Search Results - "Hironori Nakagami"

Development of COVID-19 vaccines utilizing gene therapy technology by Nakagami, Hironori

“…Abstract There is currently an outbreak of respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019…”
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Mechanisms underlying the bidirectional association between nonalcoholic fatty liver disease and hypertension by Nakagami, Hironori

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Challenges in the development of novel therapies, vaccines and siRNAs for the treatment of hypertension by Nakagami, Hironori

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New wave of digital hypertension management for clinical applications by Nakagami, Hironori

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Cellular senescence and senescence‐associated T cells as a potential therapeutic target by Nakagami, Hironori

“…More than 50 years ago, Hayflick et al. found that no long‐lived, proliferative cells remained in long‐term cell culture experiments; this phenomenon is called…”
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Recent Advances in Therapeutic Vaccines to Treat Hypertension by Nakagami, Hironori, Morishita, Ryuichi

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The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice by Yoshida, Shota, Nakagami, Hironori, Hayashi, Hiroki, Ikeda, Yuka, Sun, Jiao, Tenma, Akiko, Tomioka, Hideki, Kawano, Tomohiro, Shimamura, Munehisa, Morishita, Ryuichi, Rakugi, Hiromi

“…Senotherapy targeting for senescent cells is designed to attenuate age-related dysfunction. Senescent T cells, defined as CD4 + CD44 high CD62L low PD-1 +…”
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An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies by Liu, Yafei, Soh, Wai Tuck, Kishikawa, Jun-ichi, Hirose, Mika, Nakayama, Emi E., Li, Songling, Sasai, Miwa, Suzuki, Tatsuya, Tada, Asa, Arakawa, Akemi, Matsuoka, Sumiko, Akamatsu, Kanako, Matsuda, Makoto, Ono, Chikako, Torii, Shiho, Kishida, Kazuki, Jin, Hui, Nakai, Wataru, Arase, Noriko, Nakagawa, Atsushi, Matsumoto, Maki, Nakazaki, Yukoh, Shindo, Yasuhiro, Kohyama, Masako, Tomii, Keisuke, Ohmura, Koichiro, Ohshima, Shiro, Okamoto, Toru, Yamamoto, Masahiro, Nakagami, Hironori, Matsuura, Yoshiharu, Nakagawa, Atsushi, Kato, Takayuki, Okada, Masato, Standley, Daron M., Shioda, Tatsuo, Arase, Hisashi

“…Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein prevent SARS-CoV-2 infection. However, the effects of antibodies against…”
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Essential role for miR-196a in brown adipogenesis of white fat progenitor cells by Mori, Masaki, Nakagami, Hironori, Rodriguez-Araujo, Gerardo, Nimura, Keisuke, Kaneda, Yasufumi

“…The recent discovery of functional brown adipocytes in adult humans illuminates the potential of these cells in the treatment of obesity and its associated…”
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The mechanism of white and brown adipocyte differentiation by Nakagami, Hironori

“…Obesity gives vent to many diseases such as type 2 diabetes, hypertension, and hyperlipidemia, being considered as the main causes of mortality and morbidity…”
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Future Directions of Therapeutic Vaccines for Chronic Diseases by Nakamaru, Ryo, Nakagami, Hironori, Rakugi, Hiromi, Morishita, Ryuichi

“…Vaccines are well-known therapies for infectious disease and cancer; however, recently, we and others have developed vaccines for other chronic diseases, such…”
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Monitoring with wearable devices will clarify the association between indoor temperature and blood pressure by Nakagami, Hironori, Otsuka, Hiroki, Akiyama, Hitoshi

“…The association of blood pressure and temperature is well known in seasonal observation, and low temperature in the winter season is often considered a cause…”
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A novel soluble epoxide hydrolase vaccine protects murine cardiac muscle against myocardial infarction by Kitsuka, Takahiro, Shiraki, Aya, Oyama, Jun-ichi, Nakagami, Hironori, Tanaka, Atsushi, Node, Koichi

“…Myocardial infarction is still a life-threatening disease, even though its prognosis has been improved through the development of percutaneous coronary…”
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Brief report on a phase I/IIa study to assess the safety, tolerability, and immune response of AGMG0201 in patients with essential hypertension by Nakagami, Hironori, Ishihama, Tetsuya, Daikyoji, Yuichi, Sasakura, Chieka, Yamada, Ei, Morishita, Ryuichi

“…We have been developing an angiotensin II vaccine for hypertension. We conducted a placebo-controlled dose escalation study to investigate the safety,…”
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SARS-CoV-2-induced humoral immunity through B cell epitope analysis in COVID-19 infected individuals by Yoshida, Shota, Ono, Chikako, Hayashi, Hiroki, Fukumoto, Shinya, Shiraishi, Satoshi, Tomono, Kazunori, Arase, Hisashi, Matsuura, Yoshiharu, Nakagami, Hironori

“…The aim of this study is to understand adaptive immunity to SARS-CoV-2 through the analysis of B cell epitope and neutralizing activity in coronavirus disease…”
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Pathophysiology of cardiovascular disease in diabetes mellitus by Rodriguez-Araujo, Gerardo, Nakagami, Hironori

“…Diabetes mellitus elicits cellular, epigenetic, and post-translational changes that directly or indirectly affect the biology of the vasculature and other…”
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Author Correction: A novel soluble epoxide hydrolase vaccine protects murine cardiac muscle against myocardial infarction by Kitsuka, Takahiro, Shiraki, Aya, Oyama, Jun‑ichi, Nakagami, Hironori, Tanaka, Atsushi, Node, Koichi

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Blood pressure fluctuations and the indoor environment in a highly insulated and airtight model house during the cold winter season by Nakagami, Hironori, Akiyama, Hiroshi, Otsuka, Hiroki, Iwamae, Atsushi, Yamada, Hidekazu

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Evaluation of the Genetic Risk of Hypertension-Related Diseases by Nakagami, Hironori

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Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes by Yokota, Harumasa, Hayashi, Hiroki, Hanaguri, Junya, Yamagami, Satoru, Kushiyama, Akifumi, Nakagami, Hironori, Nagaoka, Taiji

“…Prorenin is viewed as an ideal target molecule in the prevention of diabetic retinopathy. However, no drugs are available for inhibiting activation of…”
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