Search Results - "Hiromasa Araki"
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Clinical practice pattern in patients with advanced urothelial cancer who had progressed on pembrolizumab in the pre‐enfortumab vedotin era
Published in International journal of urology (01-07-2022)“…Objectives Pembrolizumab, an anti‐PD‐1 monoclonal antibody, revolutionized the treatment for advanced urothelial carcinoma. However, the standard treatment for…”
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Pembrolizumab for treating advanced urothelial carcinoma in patients with impaired performance status: Analysis of a Japanese nationwide cohort
Published in Cancer medicine (Malden, MA) (01-05-2021)“…Background The benefits of pembrolizumab in patients with advanced urothelial carcinoma (UC) and impaired performance status (PS) remain unknown. This study…”
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Predictive factors and radiological findings of adrenohepatic adhesion during laparoscopic adrenalectomy
Published in Investigative and clinical urology (01-05-2020)“…This retrospective study aimed to identify predictive factors and imaging features of adrenohepatic adhesion found during laparoscopic right adrenalectomy…”
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The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection
Published in The Journal of clinical investigation (01-06-2001)“…Protease-activated receptor-2 (PAR-2), a receptor activated by trypsin/tryptase, modulates smooth muscle tone and exocrine secretion in the salivary glands and…”
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Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells
Published in Respiratory research (16-04-2007)“…Proteinase-activated receptors (PARs; PAR1-4) that can be activated by serine proteinases such as thrombin and neutrophil catepsin G are known to contribute to…”
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Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus
Published in Virology (New York, N.Y.) (01-03-2004)“…Small interfering RNA (siRNA) is currently being evaluated not only as a powerful tool for functional genomics, but also as a potentially promising therapeutic…”
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Protease-activated receptor 4-mediated Ca2+ signaling in mouse lung alveolar epithelial cells
Published in Life sciences (1973) (16-08-2007)“…Protease-activated receptor (PAR)-4 is a recently identified low-affinity thrombin receptor that plays a pathophysiological role in many types of tissues…”
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Stereodivergent synthesis of both (2 S)- and (2 R)-1-monoricinolein derivatives by lipase-catalyzed hydrolysis or transesterification directed to new ferroelectric liquid crystals
Published in Tetrahedron: asymmetry (16-05-2007)“…The preparation of both (2 S)- and (2 R)-1-monoricinolein derivatives has been developed to synthesize ferroelectric liquid crystals. Lipase-catalyzed…”
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Suppression by protease-activated receptor-2 activation of gastric acid secretion in rats
Published in European journal of pharmacology (28-06-2002)“…Activation of protease-activated receptor-2 (PAR-2), a receptor activated by trypsin/tryptase, induces neurally mediated gastric mucus secretion accompanied by…”
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Exploiting cis-Acting Replication Elements To Direct Hepatitis C Virus-Dependent Transgene Expression
Published in Journal of Virology (01-05-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in rats: involvement of PAR-2 and non-PAR-2 mechanisms
Published in The Journal of pharmacology and experimental therapeutics (01-01-2005)“…Protease-activated receptor-2 (PAR-2) plays an extensive role in the regulation of digestive exocrine secretion. The present study examined whether…”
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Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle
Published in Life sciences (1973) (06-10-2000)“…Activation of protease-activated receptor-1 (PAR-1) produces a dual action, apamin-sensitive relaxation followed by contraction, in the rat duodenal smooth…”
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O3E3-1 Protease-activated receptor 4-mediated phenotypic changes in alveolar epithelial cells
Published in Journal of Pharmacological Sciences (2007)Get full text
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Impact of histological variants on outcomes in patients with urothelial carcinoma treated with pembrolizumab: a propensity score matching analysis
Published in BJU international (01-08-2022)“…Objectives To assess the impact of histological variants on survival and response to treatment with pembrolizumab in patients with chemo‐resistant urothelial…”
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P2N-17 PAR2 signaling for production of IL-8 and prostaglandin E2 in human lung epithelial cells
Published in Journal of Pharmacological Sciences (2006)Get full text
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P2M-28 Protease activated receptor-1 -mediated activation of focal adhesion kinase in rat cardiomyocytes
Published in Journal of Pharmacological Sciences (2006)Get full text
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