Search Results - "Hirth, Sofia"
-
1
Developmental alterations in centrosome integrity contribute to the post-mitotic state of mammalian cardiomyocytes
Published in eLife (06-08-2015)“…Mammalian cardiomyocytes become post-mitotic shortly after birth. Understanding how this occurs is highly relevant to cardiac regenerative therapy. Yet, how…”
Get full text
Journal Article -
2
Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart
Published in PloS one (08-03-2016)“…An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads…”
Get full text
Journal Article -
3
The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation
Published in Biochemical and biophysical research communications (02-09-2016)“…In search for novel key regulators of cardiac valve formation, we isolated the zebrafish cardiac valve mutant ping pong (png). We find that an insertional…”
Get full text
Journal Article -
4
In vivo characterization of human myofibrillar myopathy genes in zebrafish
Published in Biochemical and biophysical research communications (29-05-2015)“…Myofibrillar myopathies (MFM) are progressive diseases of human heart and skeletal muscle with a severe impact on life quality and expectancy of affected…”
Get full text
Journal Article -
5
Semi-automated detection of fractional shortening in zebrafish embryo heart videos
Published in Current directions in biomedical engineering (01-09-2016)“…Quantifying cardiac functions in model organisms like embryonic zebrafish is of high importance in small molecule screens for new therapeutic compounds. One…”
Get full text
Journal Article -
6
Paxillin and Focal Adhesion Kinase
Published in PloS one (08-03-2016)“…An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads…”
Get full text
Journal Article -
7
Automatic zebrafish heartbeat detection and analysis for zebrafish embryos
Published in Zebrafish (01-08-2014)“…A fully automatic detection and analysis method of heartbeats in videos of nonfixed and nonanesthetized zebrafish embryos is presented. This method reduces the…”
Get more information
Journal Article -
8
The Arabidopsis NIMIN proteins affect NPR1 differentially
Published in Frontiers in plant science (12-04-2013)“…NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) is the central regulator of the pathogen defense reaction systemic acquired resistance (SAR). NPR1 acts by…”
Get full text
Journal Article