factor‐β1‐induced apoptosis is blocked by β1‐integrin‐mediated mitogen‐activated protein kinase activation in human hepatoma cells by Zhang, Hao, Ozaki, Iwata, Mizuta, Toshihiko, Yoshimura, Toru, Matsuhashi, Sachiko, Eguchi, Yuichiro, Yasutake, Tsutomu, Hisatomi, Akitaka, Sakai, Takahiro, Yamamoto, Kyosuke

“…Growth factors and extracellular matrices cooperatively regulate cellular behavior. However, the interactions between transforming growth factor‐β1 (TGF‐β1)…”
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Improved Cardio-Respiratory Fitness Correlates with Changes in the Number and Size of Small Dense LDL: Randomized Controlled Trial with Exercise Training and Dietary Instruction by Kawano, Masayo, Shono, Naoko, Yoshimura, Toru, Yamaguchi, Miyuki, Hirano, Tsutomu, Hisatomi, Akitaka

“…Objective To investigate the correlation between lifestyle improvements, in particular increased cardio-respiratory fitness and changes in the blood lipid…”
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β1‐integrin protects hepatoma cells from chemotherapy induced apoptosis via a mitogen‐activated protein kinase dependent pathway by Zhang, Hao, Ozaki, Iwata, Mizuta, Toshihiko, Matsuhashi, Sachiko, Yoshimura, Tohru, Hisatomi, Akitaka, Tadano, Jutaro, Sakai, Takahiro, Yamamoto, Kyosuke

“…BACKGROUND β1‐integrin modulates cellular phenotype by mediating signals from the extracellular matrix (ECM). Although overexpression of integrin molecules in…”
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High serum leptin is an independent risk factor for non-response patients with low viremia to antiviral treatment in chronic hepatitis C by Eguchi, Yuichiro, Mizuta, Toshihiko, Yasutake, Tsutomu, Hisatomi, Akitaka, Iwakiri, Ryuichi, Ozaki, Iwata, Fujimoto, Kazuma

“…To determine whether body weight and/or serum leptin were independent predictors of response to antiviral treatment in patients with chronic hepatitis C. A…”
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Hepatocyte growth factor induces collagenase (matrix metalloproteinase-1) via the transcription factor Ets-1 in human hepatic stellate cell line by Ozaki, Iwata, Zhao, Gang, Mizuta, Toshihiko, Ogawa, Yoko, Hara, Toshiya, Kajihara, Susumu, Hisatomi, Akitaka, Sakai, Takahiro, Yamamoto, Kyosuke

“…Background/Aims : Although hepatocyte growth factor recently has been shown to decrease hepatic fibrosis in animal models, the molecular mechanisms of this…”
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Bleeding and stenosis caused by reflux esophagitis was not common in emergency endoscopic examinations: a retrospective patient chart review at a single institution in Japan by Yamaguchi, Miyuki, Iwakiri, Ryuichi, Yamaguchi, Kanako, Mizuta, Toshihiko, Shimoda, Ryo, Sakata, Yasuhisa, Hisatomi, Akitaka, Mizuguchi, Masanobu, Sato, Seiji, Miyazaki, Kohji, Fujimoto, Kazuma

“…Background Bleeding and stenosis are serious complications of reflux esophagitis, although few studies have been performed in Japan regarding these…”
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A case of ketoacidosis caused by the breakdown of the infusion syringe during continuous subcutaneous insulin infusion by Izumi, Kenichi, Mori, Hitoe, Kojima, Motoyasu, Takagi, Yusuke, Kawata, Nozomi, Yanagi, Yui, Takagi, Satoko, Nishimura, Hiroko, Ashida, Kenji, Hisatomi, Akitaka, Anzai, Keizo

“…Introduction Continuous subcutaneous insulin injection (CSII) is an effective method for controlling blood glucose. However, complications include cutaneous…”
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Low Blood Flow Estimates in Lower-Leg Arteries Predict Cardiovascular Events in Japanese Patients With Type 2 Diabetes With Normal Ankle-Brachial Indexes by Yoshimura, Toru, Suzuki, Eiji, Egawa, Katsuya, Nishio, Yoshihiko, Maegawa, Hiroshi, Morikawa, Shigehiro, Inubushi, Toshiro, Hisatomi, Akitaka, Fujimoto, Kazuma, Kashiwagi, Atsunori

“…OBJECTIVE:--To examine the association of baseline measures in lower-leg arteries and conventional cardiovascular risk factors with the incidence of…”
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Progress in diagnosis of and therapy for diabetic ketoacidosis by Hisatomi, Akitaka

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The Relationship between Insulin Resistance and Polymorphisms of the Endothelial Nitric Oxide Synthase Gene in Patients with Coronary Artery Disease by Yoshimura, Toru, Hisatomi, Akitaka, Kajihara, Susumu, Yasutake, Tsutomu, Ogawa, Youko, Mizuta, Toshihiko, Ozaki, Iwata, Utsunomiya, Toshinori, Yamamoto, Kyosuke

“…Nitric oxide (NO) regulates endothelial function and is believed to prevent atherogenesis. In endothelial cells, endothelial nitric oxide synthase (eNOS) is…”
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A Splice Mutation in the Human Canalicular Multispecific Organic Anion Transporter Gene Causes Dubin-Johnson Syndrome by Kajihara, Susumu, Hisatomi, Akitaka, Mizuta, Toshihiko, Hara, Toshiya, Ozaki, Iwata, Wada, Ikuko, Yamamoto, Kyosuke

“…The human Dubin Johnson syndrome (DJS) is a rare autosomal recessive disorder characterized by chronic conjugated hyperbilirubinemia and impaired hepatobiliary…”
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Efficacy, Safety, and Tolerability of Oral Semaglutide Versus Placebo Added to Insulin With or Without Metformin in Patients With Type 2 Diabetes: The PIONEER 8 Trial by Zinman, Bernard, Aroda, Vanita R, Buse, John B, Cariou, Bertrand, Harris, Stewart B, Hoff, Søren Tetens, Pedersen, Karen Boje, Tarp-Johansen, Mads Jeppe, Araki, Eiichi

“…To investigate the efficacy, safety, and tolerability of oral semaglutide added to insulin with or without metformin. Patients with type 2 diabetes…”
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Suppression of apoptosis is responsible for increased thickness of intestinal mucosa in streptozotocin-induced diabetic rats by Noda, Takahiro, Iwakiri, Ryuichi, Fujimoto, Kazuma, Yoshida, Toshifumi, Utsumi, Hiroyoshi, Sakata, Hiroyuki, Hisatomi, Akitaka, Aw, Tak Yee

“…Intestinal mucosal growth is a common, but uncharacterized, observation associated with diabetes mellitus. Epithelial homeostasis is balanced by regulation of…”
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Eradication of hepatitis C virus by interferon improves whole-body insulin resistance and hyperinsulinaemia in patients with chronic hepatitis C by Kawaguchi, Yasunori, Mizuta, Toshihiko, Oza, Noriko, Takahashi, Hirokazu, Ario, Keisuke, Yoshimura, Toru, Eguchi, Yuichiro, Ozaki, Iwata, Hisatomi, Akitaka, Fujimoto, Kazuma

“…Background/Aims: To investigate whether eradication of hepatitis C virus (HCV) by interferon (IFN) therapy influences systemic glucose metabolism. Methods:…”
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Whole-Body Insulin Sensitivity Index Is a Highly Specific Predictive Marker for Virological Response to Peginterferon Plus Ribavirin Therapy in Chronic Hepatitis C Patients with Genotype 1b and High Viral Load by Mizuta, Toshihiko, Kawaguchi, Yasunori, Eguchi, Yuichiro, Takahashi, Hirokazu, Ario, Keisuke, Akiyama, Takumi, Oza, Noriko, Otsuka, Taiga, Kuwashiro, Takuya, Yoshimura, Toru, Hisatomi, Akitaka, Ozaki, Iwata

“…Insulin resistance is a candidate predictive factor for virological response to peginterferon plus ribavirin (PEG/RBV) therapy in chronic hepatitis C patients…”
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Higher arterial stiffness, greater peripheral vascular resistance and lower blood flow in lower-leg arteries are associated with long-term hyperglycaemia in type 2 diabetic patients with normal ankle-brachial index by Suzuki, Eiji, Yoshimura, Toru, Omura, Yasushi, Sakaguchi, Masayoshi, Nishio, Yoshihiko, Maegawa, Hiroshi, Hisatomi, Akitaka, Fujimoto, Kazuma, Takeda, Jun, Kashiwagi, Atsunori

“…Background Higher arterial stiffness and greater peripheral vascular resistance reduce blood flow in lower‐leg arteries and contribute to the development of…”
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A case of insulin allergy: the crystalline human insulin may mask its antigenicity by Takatsuki, H, Ishii, H, Yamauchi, T, Nakashima, N, Nagase, S, Hisatomi, A, Umeda, F, Nawata, H

“…We report an unusual case of insulin allergy. A 48-year-old man with non-insulin-dependent diabetes mellitus receiving biosynthetic isophane human insulin…”
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