Search Results - "Hiron, Martine"

Gene profiling in white blood cells predicts infliximab responsiveness in rheumatoid arthritis by Lequerré, Thierry, Gauthier-Jauneau, Anne-Christine, Bansard, Carine, Derambure, Céline, Hiron, Martine, Vittecoq, Olivier, Daveau, Maryvonne, Mejjad, Othmane, Daragon, Alain, Tron, François, Le Loët, Xavier, Salier, Jean-Philippe

“…As indicators of responsiveness to a tumour necrosis factor (TNF)alpha blocking agent (infliximab) are lacking in rheumatoid arthritis, we have used gene…”
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Transient and etiology-related transcription regulation in cirrhosis prior to hepatocellular carcinoma occurrence by Caillot, Frederique, Derambure, Celine, Bioulac-Sage, Paulette, Francois, Arnaud, Scotte, Michel, Goria, Odile, Hiron, Martine, Daveau, Maryvonne, Salier, Jean Philippe

“…AIM： To search for transcription dysregulation that could （1） differentiate hepatocellular carcinoma （HCC）-free from HCC-related cirrhosis （2） differentiate…”
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Effects of glutamine supplementation on gut barrier, glutathione content and acute phase response in malnourished rats during inflammatory shock by Belmonte, Liliana, Coëffier, Moïse, Le Pessot, Florence, Miralles-Barrachina, Olga, Hiron, Martine, Leplingard, Antony, Lemeland, Jean-François, Hecketsweiler, Bernadette, Daveau, Maryvonne, Ducrotté, Philippe, Déchelotte, Pierre

“…To evaluate the effect of glutamine on intestinal mucosa integrity, glutathione stores and acute phase response in protein-depleted rats during an inflammatory…”
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Genome-wide differences in hepatitis C- vs alcoholism-associated hepatocellular carcinoma by Derambure, Celine, Coulouarn, Cedric, Caillot, Frederique, Daveau, Romain, Hiron, Martine, Scotte, Michel, Francois, Arnaud, Duclos, Celia, Goria, Odile, Gueudin, Marie, Cavard, Catherine, Terris, Benoit, Daveau, Maryvonne, Salier, Jean-Philippe

“…AIM： To look at a comprehensive picture of etiologydependent gene abnormalities in hepatocellular carcinoma in Western Europe. METHODS： With a liver-oriented…”
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Global gene repression in hepatocellular carcinoma and fetal liver, and suppression of dudulin-2 mRNA as a possible marker for the cirrhosis-to-tumor transition by Coulouarn, Cédric, Derambure, Céline, Lefebvre, Grégory, Daveau, Romain, Hiron, Martine, Scotte, Michel, François, Arnaud, Daveau, Maryvonne, Salier, Jean-Philippe

“…Whether the transcriptional reprogramming process induced by hepatocellular carcinoma recapitulates that of the developing liver is at present unclear. With a…”
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Genome-wide response of the human Hep3B hepatoma cell to proinflammatory cytokines, from transcription to translation by COULOUARN, Cédric, LEFEBVRE, Grégory, DAVEAU, Romain, LETELLIER, Franck, HIRON, Martine, DROUOT, Laurent, DAVEAU, Maryvonne, SALIER, Jean-Philippe

“…Given the unknown timing of the onset of an acute systemic inflammation in humans, the fine tuning of cascades and pathways involved in the associated…”
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Dysregulation of RasGRP1 in rheumatoid arthritis and modulation of RasGRP3 as a biomarker of TNFα inhibitors by Golinski, Marie-Laure, Vandhuick, Thibault, Derambure, Céline, Fréret, Manuel, Lecuyer, Matthieu, Guillou, Clément, Hiron, Martine, Boyer, Olivier, Le Loët, Xavier, Vittecoq, Olivier, Lequerré, Thierry

“…B and T cells play a key role in rheumatoid arthritis (RA) pathophysiology. RasGRP1 and RasGRP3 are involved in T and B cell receptors signaling, and belong to…”
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Dysregulation of RasGRP1 in rheumatoid arthritis and modulation of RasGRP3 as a biomarker of TNF[alpha] inhibitors by Golinski, Marie-Laure, Vandhuick, Thibault, Derambure, Cñline, Frñret, Manuel, Lecuyer, Matthieu, Guillou, Clñment, Hiron, Ma, Boyer, Olivier, Le Loët, Xavier, Vittecoq, Olivier, Lequerrñ, Thierry

“…Background B and T cells play a key role in rheumatoid arthritis (RA) pathophysiology. RasGRP1 and RasGRP3 are involved in T and B cell receptors signaling,…”
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Dysregulation of RasGRP1 in rheumatoid arthritis and modulation of RasGRP3 as a biomarker of TNFAlpha inhibitors by Golinski, Marie-Laure, Thibault Vandhuick, Derambure, Celine, Freret, Manuel, Lecuyer, Matthieu, Guillou, Clement, Hiron, Martine, Boyer, Olivier, Xavier Le Loet, Vittecoq, Olivier, Lequerre, Thierry

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Characterization of the transcriptional signature of C/EBPbeta isoforms (LAP/LIP) in Hep3B cells: Implication of LIP in pro-survival functions by Saint-Auret, Gaëlle, Danan, Jean-Louis, Hiron, Martine, Blache, Céline, Sulpice, Eric, Tendil, Simon, Daveau, Maryvonne, Gidrol, Xavier, Salier, Jean-Philippe

“…Background & Aims C/EBPbeta is an important mediator of several cellular processes, such as differentiation, proliferation, and survival of hepatic cells…”
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Gene profiling predicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra) by BANSARD, Carine, LEQUERRE, Thierry, LE LOËT, Xavier, SALIER, Jean-Philippe, DERAMBURE, Céline, VITTECOQ, Olivier, HIRON, Martine, DARAGON, Alain, POUPLIN, Sophie, DAVEAU, Maryvonne, BOYER, Olivier, TRON, François

“…The overall non-response rate to biologics remains 30-40% for patients with RA resistant to MTX. The objective of this study was to predict responsiveness to…”
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Hepatocyte growth factor, transforming growth factor α, and their receptors as combined markers of prognosis in hepatocellular carcinoma by Daveau, Maryvonne, Scotte, Michel, François, Arnaud, Coulouarn, Cédric, Ros, Gilles, Tallet, Yveline, Hiron, Martine, Hellot, Marie-France, Salier, Jean-Philippe

“…A change in the balance between proliferation and apoptosis in the course of hepatocellular carcinoma (HCC) development and progression has been suspected. We…”
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Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia by Lequerré, Thierry, Bansard, Carine, Vittecoq, Olivier, Derambure, Céline, Hiron, Martine, Daveau, Maryvonne, Tron, François, Ayral, Xavier, Biga, Norman, Auquit-Auckbur, Isabelle, Chiocchia, Gilles, Le Loët, Xavier, Salier, Jean-Philippe

“…Rheumatoid arthritis (RA) is a heterogeneous disease and its underlying molecular mechanisms are still poorly understood. Because previous microarray studies…”
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Heme and acute inflammation by Lyoumi, Saïd, Puy, Hervé, Tamion, Fabienne, Bogard, Catherine, Leplingard, Antony, Scotté, Michel, Vranckx, Roger, Gauthier, Francis, Hiron, Martine, Daveau, Maryvonne, Nordmann, Yves, Deybach, Jean Charles, Lebreton, Jean Pierre

“…Acute‐phase protein synthesis in the liver during inflammation is regulated via cytokines and glucocorticoids. Using quantitative reverse transcription…”
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Down-regulated expression of the TSAP6 protein in liver is associated with a transition from cirrhosis to hepatocellular carcinoma by Caillot, Frédérique, Daveau, Romain, Daveau, Maryvonne, Lubrano, Jean, Saint-Auret, Gaëlle, Hiron, Martine, Goria, Odile, Scotte, Michel, Francois, Arnaud, Salier, Jean-Philippe

“…Aims:  Hepatocellular carcinoma (HCC) results from cirrhosis and, in Western Europe, hepatitis C virus and alcoholism are the predominant causes of this…”
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Expression of a Functional C5a Receptor in Regenerating Hepatocytes and Its Involvement in a Proliferative Signaling Pathway in Rat by Daveau, Maryvonne, Benard, Magalie, Scotte, Michel, Schouft, Marie-Therese, Hiron, Martine, Francois, Arnaud, Salier, Jean-Philippe, Fontaine, Marc

“…Activation of the complement system generates the anaphylatoxin C5a whose activities are mediated through its binding to the widely expressed C5aR. C5aR mRNA…”
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The inflammation‐induced down‐regulation of plasma Fetuin‐A (α2HS‐Glycoprotein) in liver results from the loss of interaction between long C/EBP isoforms at two neighbouring binding sites by Gangneux, Christophe, Daveau, Maryvonne, Hiron, Martine, Derambure, Céline, Papaconstantinou, John, Salier, Jean‐Philippe

“…Fetuin‐A is an hepatic protein whose mRNA transiently falls during the inflammatory acute phase via unknown transcriptional mechanisms. Various FETUA…”
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Novel Serum Markers of Fibrosis Progression for the Follow-Up of Hepatitis C Virus-Infected Patients by Caillot, Frédérique, Hiron, Martine, Goria, Odile, Gueudin, Marie, Francois, Arnaud, Scotte, Michel, Daveau, Maryvonne, Salier, Jean-Philippe

“…Liver biopsy is considered the gold-standard method for the assessment of liver fibrosis during follow-up of hepatitis C virus-infected patients, but this…”
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Reduced synthesis of inflammatory cytokines by a free radical scavenger after hemorrhagic shock in rats by Tamion, Fabienne, Richard, Vincent, Bonmarchand, Guy, Leroy, Jacky, Hiron, Martine, Daveau, Maryvonne, Thuillez, Christian, Lebreton, Jean-Pierre

“…OBJECTIVESIntestinal ischemia/reperfusion during hemorrhage and resuscitation may be a major trigger for cytokine expression. To assess whether free radicals…”
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Gene profiling in white blood cells predicts infliximab responsiveness in rheumatoid arthritis by Lequerré, Thierry, Gauthier-Jauneau, Anne-Christine, Bansard, Carine, Derambure, Céline, Hiron, Martine, Vittecoq, Olivier, Daveau, Maryvonne, Mejjad, Othmane, Daragon, Alain, Tron, François, Le Loët, Xavier, Salier, Jean-Philippe

“…As indicators of responsiveness to a tumour necrosis factor (TNF)alpha blocking agent (infliximab) are lacking in rheumatoid arthritis, we have used gene…”
Get full text