Search Results - "Hirst, L."

Emotional adaptation to relationship dissolution in parents and non-parents: A new conceptual model and measure by Millings, Abigail, Hirst, Shannon L, Sirois, Fuschia, Houlston, Catherine

“…Relationship dissolution can cause declines in emotional well-being, particularly if there are children involved. Individuals' capacity to cope with the…”
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Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer by Rugo, Hope S, Olopade, Olufunmilayo I, DeMichele, Angela, Yau, Christina, van ’t Veer, Laura J, Buxton, Meredith B, Hogarth, Michael, Hylton, Nola M, Paoloni, Melissa, Perlmutter, Jane, Symmans, W. Fraser, Yee, Douglas, Chien, A. Jo, Wallace, Anne M, Kaplan, Henry G, Boughey, Judy C, Haddad, Tufia C, Albain, Kathy S, Liu, Minetta C, Isaacs, Claudine, Khan, Qamar J, Lang, Julie E, Viscusi, Rebecca K, Pusztai, Lajos, Moulder, Stacy L, Chui, Stephen Y, Kemmer, Kathleen A, Elias, Anthony D, Edmiston, Kirsten K, Euhus, David M, Haley, Barbara B, Nanda, Rita, Northfelt, Donald W, Tripathy, Debasish, Wood, William C, Ewing, Cheryl, Schwab, Richard, Lyandres, Julia, Davis, Sarah E, Hirst, Gillian L, Sanil, Ashish, Berry, Donald A, Esserman, Laura J

“…Using an adaptive trial design to minimize the exposure of patients to inactive agents and to detect more active regimens sooner, investigators found that…”
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Adaptive Randomization of Neratinib in Early Breast Cancer by Park, John W, Liu, Minetta C, Yee, Douglas, Yau, Christina, van ’t Veer, Laura J, Symmans, W. Fraser, Paoloni, Melissa, Perlmutter, Jane, Hylton, Nola M, Hogarth, Michael, DeMichele, Angela, Buxton, Meredith B, Chien, A. Jo, Wallace, Anne M, Boughey, Judy C, Haddad, Tufia C, Chui, Stephen Y, Kemmer, Kathleen A, Kaplan, Henry G, Isaacs, Claudine, Nanda, Rita, Tripathy, Debasish, Albain, Kathy S, Edmiston, Kirsten K, Elias, Anthony D, Northfelt, Donald W, Pusztai, Lajos, Moulder, Stacy L, Lang, Julie E, Viscusi, Rebecca K, Euhus, David M, Haley, Barbara B, Khan, Qamar J, Wood, William C, Melisko, Michelle, Schwab, Richard, Helsten, Teresa, Lyandres, Julia, Davis, Sarah E, Hirst, Gillian L, Sanil, Ashish, Esserman, Laura J, Berry, Donald A

“…Among patients with HER2-positive, hormone-receptor–negative locally advanced breast cancer, the addition of neratinib to standard therapy resulted in higher…”
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CaMKII regulates neuromuscular activity and survival of the human blood fluke Schistosoma mansoni by Hirst, Natasha L., Lawton, Scott P., Walker, Anthony J.

“…Calcium/calmodulin dependant protein kinase II (CaMKII), an important transducer of Ca 2+ signals, orchestrates multiple cellular functions in animals. Here we…”
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Intrinsic radiation tolerance of ultra-thin GaAs solar cells by Hirst, L. C., Yakes, M. K., Warner, J. H., Bennett, M. F., Schmieder, K. J., Walters, R. J., Jenkins, P. P.

“…Radiation tolerance is a critical performance criterion of photovoltaic devices for space power applications. In this paper we demonstrate the intrinsic…”
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Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial by Clark, Amy S., Yau, Christina, Wolf, Denise M., Petricoin, Emanuel F., van ‘t Veer, Laura J., Yee, Douglas, Moulder, Stacy L., Wallace, Anne M., Chien, A. Jo, Isaacs, Claudine, Boughey, Judy C., Albain, Kathy S., Kemmer, Kathleen, Haley, Barbara B., Han, Hyo S., Forero-Torres, Andres, Elias, Anthony, Lang, Julie E., Ellis, Erin D., Yung, Rachel, Tripathy, Debu, Nanda, Rita, Wulfkuhle, Julia D., Brown-Swigart, Lamorna, Gallagher, Rosa I., Helsten, Teresa, Roesch, Erin, Ewing, Cheryl A., Alvarado, Michael, Crane, Erin P., Buxton, Meredith, Clennell, Julia L., Paoloni, Melissa, Asare, Smita M., Wilson, Amy, Hirst, Gillian L., Singhrao, Ruby, Steeg, Katherine, Asare, Adam, Matthews, Jeffrey B., Berry, Scott, Sanil, Ashish, Melisko, Michelle, Perlmutter, Jane, Rugo, Hope S., Schwab, Richard B., Symmans, W. Fraser, Hylton, Nola M., Berry, Donald A., Esserman, Laura J., DeMichele, Angela M.

“…HER2-targeted therapy dramatically improves outcomes in early breast cancer. Here we report the results of two HER2-targeted combinations in the neoadjuvant…”
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Experimental demonstration of hot-carrier photo-current in an InGaAs quantum well solar cell by Hirst, L. C., Walters, R. J., Führer, M. F., Ekins-Daukes, N. J.

“…An unambiguous observation of hot-carrier photocurrent from an InGaAs single quantum well solar cell is reported. Simultaneous photo-current and…”
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Suitability of memory aids and strategies for people with posterior cortical atrophy: protocol for a scoping review by Burbaite, A, Leeworthy, S, Hirst, L, Mioshi, E, Clare, L, Ahmed, S

“…Posterior cortical atrophy (PCA) is a neurodegenerative syndrome characterised by progressive visuospatial and visuoperceptual impairment. Recent research…”
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Stereotactic body radiotherapy for early-stage lung cancer: a systematic review on the choice of photon energy and linac flattened/unflattened beams by Gill, Ashlesha, Hirst, Andrew L, Rowshanfarzad, Pejman, Gill, Suki, Bucknell, Nicholas, Dass, Joshua, Sabet, Mahsheed

“…SBRT is an effective local treatment for patients with early-stage non-small cell lung cancer (NSCLC). This treatment is currently used in patients who have…”
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Ectopic canine sequelae by Bradley, H., Hirst, L., Collard, M.

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Spectral and polarization modulation of quantum dot emission in a one-dimensional liquid crystal photonic cavity by Rodarte, A. L., Gray, C., Hirst, L. S., Ghosh, S.

“…We demonstrate spectral and polarization modulation of chemically synthesized core-shell CdSe/ZnS quantum dots (QDs) embedded in a one-dimensional photonic…”
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Deep phosphoproteome analysis of Schistosoma mansoni leads development of a kinomic array that highlights sex-biased differences in adult worm protein phosphorylation by Hirst, Natasha L, Nebel, Jean-Christophe, Lawton, Scott P, Walker, Anthony J

“…Although helminth parasites cause enormous suffering worldwide we know little of how protein phosphorylation, one of the most important post-translational…”
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B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer by Steenbruggen, Tessa G, Wolf, Denise M, Campbell, Michael J, Sanders, Joyce, Cornelissen, Sten, Thijssen, Bram, Salgado, Roberto A, Yau, Christina, O-Grady, Nick, Basu, Amrita, Bhaskaran, Rajith, Mittempergher, Lorenza, Hirst, Gillian L, Coppe, Jean-Philippe, Kok, Marleen, Sonke, Gabe S, van 't Veer, Laura J, Horlings, Hugo M

“…Background Despite major improvements in treatment of HER2-positive metastatic breast cancer (MBC), only few patients achieve complete remission and remain…”
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CSF oligoclonal band status informs prognosis in multiple sclerosis: a case control study of 100 patients by Joseph, F G, Hirst, C L, Pickersgill, T P, Ben-Shlomo, Y, Robertson, N P, Scolding, N J

“…Objective:Oligoclonal band (OCB) negative multiple sclerosis (MS) is well recognised but uncommon, studied in only a few usually small case series. These…”
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Systemic complement profiling in multiple sclerosis as a biomarker of disease state by Ingram, G, Hakobyan, S, Hirst, CL, Harris, CL, Loveless, S, Mitchell, JP, Pickersgill, TP, Robertson, NP, Morgan, BP

“…Background: There is increasing evidence of significant and dynamic systemic activation and upregulation of complement in multiple sclerosis (MS), which may…”
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Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes by Yu, Katharine, Basu, Amrita, Yau, Christina, Wolf, Denise M, Goodarzi, Hani, Bandyopadhyay, Sourav, Korkola, James E, Hirst, Gillian L, Asare, Smita, DeMichele, Angela, Hylton, Nola, Yee, Douglas, Esserman, Laura, van 't Veer, Laura, Sirota, Marina

“…Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant…”
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Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer by Quigley, David A., Kandyba, Eve, Huang, Phillips, Halliwill, Kyle D., Sjölund, Jonas, Pelorosso, Facundo, Wong, Christine E., Hirst, Gillian L., Wu, Di, Delrosario, Reyno, Kumar, Atul, Balmain, Allan

“…Inherited germline polymorphisms can cause gene expression levels in normal tissues to differ substantially between individuals. We present an analysis of the…”
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Complement regulator factor H as a serum biomarker of multiple sclerosis disease state by Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire L., Harris, Claire L., Pickersgill, Trevor P., Cossburn, Mark D., Loveless, Sam, Robertson, Neil P., Morgan, Bryan Paul

“…Multiple sclerosis has a variable phenotypic presentation and subsequent disease course that, although unpredictable at disease onset, is of crucial importance…”
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Lifting the lid on toilet plume aerosol: A literature review with suggestions for future research by Johnson, David L., PhD, Mead, Kenneth R., PhD, Lynch, Robert A., PhD, Hirst, Deborah V.L., PhD

“…Background The potential risks associated with “toilet plume” aerosols produced by flush toilets is a subject of continuing study. This review examines the…”
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Immediate effects of alpha/theta and sensory-motor rhythm feedback on music performance by Gruzelier, J.H., Hirst, L., Holmes, P., Leach, J.

“…This is one of a series of investigations comparing two EEG-neurofeedback protocols – Alpha/theta (A/T) and Sensory-Motor Rhythm (SMR) – for performance…”
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