Search Results - "Hirotsugu Yamada"

A Deep Learning Approach for Assessment of Regional Wall Motion Abnormality From Echocardiographic Images by Kusunose, Kenya, Abe, Takashi, Haga, Akihiro, Fukuda, Daiju, Yamada, Hirotsugu, Harada, Masafumi, Sata, Masataka

“…This study investigated whether a deep convolutional neural network (DCNN) could provide improved detection of regional wall motion abnormalities (RWMAs) and…”
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Canagliflozin Prevents Diabetes-Induced Vascular Dysfunction in ApoE-Deficient Mice by Rahadian, Arief, Fukuda, Daiju, Salim, Hotimah Masdan, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Sata, Masataka

“…Aim: Recent studies have demonstrated that selective sodium–glucose cotransporter 2 inhibitors (SGLT2is) reduce cardiovascular events, although their mechanism…”
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Empagliflozin ameliorates endothelial dysfunction and suppresses atherogenesis in diabetic apolipoprotein E-deficient mice by Ganbaatar, Byambasuren, Fukuda, Daiju, Shinohara, Masakazu, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Hirata, Ken-ichi, Sata, Masataka

“…Recent studies reported cardioprotective effects of sodium glucose co-transporter 2 (SGLT2) inhibitors; however, the underlying mechanisms are still obscure…”
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A Selective Mineralocorticoid Receptor Blocker, Esaxerenone, Attenuates Vascular Dysfunction in Diabetic C57BL/6 Mice by Munkhjargal, Uugantsetseg, Fukuda, Daiju, Ganbaatar, Byambasuren, Suto, Kumiko, Matsuura, Tomomi, Ise, Takayuki, Kusunose, Kenya, Yamaguchi, Koji, Yagi, Shusuke, Yamada, Hirotsugu, Soeki, Takeshi, Wakatsuki, Tetsuzo, Sata, Masataka

“…Aims: Pharmacological blockade of mineralocorticoid receptors (MRs) is a potential therapeutic approach to reduce cardiovascular complications since MRs play a…”
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STING, a cytosolic DNA sensor, plays a critical role in atherogenesis: a link between innate immunity and chronic inflammation caused by lifestyle-related diseases by Pham, Phuong Tran, Fukuda, Daiju, Nishimoto, Sachiko, Kim-Kaneyama, Joo-Ri, Lei, Xiao-Feng, Takahashi, Yutaka, Sato, Tomohito, Tanaka, Kimie, Suto, Kumiko, Kawabata, Yutaka, Yamaguchi, Koji, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Wakatsuki, Tetsuzo, Shimada, Kenji, Kanematsu, Yasuhisa, Takagi, Yasushi, Shimabukuro, Michio, Setou, Mitsutoshi, Barber, Glen N, Sata, Masataka

“…Abstract Aims Lifestyle-related diseases promote atherosclerosis, a chronic inflammatory disease; however, the molecular mechanism remains largely unknown…”
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Inhibition of S1P Receptor 2 Attenuates Endothelial Dysfunction and Inhibits Atherogenesis in Apolipoprotein E-Deficient Mice by Ganbaatar, Byambasuren, Fukuda, Daiju, Shinohara, Masakazu, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Hirata, Ken-ichi, Sata, Masataka

“…Aim: The bioactive lipid, sphingosine-1-phosphate (S1P), has various roles in the physiology and pathophysiology of many diseases. There are five S1P…”
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Intimal Sarcoma of the Pulmonary Artery as an Embolic Cause of Sudden Death by Yagi, Shusuke, Hara, Tomoya, Yamada, Hirotsugu, Kusunose, Kenya, Ise, Takayuki, Sata, Masataka

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Activated Factor X Signaling Pathway via Protease-Activated Receptor 2 Is a Novel Therapeutic Target for Preventing Atrial Fibrillation by Matsuura, Tomomi, Soeki, Takeshi, Fukuda, Daiju, Uematsu, Etsuko, Tobiume, Takeshi, Hara, Tomoya, Kusunose, Kenya, Ise, Takayuki, Yamaguchi, Koji, Yagi, Shusuke, Yamada, Hirotsugu, Wakatsuki, Tetsuzo, Sata, Masataka

“…Background:Activated factor X (FXa), which contributes to chronic inflammation via protease-activated receptor 2 (PAR2), might play an important role in atrial…”
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Report of the American College of Cardiology (ACC) Scientific Sessions 2013, San Francisco: Highlighting Late-Breaking Trials by Yamada, Hirotsugu

“…The American College of Cardiology’s (ACC) 62nd Annual Scientific Session was held at the Moscone Center, San Francisco, from March 9–11, 2013. The meeting…”
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How to standardize the measurement of left ventricular ejection fraction by Kusunose, Kenya, Zheng, Robert, Yamada, Hirotsugu, Sata, Masataka

“…Despite recent advances in imaging for myocardial deformation, left ventricular ejection fraction (LVEF) is still the most important index for systolic…”
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Febuxostat does not delay progression of carotid atherosclerosis in patients with asymptomatic hyperuricemia: A randomized, controlled trial by Tanaka, Atsushi, Taguchi, Isao, Teragawa, Hiroki, Ishizaka, Nobukazu, Kanzaki, Yumiko, Tomiyama, Hirofumi, Sata, Masataka, Sezai, Akira, Eguchi, Kazuo, Kato, Toru, Toyoda, Shigeru, Ishibashi, Ryoichi, Kario, Kazuomi, Ishizu, Tomoko, Ueda, Shinichiro, Maemura, Koji, Higashi, Yukihito, Yamada, Hirotsugu, Ohishi, Mitsuru, Yokote, Kotaro, Murohara, Toyoaki, Oyama, Jun-Ichi, Node, Koichi

“…An elevated level of serum uric acid (SUA) is associated with an increased risk of cardiovascular disease. Pharmacological intervention with urate-lowering…”
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Effects of the Addition of Eicosapentaenoic Acid to Strong Statin Therapy on Inflammatory Cytokines and Coronary Plaque Components Assessed by Integrated Backscatter Intravascular Ultrasound by Niki, Toshiyuki, Wakatsuki, Tetsuzo, Yamaguchi, Koji, Taketani, Yoshio, Oeduka, Hiroyasu, Kusunose, Kenya, Ise, Takayuki, Iwase, Takashi, Yamada, Hirotsugu, Soeki, Takeshi, Sata, Masataka

“…Background:The effects of eicosapentaenoic acid (EPA) on coronary artery disease have been previously reported; however, those of the addition of EPA to strong…”
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Deep Learning for Assessment of Left Ventricular Ejection Fraction from Echocardiographic Images by Kusunose, Kenya, Haga, Akihiro, Yamaguchi, Natsumi, Abe, Takashi, Fukuda, Daiju, Yamada, Hirotsugu, Harada, Masafumi, Sata, Masataka

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Rivaroxaban, a specific FXa inhibitor, improved endothelium-dependent relaxation of aortic segments in diabetic mice by Pham, Phuong Tran, Fukuda, Daiju, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Shimabukuro, Michio, Sata, Masataka

“…Activated factor X (FXa) plays a central role in the coagulation cascade, while it also mediates vascular function through activation of protease-activated…”
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Pemafibrate, A Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator, Reduces Plasma Eicosanoid Levels and Ameliorates Endothelial Dysfunction in Diabetic Mice by Suto, Kumiko, Fukuda, Daiju, Shinohara, Masakazu, Ganbaatar, Byambasuren, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Hirata, Ken-ichi, Sata, Masataka

“…Aims: Various pathological processes related to diabetes cause endothelial dysfunction. Eicosanoids derived from arachidonic acid (AA) have roles in vascular…”
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Epicardial Fat and Pericardial Fat Surrounding the Heart Have Different Characteristics by Hirata, Yukina, Yamada, Hirotsugu, Sata, Masataka

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Association of Local Epicardial Adipose Tissue Depots and Left Ventricular Diastolic Performance in Patients With Preserved Left Ventricular Ejection Fraction by Maimaituxun, Gulinu, Yamada, Hirotsugu, Fukuda, Daiju, Yagi, Shusuke, Kusunose, Kenya, Hirata, Yukina, Nishio, Susumu, Soeki, Takeshi, Masuzaki, Hiroaki, Sata, Masataka, Shimabukuro, Michio

“…Background:Although full-volume quantification of epicardial adipose tissue (EAT) is a predictor of LV diastolic dysfunction (LVDD), how localized EAT depots…”
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Association of Microluminal Structures Assessed by Optical Coherence Tomography With Local Inflammation in Adjacent Epicardial Adipose Tissue and Coronary Plaque Characteristics in Fresh Cadavers by Kawabata, Yutaka, Wakatsuki, Tetsuzo, Yamaguchi, Koji, Fukuda, Daiju, Ito, Hiroyuki, Matsuura, Tomomi, Kusunose, Kenya, Ise, Takayuki, Yagi, Shusuke, Yamada, Hirotsugu, Soeki, Takeshi, Tsuruo, Yoshihiro, Sata, Masataka

“…Background: Coronary intraplaque microluminal structures (MS) are associated with plaque vulnerability, and the inward progression of vascular inflammation…”
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Prognostic Value of Frailty and Diastolic Dysfunction in Elderly Patients by Kusunose, Kenya, Okushi, Yuichiro, Yamada, Hirotsugu, Nishio, Susumu, Torii, Yuta, Hirata, Yukina, Saijo, Yoshihito, Ise, Takayuki, Yamaguchi, Koji, Yagi, Shusuke, Soeki, Takeshi, Wakatsuki, Tetsuzo, Sata, Masataka

“…Background:High prevalence of frailty and of diastolic dysfunction (DD) in heart failure and high mortality in frail adults have been noted. We characterized…”
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Does Echocardiographic Epicardial Adipose Tissue Thickness become a Useful Biomarker? by Yamada, Hirotsugu, Sata, Masataka

“…Epicardial adipose tissue (EAT) is ectopic visceral fat surrounding the heart that is located close to the coronary arteries. Excessive EAT has been reported…”
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