Search Results - "Hirvonen, Ari"
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The effect of SLC6A3 variable number of tandem repeats and methylation levels on individual susceptibility to start tobacco smoking and on the ability of smokers to quit smoking
Published in Pharmacogenetics and genomics (01-08-2020)“…OBJECTIVENicotine acts through the dopamine pathway in the brain affecting reward processing through cigarette consumption. Thus, both genetic and epigenetic…”
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The genotypes and methylation of MAO genes as factors behind smoking behavior
Published in Pharmacogenetics and genomics (01-11-2017)“…OBJECTIVESmoking dependence is the main cause for tobacco-related illnesses. The addiction-causing substance in tobacco, nicotine, acts through the dopamine…”
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3
Physiological and autonomic stress responses after prolonged sleep restriction and subsequent recovery sleep in healthy young men
Published in Sleep and biological rhythms (01-01-2018)“…Purpose Sleep restriction is increasingly common and associated with the development of health problems. We investigated how the neuroendocrine stress systems…”
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4
Genetic influences on hand osteoarthritis in Finnish women--a replication study of candidate genes
Published in PloS one (13-05-2014)“…Our aims were to replicate some previously reported associations of single nucleotide polymorphisms (SNPs) in five genes (A2BP1, COG5, GDF5, HFE, ESR1) with…”
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5
Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study
Published in PloS one (23-04-2013)“…Asbestos exposure is the main risk factor for malignant pleural mesothelioma (MPM), a rare aggressive tumor. Nevertheless, only 5-17% of those exposed to…”
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6
Effect of genotype and methylation of CYP2D6 on smoking behaviour
Published in Pharmacogenetics and genomics (01-11-2015)“…OBJECTIVECigarette smoking is one of the most influential environmental factors affecting the DNA methylation patterns. The addiction-causing substance of…”
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7
SULT1A1 rs9282861 polymorphism-a potential modifier of efficacy of the systemic adjuvant therapy in breast cancer?
Published in BMC cancer (18-06-2012)“…Sulfotransferase 1A1 (SULT1A1) participates in the elimination of 4-hydroxy-tamoxifen (4-OH-TAM), which is one of the major active metabolites of tamoxifen…”
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8
Prolonged Sleep Restriction Affects Glucose Metabolism in Healthy Young Men
Published in International Journal of Endocrinology (01-01-2010)“…This study identifies the effects of sleep restriction and subsequent recovery sleep on glucose homeostasis, serum leptin levels, and feelings of subjective…”
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Associations Between Glutathione-S-Transferase Genotypes and Bronchial Hyperreactivity Patients With Di-isocyanate Induced Asthma. A Follow-Up Study
Published in Frontiers in medicine (09-10-2019)“…Introduction: Di-isocyanates TDI (toluene di-isocyanate), MDI (diphenylmethane di-isocyanate), and HDI (hexamethylene di-isocyanate) are the most common…”
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10
Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity
Published in Carcinogenesis (New York) (01-06-2002)“…Mutagen sensitivity, measuring the extent of chromosome damage induced by an in vitro treatment of peripheral lymphocytes with bleomycin, has been associated…”
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Glutathione S-Transferase M1, M3, P1, and T1 Genetic Polymorphisms and Susceptibility to Breast Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-03-2001)“…This study was undertaken to examine if glutathione S -transferase (GST) M1 , M3 , P1 , and T1 genotypes affected breast cancer risk in Finnish women. The…”
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Correction: genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study
Published in PloS one (03-06-2015)Get full text
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13
Association Between Interleukin 1 Gene Cluster Polymorphisms and Bilateral Distal Interphalangeal Osteoarthritis
Published in Journal of rheumatology (01-09-2009)“…Objective. To examine the association of the interleukin 1 gene ( IL1 ) cluster polymorphisms and their haplotypes with bilateral distal interphalangeal joint…”
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14
SERPINE2 haplotype as a risk factor for panlobular type of emphysema
Published in BMC genetics (07-12-2011)“…SERPINE2 (serpin peptidase inhibitor, clade E, member 2) has previously been identified as a positional candidate gene for chronic obstructive pulmonary…”
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15
Fear and Anxiety: The Nationalist and Racist Politics of Fantasy
Published in Law and critique (01-11-2017)“…Crises have become a new normality. This normality is turned into grounds for the politics of fear. The hegemonic principle of the politics of fear is…”
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Genetic Polymorphisms of SULT1A1 and SULT1E1 and the Risk and Survival of Breast Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-05-2005)“…We examined whether common single nucleotide polymorphisms (SNP) in SULT1A1 (c.779G>A, *14A>G, and *85C>T) and SULT1E1 (IVS1-447C>A, IVS4-1653T>C, and *959G>A)…”
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Steroid Metabolism Gene CYP17 Polymorphism and the Development of Breast Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-12-2000)“…The potential role of the polymorphism in the CYP17 gene was evaluated in a case-control study with 483 incident breast cancer patients and 482 population…”
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Polymorphic Catechol-O-methyltransferase Gene and Breast Cancer Risk
Published in Cancer epidemiology, biomarkers & prevention (01-06-2001)“…We examined 483 Finnish breast cancer cases and 482 population controls to determine the potential effect of catechol- O -methyltransferase ( COMT ) genotype…”
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Influence of DNA repair gene polymorphisms on the yield of chromosomal aberrations
Published in Environmental and molecular mutagenesis (01-10-2005)“…We evaluated the influence of several DNA repair gene polymorphisms on the frequency of chromosomal aberrations (CAs) analyzed in peripheral lymphocytes, using…”
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Sister Chromatid Exchanges and Micronuclei in Peripheral Lymphocytes of Shoe Factory Workers Exposed to Solvents
Published in Environmental health perspectives (01-04-2002)“…We examined sister chromatid exchanges (SCEs) and micronuclei (MN; cytokinesis-block method) in cultured peripheral lymphocytes from 52 female workers of two…”
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