Search Results - "Hiroshi Ikegami"

Which comes first in type 1 diabetes: Autoimmunity or dysglycemia? by Ikegami, Hiroshi

“…A recent study by Warncke et al. suggested that islet autoimmunity is associated with or preceded by insults or changes to the pancreatic islets that impair…”
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β‐Cell failure in diabetes: Common susceptibility and mechanisms shared between type 1 and type 2 diabetes by Ikegami, Hiroshi, Babaya, Naru, Noso, Shinsuke

“…Diabetes mellitus is etiologically classified into type 1, type 2 and other types of diabetes. Despite distinct etiologies and pathogenesis of these subtypes,…”
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Glycemic Control and Insulin Improve Muscle Mass and Gait Speed in Type 2 Diabetes: The MUSCLES-DM Study by Sugimoto, Ken, Ikegami, Hiroshi, Takata, Yasunori, Katsuya, Tomohiro, Fukuda, Masahiro, Akasaka, Hiroshi, Tabara, Yasuharu, Osawa, Haruhiko, Hiromine, Yoshihisa, Rakugi, Hiromi

“…Type 2 diabetes is a risk factor for sarcopenia. Evidence on the prevention of sarcopenia using blood glucose–lowering therapy is limited. We aimed to examine…”
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Insulin‐dependent diabetes mellitus in older adults: Current status and future prospects by Ikegami, Hiroshi, Hiromine, Yoshihisa, Noso, Shinsuke

“…The recent increase in life expectancy has resulted in an increase in the number of older adults with diabetes mellitus. In addition to type 2 diabetes, in…”
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Hyperglycemia in non‐obese patients with type 2 diabetes is associated with low muscle mass: The Multicenter Study for Clarifying Evidence for Sarcopenia in Patients with Diabetes Mellitus by Sugimoto, Ken, Tabara, Yasuharu, Ikegami, Hiroshi, Takata, Yasunori, Kamide, Kei, Ikezoe, Tome, Kiyoshige, Eri, Makutani, Yukako, Onuma, Hiroshi, Gondo, Yasuyuki, Ikebe, Kazunori, Ichihashi, Noriaki, Tsuboyama, Tadao, Matsuda, Fumihiko, Kohara, Katsuhiko, Kabayama, Mai, Fukuda, Masahiro, Katsuya, Tomohiro, Osawa, Haruhiko, Hiromine, Yoshihisa, Rakugi, Hiromi

“…Aims/Introduction Hyperglycemia is a risk factor for sarcopenia when comparing individuals with and without diabetes. However, no studies have investigated…”
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The SAGE study: Global observational analysis of glycaemic control, hypoglycaemia and diabetes management in T1DM by Renard, Eric, Ikegami, Hiroshi, Daher Vianna, André Gustavo, Pozzilli, Paolo, Brette, Sandrine, Bosnyak, Zsolt, Lauand, Felipe, Peters, Anne, Pilorget, Valerie, Jurišić‐Eržen, Dubravka, Kesavadev, Jothydev, Seufert, Jochen, Wilmot, Emma G.

“…Aims To describe glycaemic control and diabetes management in adults with type 1 diabetes (T1DM), in a real‐life global setting. Materials and Methods Study of…”
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Glucose Metabolism After Pancreatectomy: Opposite Extremes Between Pancreaticoduodenectomy and Distal Pancreatectomy by Niwano, Fumimaru, Babaya, Naru, Hiromine, Yoshihisa, Matsumoto, Ippei, Kamei, Keiko, Noso, Shinsuke, Taketomo, Yasunori, Takeyama, Yoshifumi, Kawabata, Yumiko, Ikegami, Hiroshi

“…Abstract Context The rate of glucose metabolism changes drastically after partial pancreatectomy. Objective This work aims to analyze changes in patients’…”
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Three-Year Observation of Glucose Metabolism After Pancreaticoduodenectomy: A Single-Center Prospective Study in Japan by Niwano, Fumimaru, Babaya, Naru, Hiromine, Yoshihisa, Matsumoto, Ippei, Kamei, Keiko, Taketomo, Yasunori, Yoshida, Sawa, Takeyama, Yoshifumi, Noso, Shinsuke, Ikegami, Hiroshi

“…Context: The glucose tolerance of patients changes considerably from before to after pancreaticoduodenectomy wherein approximately half of the pancreas is…”
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Glucose values from the same continuous glucose monitoring sensor significantly differ among readers with different generations of algorithm by Babaya, Naru, Noso, Shinsuke, Hiromine, Yoshihisa, Taketomo, Yasunori, Niwano, Fumimaru, Yoshida, Sawa, Yasutake, Sara, Kawabata, Yumiko, Maeda, Norikazu, Ikegami, Hiroshi

“…Continuous glucose monitoring (CGM) values obtained from CGM systems using the same sensor but with different internal algorithms (the first- and…”
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Novel loci for hyperglycemia identified by QTL mapping of longitudinal phenotypes and congenic analysis by Babaya, Naru, Itoi-Babaya, Michiko, Ueda, Hironori, Kobayashi, Misato, Noso, Shinsuke, Hiromine, Yoshihisa, Ishikawa, Akira, Fujisawa, Tomomi, Ikegami, Hiroshi

“…We previously reported that four hyperglycemia loci are located on three chromosomes in the Nagoya-Shibata-Yasuda (NSY) mouse model, commonly used to study…”
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Characteristics and clinical course of type 1 diabetes mellitus related to anti-programmed cell death-1 therapy by Baden, Megu Yamaguchi, Imagawa, Akihisa, Abiru, Norio, Awata, Takuya, Ikegami, Hiroshi, Uchigata, Yasuko, Oikawa, Yoichi, Osawa, Haruhiko, Kajio, Hiroshi, Kawasaki, Eiji, Kawabata, Yumiko, Kozawa, Junji, Shimada, Akira, Takahashi, Kazuma, Tanaka, Shoichiro, Chujo, Daisuke, Fukui, Tomoyasu, Miura, Junnosuke, Yasuda, Kazuki, Yasuda, Hisafumi, Kobayashi, Tetsuro, Hanafusa, Toshiaki

“…Aims We conducted a national survey to clarify the characteristics and clinical course of type 1 diabetes related to anti-programmed cell death-1 therapy…”
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Fulminant type 1 diabetes associated with Isolated ACTH deficiency induced by anti-programmed cell death 1 antibody—insight into the pathogenesis of autoimmune endocrinopathy by Okahata, Sumie, Sakamoto, Kentaro, Mitsumatsu, Takako, Kondo, Yuko, Noso, Shinsuke, Ikegami, Hiroshi, Shiba, Teruo

“…Therapeutic blocking antibodies against programmed death 1 (PD1) and cytotoxic T-lymphocyte antigen 4 (CTLA4) are applied for advanced cancer therapy, but…”
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Glycemic Excursion and Insulin Action Revealed in a Rare Case of Type 1 Diabetes Complicated with Short Bowel Syndrome by Hiromine, Yoshihisa, Noso, Shinsuke, Babaya, Naru, Taketomo, Yasunori, Niwano, Fumimaru, Okuda, Yuki, Yasutake, Sara, Minohara, Tatsuro, Tsuda, Naonobu, Hama, Yuichiro, Ikegami, Hiroshi

“…We herein report a 52-year-old woman with a rare combination of short bowel syndrome due to massive resection of the small intestine and complete loss of…”
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Relationship of continuous glucose monitoring-related metrics with HbA1c and residual β-cell function in Japanese patients with type 1 diabetes by Babaya, Naru, Noso, Shinsuke, Hiromine, Yoshihisa, Taketomo, Yasunori, Niwano, Fumimaru, Yoshida, Sawa, Yasutake, Sara, Kawabata, Yumiko, Ikegami, Hiroshi

“…The targets for continuous glucose monitoring (CGM)-derived metrics were recently set; however, studies on CGM data over a long period with stable glycemic…”
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Poor glycemic control rather than types of diabetes is a risk factor for sarcopenia in diabetes mellitus: The MUSCLES‐DM study by Hiromine, Yoshihisa, Noso, Shinsuke, Rakugi, Hiromi, Sugimoto, Ken, Takata, Yasunori, Katsuya, Tomohiro, Fukuda, Masahiro, Akasaka, Hiroshi, Osawa, Haruhiko, Tabara, Yasuharu, Ikegami, Hiroshi

“…ABSTRACT Aims/Introduction Though poor glycemic control and insulin treatment are reported to be associated with sarcopenia in type 2 diabetes, type 1 diabetes…”
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Confirmation of Multiple Risk Loci and Genetic Impacts by a Genome-Wide Association Study of Type 2 Diabetes in the Japanese Population by TAKEUCHI, Fumihiko, SERIZAWA, Masakuni, NAKASHIMA, Naoki, NAWATA, Hajime, NAKAMURA, Jiro, KONO, Suminori, TAKAYANAGI, Ryoichi, KATO, Norihiro, YAMAMOTO, Ken, FUJISAWA, Tomomi, NAKASHIMA, Eitaro, OHNAKA, Keizo, IKEGAMI, Hiroshi, SUGIYAMA, Takao, KATSUYA, Tomohiro, MIYAGISHI, Makoto

“…Confirmation of Multiple Risk Loci and Genetic Impacts by a Genome-Wide Association Study of Type 2 Diabetes in the Japanese Population Fumihiko Takeuchi 1 , 2…”
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Metabolic signatures of β‐cell destruction in type 1 diabetes by Noso, Shinsuke, Babaya, Naru, Hiromine, Yoshihisa, Taketomo, Yasunori, Niwano, Fumimaru, Yoshida, Sawa, Ikegami, Hiroshi

“…ABSTRACT Aims/Introduction In the development of type 1 diabetes, metabolites are significantly altered and might be involved in β‐cell destruction and…”
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Recommendations on the proper use of SGLT2 inhibitors

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A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia by Ohno, Tamio, Miyasaka, Yuki, Yoshida, Kanta, Kobayashi, Misato, Horio, Fumihiko, Yokoi, Norihide, Mizuno, Masashi, Ikegami, Hiroshi

“…Various mouse models of type 2 diabetes have been established, but few of these show early onset and persistent hyperglycemia. We have established a congenic…”
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Bivalent GAD autoantibody ELISA improves clinical utility and risk prediction for adult autoimmune diabetes by Kawasaki, Eiji, Shimada, Akira, Imagawa, Akihisa, Abiru, Norio, Awata, Takuya, Oikawa, Yoichi, Osawa, Haruhiko, Kawabata, Yumiko, Kozawa, Junji, Kobayashi, Tetsuro, Takahashi, Kazuma, Chujo, Daisuke, Fukui, Tomoyasu, Miura, Junnosuke, Yasuda, Kazuki, Yasuda, Hisafumi, Kajio, Hiroshi, Hanafusa, Toshiaki, Ikegami, Hiroshi

“…Aim/Introduction To investigate the differences in the clinical significance and glutamic acid decarboxylase autoantibody (GADA) affinity between RIA…”
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