Search Results - "Hirose, Masahito"

Renal macrophage migration and crystal phagocytosis via inflammatory‐related gene expression during kidney stone formation and elimination in mice: Detection by association analysis of stone‐related gene expression and microstructural observation by Okada, Atsushi, Yasui, Takahiro, Fujii, Yasuhiro, Niimi, Kazuhiro, Hamamoto, Shuzo, Hirose, Masahito, Kojima, Yoshiyuki, Itoh, Yasunori, Tozawa, Keiichi, Hayashi, Yutaro, Kohri, Kenjiro

“…Mice have a strong ability to eliminate renal calcium oxalate crystals, and our previous examination indicated a susceptibility in which monocyte‐macrophage…”
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Effect of adiponectin on kidney crystal formation in metabolic syndrome model mice via inhibition of inflammation and apoptosis by Fujii, Yasuhiro, Okada, Atsushi, Yasui, Takahiro, Niimi, Kazuhiro, Hamamoto, Shuzo, Hirose, Masahito, Kubota, Yasue, Tozawa, Keiichi, Hayashi, Yutaro, Kohri, Kenjiro

“…The aims of the present study were to elucidate a possible mechanism of kidney crystal formation by using a metabolic syndrome (MetS) mouse model and to assess…”
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Renal tubular epithelial cell injury and oxidative stress induce calcium oxalate crystal formation in mouse kidney by Hirose, Masahito, Yasui, Takahiro, Okada, Atsushi, Hamamoto, Shuzo, Shimizu, Hideo, Itoh, Yasunori, Tozawa, Keiichi, Kohri, Kenjiro

“…Objectives:  To clarify the role of renal tubular cell (RTC) injury and oxidative stress in the early stage of renal calcium oxalate crystal formation in a…”
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Mitochondrial permeability transition pore opening induces the initial process of renal calcium crystallization by Niimi, Kazuhiro, Yasui, Takahiro, Hirose, Masahito, Hamamoto, Shuzo, Itoh, Yasunori, Okada, Atsushi, Kubota, Yasue, Kojima, Yoshiyuki, Tozawa, Keiichi, Sasaki, Shoichi, Hayashi, Yutaro, Kohri, Kenjiro

“…Renal tubular cell injury induced by oxidative stress via mitochondrial collapse is thought to be the initial process of renal calcium crystallization…”
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Genome‐Wide Analysis of Genes Related to Kidney Stone Formation and Elimination in the Calcium Oxalate Nephrolithiasis Model Mouse: Detection of Stone‐Preventive Factors and Involvement of Macrophage Activity by Okada, Atsushi, Yasui, Takahiro, Hamamoto, Shuzo, Hirose, Masahito, Kubota, Yasue, Itoh, Yasunori, Tozawa, Keiichi, Hayashi, Yutaro, Kohri, Kenjiro

“…We previously established a mouse kidney stone formation model and showed that mice have a higher tolerance to stone formation than rats. Furthermore, we…”
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Efficacy of selective α1A adrenoceptor antagonist silodosin in the medical expulsive therapy for ureteral stones by Itoh, Yasunori, Okada, Atsushi, Yasui, Takahiro, Hamamoto, Shuzo, Hirose, Masahito, Kojima, Yoshiyuki, Tozawa, Keiichi, Sasaki, Shoichi, Kohri, Kenjiro

“…Recently, we reported that α1A adrenoceptor (AR) is the main participant in phenylephrine‐induced human ureteral contraction. We therefore decided to carry out…”
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Biomolecular mechanism of urinary stone formation involving osteopontin by Kohri, Kenjiro, Yasui, Takahiro, Okada, Atsushi, Hirose, Masahito, Hamamoto, Shuzo, Fujii, Yasuhiro, Niimi, Kazuhiro, Taguchi, Kazumi

“…Urinary stones consist of two phases-an inorganic (mineral) phase and an organic (matrix) phase. Studies on the organic components of kidney stones have been…”
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Clear cell sarcoma of the kidney distinguished from synovial sarcoma using genetic analysis: a case report by Hirose, Masahito, Mizuno, Kentaro, Kamisawa, Hideyuki, Nishio, Hidenori, Moritoki, Yoshinobu, Kohri, Kenjiro, Hayashi, Yutaro

“…The most common pediatric renal neoplasm is Wilms tumor, but clear cell sarcoma of the kidney or synovial sarcoma of the kidney are also sometimes encountered…”
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Successful formation of calcium oxalate crystal deposition in mouse kidney by intraabdominal glyoxylate injection by Okada, Atsushi, Nomura, Shintaro, Higashibata, Yuji, Hirose, Masahito, Gao, Bing, Yoshimura, Mugi, Itoh, Yasunori, Yasui, Takahiro, Tozawa, Keiichi, Kohri, Kenjiro

“…The establishment of an experimental animal model would be useful to study the mechanism of kidney stone formation. A calcium kidney stone model in rats…”
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Feasibility of metronomic chemotherapy with tegafur-uracil, cisplatin, and dexamethasone for docetaxel-refractory prostate cancer by Kubota, Hiroki, Fukuta, Katsuhiro, Yamada, Kenji, Hirose, Masahito, Naruyama, Hiromichi, Yanai, Yoshimasa, Yamada, Yasuyuki, Watase, Hideki, Kawai, Noriyasu, Tozawa, Keiichi, Yasui, Takahiro

“…Objectives: To evaluate the efficacy of tegafur–uracil (UFT), a prodrug of 5-fluorouracil, plus cisplatin and dexamethasone in patients with…”
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Crucial role of the cryptic epitope SLAYGLR within osteopontin in renal crystal formation of mice by Hamamoto, Shuzo, Yasui, Takahiro, Okada, Atsushi, Hirose, Masahito, Matsui, Yutaka, Kon, Shigeyuki, Sakai, Fumihiko, Kojima, Yoshiyuki, Hayashi, Yutaro, Tozawa, Keiichi, Uede, Toshimitsu, Kohri, Kenjiro

“…Osteopontin plays a crucial role in the formation of renal calcium crystals, which are primarily induced by renal tubular cell injury, especially mitochondrial…”
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Long-term follow-up of nephrotoxicity in rats administered both melamine and cyanuric acid by Yasui, Takahiro, Kobayashi, Takahiro, Okada, Atsushi, Hamamoto, Shuzo, Hirose, Masahito, Mizuno, Kentaro, Kubota, Yasue, Umemoto, Yukihiro, Kawai, Noriyasu, Tozawa, Keiichi, Gao, Bing, Kohri, Kenjiro

“…Melamine was recently identified as a risk factor for renal calculi following the milk powder contamination in China. However, the long-term natural history of…”
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Matrix Gla Protein is Involved in Crystal Formation in Kidney of Hyperoxaluric Rats by Lu, Xiuli, Gao, Bing, Yasui, Takahiro, Li, Yang, Liu, Ting, Mao, Xu, Hirose, Masahito, Wu, Yuhong, Yu, Daojun, Zhu, Qiwen, Kohri, Kenjiro, Xiao, Chunling

“…Background: Matrix Gla protein (MGP) is a molecular determinant regulating vascular calcification of the extracellular matrix. However, it is still unclear how…”
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The association between the incidence of urolithiasis and nutrition based on Japanese National Health and Nutrition Surveys by Yasui, Takahiro, Okada, Atsushi, Hamamoto, Shuzo, Hirose, Masahito, Ando, Ryosuke, Kubota, Yasue, Tozawa, Keiichi, Hayashi, Yutaro, Gao, Bing, Suzuki, Sadao, Kohri, Kenjiro

“…To clarify the association between regional variations in urolithiasis incidence and nutrition intake, we evaluated associated data from Japanese national…”
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NF-κB activation in renal tubular epithelial cells by oxalate stimulation by Tozawa, Keiichi, Yasui, Takahiro, Okada, Atsushi, Hirose, Masahito, Hamamoto, Shuzo, Itoh, Yasunori, Kohri, Kenjiro

“…Objectives:  The transcription factor nuclear factor–κB (NF–κB) is involved in inflammatory and immune responses through the induction of various cytokines and…”
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New therapy using bisphosphonate for urolithiasis by Yasui, Takahiro, Niimi, Kazuhiro, Hirose, Masahito

“…Osteoporosis is characterized by a reduction in bone mineral density (BMD) . Reduced BMD has been reported in urolithiasis patients with hypercalciuria, as…”
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Clinical Impact of Palliative Treatment Using Octreotide for Inoperable Malignant Bowel Obstruction Caused by Advanced Urological Cancer by Kubota, Hiroki, Taguchi, Kazumi, Kobayashi, Daichi, Naruyama, Hiromichi, Hirose, Masahito, Fukuta, Katsuhiro, Kubota, Yasue, Yasui, Takahiro, Yamada, Yasuyuki, Kohri, Kenjiro

“…Malignant bowel obstruction (MBO), an occasional complication in patients with advanced urological cancer, causes gastrointestinal symptoms such as nausea and…”
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Garcin syndrome as the initial presentation of metastatic adenocarcinoma of the prostate by Kubota, Hiroki, Naruyama, Hiromichi, Hirose, Masahito, Fukuta, Katsuhiro, Kubota, Yasue, Yamada, Yasuyuki, Kohri, Kenjiro

“…We describe an unusual case of metastasis of the skull base from prostate cancer. A 64-year-old man was referred for progressive cranial nerve palsies. Brain…”
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MP63-12 AN INVESTIGATIVE STUDY ON DRUG DISCOVERY UTILIZING THE CRYSTAL PHAGOCYTIC ABILITY OF MACROPHAGES THROUGH THE ANALYSIS OF AN FDA-APPROVED DRUG LIBRARY by Okada, Atsushi, Takase, Hiroshi, Unno, Rei, Taguchi, Kazumi, Niimi, Kazuhiro, Hamamoto, Shuzo, Ando, Ryosuke, Hirose, Masahito, Hashita, Tadahiro, Iwao, Takahiro, Matsunaga, Tamihide, Kohri, Kenjiro, Yasui, Takahiro

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Functional domains of osteopontin stimulate renal crystal formation: analysis of OPN-transgenic mice by Hamamoto, Shuzo, Yasui, Takahiro, Okada, Atushi, Hirose, Masahito, Kobayashi, Takahiro, Niimi, Kazuhiro, Fujii, Yasuhiro, Itoh, Yasunori, Tozawa, Keiichi, Kohri, Kenjiro

“…Osteopontin (OPN) has been described to play a nonredundant role in the formation of renal crystals. This biological activity of OPN may be attributed to its…”
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